# | Title | Journal | Year | Citations |
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1 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
2 | Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease | Nature Medicine | 1996 | 2,545 |
3 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
4 | Poverty and obesity: the role of energy density and energy costs | American Journal of Clinical Nutrition | 2004 | 1,978 |
5 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
6 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
7 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
8 | Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature | Journal of Neuropathology and Experimental Neurology | 2012 | 1,599 |
9 | A Controlled Trial of a Human Papillomavirus Type 16 Vaccine | New England Journal of Medicine | 2002 | 1,548 |
10 | Systematic identification of trans eQTLs as putative drivers of known disease associations | Nature Genetics | 2013 | 1,544 |
11 | Long-Term Exposure to Air Pollution and Incidence of Cardiovascular Events in Women | New England Journal of Medicine | 2007 | 1,538 |
12 | Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study | Lancet, The | 2011 | 1,495 |
13 | Human papillomavirus type distribution in invasive cervical cancer and high-grade cervical lesions: A meta-analysis update | International Journal of Cancer | 2007 | 1,452 |
14 | Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial | Lancet Oncology, The | 2005 | 1,400 |
15 | Pathways to Diabetic Limb Amputation: Basis for Prevention | Diabetes Care | 1990 | 1,365 |
16 | Nosocomial Acquisition ofClostridium difficileInfection | New England Journal of Medicine | 1989 | 1,320 |
17 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
18 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
19 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
20 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
21 | Primary age-related tauopathy (PART): a common pathology associated with human aging | Acta Neuropathologica | 2014 | 1,060 |
22 | Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the Global Burden of Disease Study 2010 | The Lancet Global Health | 2013 | 1,051 |
23 | Urinary and Sexual Function After Radical Prostatectomy for Clinically Localized Prostate Cancer | JAMA - Journal of the American Medical Association | 2000 | 1,036 |
24 | A Cohort Study of the Risk of Cervical Intraepithelial Neoplasia Grade 2 or 3 in Relation to Papillomavirus Infection | New England Journal of Medicine | 1992 | 927 |
25 | Hypertriglyceridemia as a Cardiovascular Risk Factor | American Journal of Cardiology | 1998 | 906 |
26 | Epidemiology of Genital Human Papillomavirus Infection | American Journal of Medicine | 1997 | 889 |
27 | Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms | Gastroenterology | 2003 | 841 |
28 | Genital Human Papillomavirus Infection: Incidence and Risk Factors in a Cohort of Female University Students | American Journal of Epidemiology | 2003 | 830 |
29 | Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits | PLoS Genetics | 2011 | 796 |
30 | A New Respiratory Tract Pathogen: Chlamydia pneumoniae Strain TWAR | Journal of Infectious Diseases | 1990 | 794 |
31 | DNA methylation-based measures of biological age: meta-analysis predicting time to death | Aging | 2016 | 786 |
32 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
33 | The use of brief interventions adapted from motivational interviewing across behavioral domains: a systematic review | Addiction | 2001 | 742 |
34 | New loci associated with kidney function and chronic kidney disease | Nature Genetics | 2010 | 710 |
35 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
36 | Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study | American Journal of Epidemiology | 2006 | 686 |
37 | Ovarian Tumors in a Cohort of Infertile Women | New England Journal of Medicine | 1994 | 684 |
38 | Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014 | JAMA - Journal of the American Medical Association | 2016 | 669 |
39 | Dementia and Alzheimer Disease Incidence | Archives of Neurology | 2002 | 668 |
40 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
41 | Plasma triglyceride and coronary heart disease. | Arteriosclerosis and Thrombosis: A Journal of Vascular Biology | 1991 | 651 |
42 | Midlife and Late-Life Obesity and the Risk of Dementia | Archives of Neurology | 2009 | 618 |
43 | Condom Use and the Risk of Genital Human Papillomavirus Infection in Young Women | New England Journal of Medicine | 2006 | 609 |
44 | Pregnancy complications and outcomes among overweight and obese nulliparous women | American Journal of Public Health | 2001 | 606 |
45 | Plasma Triglyceride Level is a Risk Factor for Cardiovascular Disease Independent of High-Density Lipoprotein Cholesterol Level: A Metaanalysis of Population-Based Prospective Studies | European Journal of Cardiovascular Prevention and Rehabilitation | 1996 | 604 |
46 | Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE‐AF Consortium | Journal of the American Heart Association | 2013 | 601 |
47 | Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge | Nature Genetics | 2010 | 591 |
48 | Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction | Nature | 2015 | 581 |
49 | Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: a combined analysis of three randomised clinical trials | Lancet, The | 2007 | 579 |
50 | Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients | Breast Cancer Research | 2007 | 576 |