| # | Title | Journal | Year | Citations |
|---|
| 1 | Integrative Clinical Genomics of Advanced Prostate Cancer | Cell | 2015 | 2,660 |
| 2 | Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma | JAMA - Journal of the American Medical Association | 2015 | 1,874 |
| 3 | Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells | Infection and Immunity | 2005 | 1,711 |
| 4 | MicroRNA profiling: approaches and considerations | Nature Reviews Genetics | 2012 | 1,453 |
| 5 | Impact of 16S rRNA Gene Sequence Analysis for Identification of Bacteria on Clinical Microbiology and Infectious Diseases | Clinical Microbiology Reviews | 2004 | 1,452 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 7 | Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8 + and CD4 + CD19-specific chimeric antigen receptor–modified T cells | Science Translational Medicine | 2016 | 832 |
| 8 | Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies | Cancer Prevention Research | 2012 | 784 |
| 9 | Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy | Blood | 2017 | 774 |
| 10 | Classification and characterization of microsatellite instability across 18 cancer types | Nature Medicine | 2016 | 726 |
| 11 | Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series | Lancet, The | 2020 | 678 |
| 12 | Selective Silencing of Foreign DNA with Low GC Content by the H-NS Protein in Salmonella | Science | 2006 | 672 |
| 13 | Plasma Viremia in Human Immunodeficiency Virus Infection | New England Journal of Medicine | 1989 | 635 |
| 14 | Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells | Blood | 2008 | 628 |
| 15 | Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy | Blood | 2016 | 622 |
| 16 | The long tail of oncogenic drivers in prostate cancer | Nature Genetics | 2018 | 601 |
| 17 | Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 591 |
| 18 | Bacterial Communities in Women with Bacterial Vaginosis: High Resolution Phylogenetic Analyses Reveal Relationships of Microbiota to Clinical Criteria | PLoS ONE | 2012 | 545 |
| 19 | An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease | Genome Biology | 2016 | 535 |
| 20 | Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration | Cell Metabolism | 2006 | 519 |
| 21 | Comparison of Western blot (immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human sera | Journal of Clinical Microbiology | 1988 | 519 |
| 22 | Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer | JAMA Oncology | 2017 | 510 |
| 23 | Emergence of ganciclovir-resistant cytomegalovirus disease among recipients of solid-organ transplants | Lancet, The | 2000 | 505 |
| 24 | Performance Characteristics of the Abbott Architect SARS-CoV-2 IgG Assay and Seroprevalence in Boise, Idaho | Journal of Clinical Microbiology | 2020 | 496 |
| 25 | Using synthetic templates to design an unbiased multiplex PCR assay | Nature Communications | 2013 | 489 |
| 26 | Global and Regional Estimates of Prevalent and Incident Herpes Simplex Virus Type 1 Infections in 2012 | PLoS ONE | 2015 | 464 |
| 27 | The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry | Journal of Immunological Methods | 2009 | 456 |
| 28 | Outcome of sustained virological responders with histologically advanced chronic hepatitis C | Hepatology | 2010 | 428 |
| 29 | 临床实践中治疗性单采术应用指南——基于美国血浆置换学会编写委员会的循证策略：第七版 | Journal of Clinical Apheresis | 2016 | 421 |
| 30 | Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical associations | Blood | 1996 | 413 |
| 31 | Probiotic Bacteria Reduce Salmonella Typhimurium Intestinal Colonization by Competing for Iron | Cell Host and Microbe | 2013 | 413 |
| 32 | A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM | Diabetologia | 1994 | 404 |
| 33 | History of Circumcision, Medical Conditions, and Sexual Activity and Risk of Penile Cancer | Journal of the National Cancer Institute | 1993 | 403 |
| 34 | The Human Cytomegalovirus Chemokine Receptor US28 Mediates Vascular Smooth Muscle Cell Migration | Cell | 1999 | 402 |
| 35 | Comparative Performance of SARS-CoV-2 Detection Assays Using Seven Different Primer-Probe Sets and One Assay Kit | Journal of Clinical Microbiology | 2020 | 401 |
| 36 | Guidelines on the Use of Therapeutic Apheresis in Clinical Practice–Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue | Journal of Clinical Apheresis | 2016 | 384 |
| 37 | International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease | Blood | 2017 | 381 |
| 38 | PGC-1α Rescues Huntington’s Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function | Science Translational Medicine | 2012 | 376 |
| 39 | Identification of a Human Heme Exporter that Is Essential for Erythropoiesis | Cell | 2004 | 375 |
| 40 | Infectious complications of CD19-targeted chimeric antigen receptor–modified T-cell immunotherapy | Blood | 2018 | 374 |
| 41 | Genetic Mechanisms of Immune Evasion in Colorectal Cancer | Cancer Discovery | 2018 | 367 |
| 42 | Global Estimates of Prevalent and Incident Herpes Simplex Virus Type 2 Infections in 2012 | PLoS ONE | 2015 | 366 |
| 43 | Diurnal variation of tissue-type plasminogen activator and its rapid inhibitor (PAI-1). | Circulation | 1989 | 364 |
| 44 | Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein | Lancet, The | 1991 | 347 |
| 45 | Actionable, Pathogenic Incidental Findings in 1,000 Participants’ Exomes | American Journal of Human Genetics | 2013 | 342 |
| 46 | Persistence of HIV-1 receptor–positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition | Nature Medicine | 2009 | 341 |
| 47 | Microsatellite Instability Detection by Next Generation Sequencing | Clinical Chemistry | 2014 | 333 |
| 48 | Colon and Endometrial Cancers With Mismatch Repair Deficiency Can Arise From Somatic, Rather Than Germline, Mutations | Gastroenterology | 2014 | 328 |
| 49 | Clinical Laboratory Practice Recommendations for the Use of Cardiac Troponin in Acute Coronary Syndrome: Expert Opinion from the Academy of the American Association for Clinical Chemistry and the Task Force on Clinical Applications of Cardiac Bio-Markers of the International Federation of Clinical Chemistry and Laboratory Medicine | Clinical Chemistry | 2018 | 327 |
| 50 | Transfusion reactions: prevention, diagnosis, and treatment | Lancet, The | 2016 | 326 |
