| # | Title | Journal | Year | Citations |
|---|
| 1 | The impact of translocations and gene fusions on cancer causation | Nature Reviews Cancer | 2007 | 1,191 |
| 2 | Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics | Modern Pathology | 2014 | 585 |
| 3 | The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias | Nature Genetics | 2015 | 405 |
| 4 | Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia | Leukemia | 2015 | 280 |
| 5 | Clustering of aberrations to specific chromosomes in human neoplasms | Hereditas | 2009 | 253 |
| 6 | Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor | Genes Chromosomes and Cancer | 2013 | 238 |
| 7 | A novel SERPINE1–FOSB fusion gene results in transcriptional up‐regulation of FOSB in pseudomyogenic haemangioendothelioma | Journal of Pathology | 2014 | 174 |
| 8 | A field guide for cancer diagnostics using cell‐free DNA: From principles to practice and clinical applications | Genes Chromosomes and Cancer | 2018 | 155 |
| 9 | Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms | Blood | 2017 | 152 |
| 10 | Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 147 |
| 11 | Non-random karyotypic evolution in chronic myeloid leukemia | International Journal of Cancer | 1976 | 136 |
| 12 | Recurrent EWSR1-CREB3L1 Gene Fusions in Sclerosing Epithelioid Fibrosarcoma | American Journal of Surgical Pathology | 2014 | 132 |
| 13 | Chromosomes and cancer | Hereditas | 2009 | 129 |
| 14 | Cytogenetic aberrations in 188 benign and borderline adipose tissue tumors | Genes Chromosomes and Cancer | 1994 | 128 |
| 15 | Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney | Journal of Pathology | 2012 | 125 |
| 16 | Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 122 |
| 17 | Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes | Genes Chromosomes and Cancer | 2012 | 120 |
| 18 | Recurrent Rearrangement of the PHF1 Gene in Ossifying Fibromyxoid Tumors | American Journal of Pathology | 2012 | 119 |
| 19 | Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lymphomas | Genes Chromosomes and Cancer | 2004 | 114 |
| 20 | The molecular signature of MDS stem cells supports a stem-cell origin of 5q− myelodysplastic syndromes | Blood | 2007 | 107 |
| 21 | Gene fusions in soft tissue tumors: Recurrent and overlapping pathogenetic themes | Genes Chromosomes and Cancer | 2016 | 107 |
| 22 | Risk perception, screening practice and interest in genetic testing among unaffected men in families with hereditary prostate cancer | European Journal of Cancer | 2000 | 104 |
| 23 | Selective killing of candidate AML stem cells by antibody targeting of IL1RAP | Blood | 2013 | 102 |
| 24 | Pediatric T‐cell acute lymphoblastic leukemia | Genes Chromosomes and Cancer | 2017 | 101 |
| 25 | A glioma classification scheme based on coexpression modules of EGFR and PDGFRA | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 93 |
| 26 | Clustering of aberrations to specific chromosomes in human neoplasms: | Hereditas | 2009 | 92 |
| 27 | Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 92 |
| 28 | Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas | Genes Chromosomes and Cancer | 2014 | 91 |
| 29 | FANCMc.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor | Human Molecular Genetics | 2015 | 91 |
| 30 | Non-random chromosome changes in acute myeloid leukemia. Chromosome banding examination of 30 cases at diagnosis | International Journal of Cancer | 1976 | 87 |
| 31 | Multiple mechanisms of MYCN dysregulation in Wilms tumour | Oncotarget | 2015 | 85 |
| 32 | The DNA methylome of pediatric acute lymphoblastic leukemia | Human Molecular Genetics | 2009 | 83 |
| 33 | Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia | Journal of Experimental Medicine | 2014 | 79 |
| 34 | Cancer predictive value of cytogenetic markers used in occupational health surveillance programs: a report from an ongoing study by the European Study Group on Cytogenetic Biomarkers and Health | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1998 | 78 |
| 35 | Chromosome aberrations and micronuclei in bone marrow cells and peripheral blood lymphocytes in humans exposed to ethylene oxide | Hereditas | 2008 | 78 |
| 36 | Provision of genetic services in Europe: current practices and issues | European Journal of Human Genetics | 2003 | 77 |
| 37 | IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models | Blood | 2016 | 77 |
| 38 | FUS-CREB3L2/L1–Positive Sarcomas Show a Specific Gene Expression Profile with Upregulation of CD24 and FOXL1 | Clinical Cancer Research | 2011 | 75 |
| 39 | GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma | Nature Genetics | 2014 | 75 |
| 40 | Neuroblastoma patient‐derived orthotopic xenografts retain metastatic patterns and geno‐ and phenotypes of patient tumours | International Journal of Cancer | 2015 | 75 |
| 41 | Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells | Nature Genetics | 2017 | 75 |
| 42 | A Short History of Chromosome Rearrangements and Gene Fusions in Cancer | | 2015 | 75 |
| 43 | Gene fusion detection in formalin-fixed paraffin-embedded benign fibrous histiocytomas using fluorescence in situ hybridization and RNA sequencing | Laboratory Investigation | 2015 | 69 |
| 44 | Genetic and phenotypic dissection of 1q43q44 microdeletion syndrome and neurodevelopmental phenotypes associated with mutations in ZBTB18 and HNRNPU | Human Genetics | 2017 | 66 |
| 45 | Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 64 |
| 46 | Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations | Leukemia | 2010 | 61 |
| 47 | FN1–EGF gene fusions are recurrent in calcifying aponeurotic fibroma | Journal of Pathology | 2016 | 60 |
| 48 | Individuals with FANCM biallelic mutations do not develop Fanconi anemia, but show risk for breast cancer, chemotherapy toxicity and may display chromosome fragility | Genetics in Medicine | 2018 | 59 |
| 49 | Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer | Nature Communications | 2015 | 58 |
| 50 | Copy number defects of G1‐Cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis | Genes Chromosomes and Cancer | 2012 | 57 |
