| # | Title | Journal | Year | Citations |
|---|
|
| 1 | De novo mutations in schizophrenia implicate synaptic networks | Nature | 2014 | 1,533 |
| 2 | The lymphatic vasculature in disease | Nature Medicine | 2011 | 840 |
| 3 | Screening out irrelevant cell-based models of disease | Nature Reviews Drug Discovery | 2016 | 414 |
| 4 | RNA-Seq workflow: gene-level exploratory analysis and differential expression | F1000Research | 2015 | 319 |
| 5 | VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling | Nature Cell Biology | 2011 | 276 |
| 6 | Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene ( AUTS2 ) in the regulation of alcohol consumption | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 259 |
| 7 | Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia | Blood | 2017 | 202 |
| 8 | CKIα ablation highlights a critical role for p53 in invasiveness control | Nature | 2011 | 182 |
| 9 | Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors | Genes Chromosomes and Cancer | 2010 | 172 |
| 10 | Biological Basis of Therapeutic Lymphangiogenesis | Circulation | 2011 | 147 |
| 11 | CIDRE: an illumination-correction method for optical microscopy | Nature Methods | 2015 | 139 |
| 12 | Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation | Circulation | 2010 | 131 |
| 13 | Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization | Cancer Cell | 2010 | 120 |
| 14 | Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor | Blood | 2011 | 117 |
| 15 | CellTracker (not only) for dummies | Bioinformatics | 2016 | 111 |
| 16 | Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents Metastasis | Science Translational Medicine | 2011 | 107 |
| 17 | Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet | Molecular Metabolism | 2015 | 106 |
| 18 | Epismoker: A Robust Classifier to Determine Smoking Status from DNA Methylation Data | Epigenomics | 2019 | 100 |
| 19 | Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 87 |
| 20 | Advanced Cell Classifier: User-Friendly Machine-Learning-Based Software for Discovering Phenotypes in High-Content Imaging Data | Cell Systems | 2017 | 80 |
| 21 | Phenotypic Image Analysis Software Tools for Exploring and Understanding Big Image Data from Cell-Based Assays | Cell Systems | 2018 | 79 |
| 22 | Structural determinants of vascular endothelial growth factor-D receptor binding and specificity | Blood | 2011 | 78 |
| 23 | Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion | Developmental Cell | 2015 | 78 |
| 24 | Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer | European Urology | 2017 | 77 |
| 25 | A Single-Nucleotide Substitution Mutator Phenotype Revealed by Exome Sequencing of Human Colon Adenomas | Cancer Research | 2012 | 61 |
| 26 | Fibroblast Growth Factor Receptor 4 Regulates Tumor Invasion by Coupling Fibroblast Growth Factor Signaling to Extracellular Matrix Degradation | Cancer Research | 2010 | 49 |
| 27 | Angiopoietin-Like 4 Mediates PPAR Delta Effect on Lipoprotein Lipase-Dependent Fatty Acid Uptake but Not on Beta-Oxidation in Myotubes | PLoS ONE | 2012 | 47 |
| 28 | Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells | Cancer Research | 2013 | 42 |
| 29 | Interaction with ErbB4 Promotes Hypoxia-inducible Factor-1α Signaling | Journal of Biological Chemistry | 2012 | 41 |
| 30 | Perspectives on lymphangiogenesis and angiogenesis in cancer | Journal of Surgical Oncology | 2011 | 39 |
| 31 | Nucleus segmentation: towards automated solutions | Trends in Cell Biology | 2022 | 39 |
| 32 | Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support | Oncotarget | 2014 | 38 |
| 33 | Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets | Cell Chemical Biology | 2019 | 37 |
| 34 | Structural Genomic Variation as Risk Factor for Idiopathic Recurrent Miscarriage | Human Mutation | 2014 | 34 |
| 35 | Deletion of the Endothelial Bmx Tyrosine Kinase Decreases Tumor Angiogenesis and Growth | Cancer Research | 2012 | 32 |
| 36 | AnnotatorJ: an ImageJ plugin to ease hand annotation of cellular compartments | Molecular Biology of the Cell | 2020 | 32 |
| 37 | Patient-tailored design for selective co-inhibition of leukemic cell subpopulations | Science Advances | 2021 | 31 |
| 38 | Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke | Neurology | 2021 | 28 |
| 39 | Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations | Angiogenesis | 2013 | 25 |
| 40 | Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution | Nucleic Acids Research | 2013 | 23 |
| 41 | Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras‐driven lung tumours | Journal of Pathology | 2018 | 22 |
| 42 | Stanniocalcin-1 Hormone in Nonpreeclamptic and Preeclamptic Pregnancy: Clinical, Life-Style, and Genetic Modulators | Journal of Clinical Endocrinology and Metabolism | 2016 | 20 |
| 43 | 3D-Cell-Annotator: an open-source active surface tool for single-cell segmentation in 3D microscopy images | Bioinformatics | 2020 | 19 |
| 44 | Improved detection of differentially represented DNA barcodes for high‐throughput clonal phenomics | Molecular Systems Biology | 2020 | 18 |
| 45 | CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells | Stem Cell Reports | 2022 | 15 |
| 46 | A Longitudinal Study of Health Improvement in the Atlanta CHDWB Wellness Cohort | Journal of Personalized Medicine | 2014 | 13 |
| 47 | Identification of novel regulators of STAT3 activity | PLoS ONE | 2020 | 13 |
| 48 | Investigation of the Antihypertrophic and Antifibrotic Effects of Losartan in a Rat Model of Radiation-Induced Heart Disease | International Journal of Molecular Sciences | 2021 | 13 |
| 49 | Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism | Nucleic Acids Research | 2022 | 13 |
| 50 | Cell Type-Specific Arousal-Dependent Modulation of Thalamic Activity in the Lateral Geniculate Nucleus | Cerebral Cortex Communications | 2021 | 12 |
