| The Amber biomolecular simulation programs | Journal of Computational Chemistry | 2005 | 6.2K |
| Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis | Science | 2003 | 3.4K |
| Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 2.8K |
| A specific amyloid-beta protein assembly in the brain impairs memory | Nature | 2006 | 2.4K |
| Of mice and not men: differences between mouse and human immunology | Journal of Immunology | 2004 | 2.3K |
| Classification of papillomaviruses | Virology | 2004 | 2.2K |
| Mechanism of Molybdenum Nitrogenase | Chemical Reviews | 1996 | 1.4K |
| Structure of bacteriorhodopsin at 1.55 A resolution | Journal of Molecular Biology | 1999 | 1.3K |
| PI3K and cancer: lessons, challenges and opportunities | Nature Reviews Drug Discovery | 2014 | 1.1K |
| The PI3K Pathway in Human Disease | Cell | 2017 | 1K |
| Regulation of transcription by a protein methyltransferase | Science | 1999 | 987 |
| Molecular cloning and expression of a receptor for human tumor necrosis factor | Cell | 1990 | 934 |
| Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha | Nature | 2003 | 873 |
| Heme enzyme structure and function | Chemical Reviews | 2014 | 782 |
| Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers | Journal of Biological Chemistry | 2005 | 761 |
| Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases | Journal of Biological Chemistry | 2004 | 695 |
| A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility | Genetics | 1988 | 693 |
| Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs | Journal of Biological Chemistry | 1992 | 687 |
| X-ray emission spectroscopy evidences a central carbon in the nitrogenase iron-molybdenum cofactor | Science | 2011 | 659 |
| Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 656 |
| Structural classification of toxic amyloid oligomers | Journal of Biological Chemistry | 2008 | 622 |
| Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction | Journal of Biological Chemistry | 1999 | 602 |
| Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center | Cell | 1998 | 593 |
| Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268 | Journal of Neuroscience | 2001 | 586 |
| Crystal structure of horseradish peroxidase C at 2.15 A resolution | Nature Structural Biology | 1997 | 570 |
