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Top Articles

#TitleJournalYearCitations
1The nuclear RNase III Drosha initiates microRNA processingNature20034,463
2RNA velocity of single cellsNature20182,602
3Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.Free Radical Biology and Medicine20012,223
4Pericytes regulate the blood–brain barrierNature20102,214
5Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and PromisesDevelopmental Cell20112,123
6Physiological functions of thioredoxin and thioredoxin reductaseFEBS Journal20002,091
7The Human Transcription FactorsCell20182,048
8Molecular Architecture of the Mouse Nervous SystemCell20182,002
9Visualization and analysis of gene expression in tissue sections by spatial transcriptomicsScience20161,983
10Role of platelet-derived growth factors in physiology and medicineGenes and Development20081,904
11Endothelial/Pericyte InteractionsCirculation Research20051,748
12Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencingNature Neuroscience20151,710
13Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic SyndromeMolecular Cell19981,654
14Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease riskNature Genetics20191,625
15The Human Cell AtlasELife20171,547
16Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesisNature20071,515
17Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift AssayScience20131,444
18Short-chain dehydrogenases/reductases (SDR)Biochemistry19951,230
19From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human HealthAntioxidants and Redox Signaling20071,089
20Quantitative single-cell RNA-seq with unique molecular identifiersNature Methods20141,047
21Apolipoprotein E controls cerebrovascular integrity via cyclophilin ANature20121,019
22Single-cell sequencing-based technologies will revolutionize whole-organism scienceNature Reviews Genetics20131,012
23Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell DeathCell Metabolism20081,009
24Hallmarks of cancer: Interactions with the tumor stromaExperimental Cell Research2010955
25Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced FerroptosisCell2018920
26Impact of cytosine methylation on DNA binding specificities of human transcription factorsScience2017912
27The cellular thermal shift assay for evaluating drug target interactions in cellsNature Protocols2014900
28Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligenceNature Genetics2018893
29CRISPR–Cas9 genome editing induces a p53-mediated DNA damage responseNature Medicine2018874
30Origin, fate and dynamics of macrophages at central nervous system interfacesNature Immunology2016872
31Counting absolute numbers of molecules using unique molecular identifiersNature Methods2012869
32Arrest of -Amyloid Fibril Formation by a Pentapeptide LigandJournal of Biological Chemistry1996850
33Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation EmbryosCell2016830
34Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seqGenome Research2011828
35(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonateNature Chemical Biology2009822
36[21] Thioredoxin and thioredoxin reductaseMethods in Enzymology1995812
37Tracking cancer drugs in living cells by thermal profiling of the proteomeScience2014812
38Functional receptor for GDNF encoded by the c-ret proto-oncogeneNature1996785
39Endothelial-Mural Cell Signaling in Vascular Development and AngiogenesisArteriosclerosis, Thrombosis, and Vascular Biology2009784
40Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell SequencingCell2018777
41Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumorsNature Medicine2004746
42Medium- and short-chain dehydrogenase/reductase gene and protein familiesCellular and Molecular Life Sciences2008738
43Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokinesNature Medicine2014734
44Toward a unified nomenclature for mammalian ADP-ribosyltransferasesTrends in Biochemical Sciences2010724
45Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral EffectsJournal of Neuroscience2003720
46Mechanisms underlying mutational signatures in human cancersNature Reviews Genetics2014703
47The Expression of the Gene Coding for the Antibacterial Peptide LL-37 Is Induced in Human Keratinocytes during Inflammatory DisordersJournal of Biological Chemistry1997698
48Replication stress links structural and numerical cancer chromosomal instabilityNature2013694
49Molecular Diversity of Midbrain Development in Mouse, Human, and Stem CellsCell2016687
50Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20–30 yearsChemosphere2000674