# | Title | Journal | Year | Citations |
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1 | Structure and Regulation of Voltage-Gated Ca2+Channels | Annual Review of Cell and Developmental Biology | 2000 | 2,115 |
2 | From Ionic Currents to Molecular Mechanisms | Neuron | 2000 | 1,920 |
3 | Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms | Physiological Reviews | 1995 | 1,712 |
4 | International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels | Pharmacological Reviews | 2005 | 1,481 |
5 | Mechanism of auxin perception by the TIR1 ubiquitin ligase | Nature | 2007 | 1,367 |
6 | Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors | Science | 2005 | 1,357 |
7 | The crystal structure of a voltage-gated sodium channel | Nature | 2011 | 1,278 |
8 | Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor | Nature | 2010 | 1,192 |
9 | Structure and function of voltage-sensitive ion channels | Science | 1988 | 1,175 |
10 | Voltage-Gated Calcium Channels | Cold Spring Harbor Perspectives in Biology | 2011 | 1,156 |
11 | International Union of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels | Pharmacological Reviews | 2005 | 1,110 |
12 | The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands | Nucleic Acids Research | 2016 | 1,075 |
13 | Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling | Annual Review of Biochemistry | 2007 | 1,060 |
14 | Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy | Nature Neuroscience | 2006 | 985 |
15 | Modulation of neurodegeneration by molecular chaperones | Nature Reviews Neuroscience | 2005 | 957 |
16 | Ubiquitin Ligases: Structure, Function, and Regulation | Annual Review of Biochemistry | 2017 | 917 |
17 | Structure and Function of Voltage-Gated Ion Channels | Annual Review of Biochemistry | 1995 | 871 |
18 | Nomenclature of Voltage-Gated Calcium Channels | Neuron | 2000 | 868 |
19 | NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants | Nature | 2012 | 834 |
20 | Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors | Trends in Pharmacological Sciences | 1990 | 830 |
21 | Cross Talk between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation | Neuron | 1998 | 820 |
22 | Modulation of Ca2+ channels βγ G-protein py subunits | Nature | 1996 | 808 |
23 | Molecular determinants of state-dependent block of Na+ channels by local anesthetics | Science | 1994 | 797 |
24 | Cyclic nucleotide research — still expanding after half a century | Nature Reviews Molecular Cell Biology | 2002 | 792 |
25 | Cellular and molecular biology of voltage-gated sodium channels | Physiological Reviews | 1992 | 758 |
26 | A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 754 |
27 | Rhodopsin dimers in native disc membranes | Nature | 2003 | 732 |
28 | Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits. | Journal of Cell Biology | 1993 | 706 |
29 | Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions | Current Opinion in Cell Biology | 2000 | 690 |
30 | A p53-dependent mouse spindle checkpoint | Science | 1995 | 683 |
31 | D14–SCFD3-dependent degradation of D53 regulates strigolactone signalling | Nature | 2013 | 669 |
32 | Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways | Oncogene | 1999 | 660 |
33 | Molecular mechanisms of neurotoxin action on voltage-gated sodium channels | Biochimie | 2000 | 656 |
34 | Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development | Cell | 2014 | 637 |
35 | The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus | Neuron | 2006 | 632 |
36 | Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel | Science | 1992 | 632 |
37 | Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration | Journal of Neuroscience | 2003 | 605 |
38 | Biochemical properties and subcellular distribution of an N-type calcium hannel α1 subunit | Neuron | 1992 | 592 |
39 | Making New Connections | Neuron | 1999 | 579 |
40 | Voltage‐gated sodium channels at 60: structure, function and pathophysiology | Journal of Physiology | 2012 | 562 |
41 | Voltage-gated ion channels and gating modifier toxins | Toxicon | 2007 | 560 |
42 | Induction of CRE-Mediated Gene Expression by Stimuli That Generate Long-Lasting LTP in Area CA1 of the Hippocampus | Neuron | 1996 | 555 |
43 | Calcium Channel Regulation and Presynaptic Plasticity | Neuron | 2008 | 554 |
44 | Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channels | Journal of Neuroscience | 1995 | 547 |
45 | Autistic-like behaviour in Scn1a+/− mice and rescue by enhanced GABA-mediated neurotransmission | Nature | 2012 | 543 |
46 | Auxiliary subunits of voltage-gated ion channels | Neuron | 1994 | 541 |
47 | The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons | Journal of Neuroscience | 1999 | 536 |
48 | Overview of the voltage-gated sodium channel family | Genome Biology | 2003 | 525 |
49 | The Dysphoric Component of Stress Is Encoded by Activation of the Dynorphin κ-Opioid System | Journal of Neuroscience | 2008 | 525 |
50 | Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. | Molecular and Cellular Biology | 1994 | 521 |