| # | Title | Journal | Year | Citations |
|---|
| 1 | Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms | Drug Metabolism Reviews | 2004 | 511 |
| 2 | The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor | Cellular Signalling | 2007 | 142 |
| 3 | Nicotine promotes cell proliferation via α7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells | Toxicology and Applied Pharmacology | 2007 | 139 |
| 4 | Antitussive Activity ofStemonaAlkaloids fromStemona tuberosa | Planta Medica | 2003 | 129 |
| 5 | Role of Intestinal First-Pass Metabolism of Baicalein in its Absorption Process | Pharmaceutical Research | 2005 | 121 |
| 6 | Anti‐cancer therapy with TNFα and IFNγ: A comprehensive review | Cell Proliferation | 2018 | 119 |
| 7 | Relaxant effects of danshen aqueous extract and its constituent danshensu on rat coronary artery are mediated by inhibition of calcium channels | Vascular Pharmacology | 2007 | 115 |
| 8 | Involvement of UDP-Glucuronosyltransferases in the Extensive Liver and Intestinal First-Pass Metabolism of Flavonoid Baicalein | Pharmaceutical Research | 2006 | 112 |
| 9 | Pharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the Rat | Drug Metabolism and Disposition | 2008 | 111 |
| 10 | Simultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatography | Journal of Chromatography A | 1999 | 108 |
| 11 | Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta | Journal of Ethnopharmacology | 2007 | 107 |
| 12 | The angiogenic effects ofAngelica sinensis extract on HUVEC in vitro and zebrafish in vivo | Journal of Cellular Biochemistry | 2008 | 104 |
| 13 | Simultaneous Analysis of Seventeen Chemical Ingredients ofLigusticum chuanxiongby On-Line High Performance Liquid Chromatography-Diode Array Detector-Mass Spectrometry | Planta Medica | 2003 | 103 |
| 14 | Mechanistic study on the intestinal absorption and disposition of baicalein | European Journal of Pharmaceutical Sciences | 2007 | 100 |
| 15 | Chemistry and biological activities of naturally occurring phthalides | Studies in Natural Products Chemistry | 2005 | 99 |
| 16 | Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells | Biochemical and Biophysical Research Communications | 2009 | 99 |
| 17 | Focus on prostacyclin and its novel mimetics | Trends in Pharmacological Sciences | 1996 | 97 |
| 18 | Chromatographic analysis of Fritillaria isosteroidal alkaloids, the active ingredients of Beimu, the antitussive traditional Chinese medicinal herb | Journal of Chromatography A | 2001 | 93 |
| 19 | Potent contractile actions of prostanoid EP3‐receptor agonists on human isolated pulmonary artery | British Journal of Pharmacology | 1994 | 91 |
| 20 | Angiogenic effect of saponin extract from Panax notoginseng on HUVECs in vitro and zebrafish in vivo | Phytotherapy Research | 2009 | 88 |
| 21 | Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatography | Journal of Pharmaceutical and Biomedical Analysis | 2005 | 87 |
| 22 | Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation | Food and Chemical Toxicology | 2008 | 87 |
| 23 | Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG | Life Sciences | 2007 | 86 |
| 24 | Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells | Cancer Letters | 2009 | 84 |
| 25 | The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats | Toxicon | 1999 | 81 |
| 26 | Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin | Neuroscience Letters | 2006 | 81 |
| 27 | Identification of histone methylation multiplicities patterns in the brain of senescence-accelerated prone mouse 8 | Biogerontology | 2010 | 80 |
| 28 | Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells | Biochemical and Biophysical Research Communications | 2008 | 79 |
| 29 | Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high-performance liquid chromatography coupled with evaporative light scattering detection | Journal of Chromatography A | 2001 | 78 |
| 30 | The action of the NK1 tachykinin receptor antagonist, CP 99,994, in antagonizing the acute and delayed emesis induced by cisplatin in the ferret | British Journal of Pharmacology | 1996 | 77 |
| 31 | Potential New Antitumor Agents from an Innovative Combination of Demethylcantharidin, a Modified Traditional Chinese Medicine, with a Platinum Moiety | Journal of Medicinal Chemistry | 2001 | 77 |
| 32 | Deacetylclivorine: A Gender-Selective Metabolite of Clivorine Formed in Female Sprague-Dawley Rat Liver Microsomes | Drug Metabolism and Disposition | 2007 | 76 |
| 33 | Probiotic Lactobacillus rhamnosus GG enhances gastric ulcer healing in rats | European Journal of Pharmacology | 2007 | 75 |
| 34 | Opportunities for the replacement of animals in the study of nausea and vomiting | British Journal of Pharmacology | 2009 | 75 |
| 35 | PHARMACOKINETICS OF PROPOFOL IN CHILDREN | British Journal of Anaesthesia | 1990 | 73 |
| 36 | Mechanisms underlying the vasorelaxing effects of butylidenephthalide, an active constituent of Ligusticum chuanxiong, in rat isolated aorta | European Journal of Pharmacology | 2006 | 73 |
| 37 | The usefulness of the spontaneously hypertensive rat to model attention-deficit/hyperactivity disorder (ADHD) may be explained by the differential expression of dopamine-related genes in the brain | Neurochemistry International | 2007 | 71 |
| 38 | A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID‐activated gene | International Journal of Cancer | 2009 | 71 |
| 39 | Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways | Journal of Nutritional Biochemistry | 2010 | 71 |
| 40 | Salvianolic acid B, an aqueous component of danshen (Salvia miltiorrhiza), relaxes rat coronary artery by inhibition of calcium channels | European Journal of Pharmacology | 2006 | 70 |
| 41 | Traditional Chinese medicine for atopic eczema: PentaHerbs formula suppresses inflammatory mediators release from mast cells | Journal of Ethnopharmacology | 2008 | 70 |
| 42 | The effects of Danshen (Salvia miltiorrhiza) on pharmacokinetics and pharmacodynamics of warfarin in rats | European Journal of Drug Metabolism and Pharmacokinetics | 1992 | 67 |
| 43 | Genotoxic Pyrrolizidine Alkaloids — Mechanisms Leading to DNA Adduct Formation and Tumorigenicity | International Journal of Molecular Sciences | 2002 | 65 |
| 44 | Determination of hepatotoxic pyrrolizidine alkaloids by on-line high performance liquid chromatography mass spectrometry with an electrospray interface | | 1998 | 64 |
| 45 | Prostaglandin E2 potentiates the immunologically stimulated histamine release from human peripheral blood‐derived mast cells through EP1/EP3 receptors | Allergy: European Journal of Allergy and Clinical Immunology | 2006 | 64 |
| 46 | Pharmacological Evidence for Calcium Channel Inhibition by Danshen (Salvia miltiorrhiza) on Rat Isolated Femoral Artery | Journal of Cardiovascular Pharmacology | 2006 | 63 |
| 47 | Dihydrotanshinone, a lipophilic component of Salvia miltiorrhiza (danshen), relaxes rat coronary artery by inhibition of calcium channels | Journal of Ethnopharmacology | 2008 | 62 |
| 48 | Differential action of ondansetron and dexamethasone to modify cisplatin-induced acute and delayed kaolin consumption (“pica”) in rats | European Journal of Pharmacology | 2002 | 61 |
| 49 | Placental transfer of rosiglitazone in the first trimester of human pregnancy | Fertility and Sterility | 2005 | 61 |
| 50 | An interaction of ondansetron and dexamethasone antagonizing cisplatin‐induced acute and delayed emesis in the ferret | British Journal of Pharmacology | 1996 | 60 |
