# | Title | Journal | Year | Citations |
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1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
2 | A Syndrome produced by Diverse Nocuous Agents | Nature | 1936 | 2,544 |
3 | Increased Insulin Sensitivity and Obesity Resistance in Mice Lacking the Protein Tyrosine Phosphatase-1B Gene | Science | 1999 | 2,002 |
4 | eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation | Annual Review of Biochemistry | 1999 | 1,934 |
5 | Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA | Nature | 1988 | 1,896 |
6 | Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor | Cell | 1983 | 1,547 |
7 | Regulation of translation initiation by FRAP/mTOR | Genes and Development | 2001 | 1,363 |
8 | Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome | Nature Cell Biology | 2000 | 1,358 |
9 | Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function | Nature | 1994 | 1,192 |
10 | Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg | Cell | 1993 | 1,119 |
11 | Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins | Cell | 1986 | 1,060 |
12 | Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth | Neuron | 1994 | 1,054 |
13 | Pathways of chaperone-mediated protein folding in the cytosol | Nature Reviews Molecular Cell Biology | 2004 | 1,013 |
14 | Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap | Nature | 1990 | 920 |
15 | Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination | Nature Genetics | 2003 | 905 |
16 | Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization | Science | 2008 | 903 |
17 | XBP1, Downstream of Blimp-1, Expands the Secretory Apparatus and Other Organelles, and Increases Protein Synthesis in Plasma Cell Differentiation | Immunity | 2004 | 901 |
18 | The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC | Nature Structural and Molecular Biology | 2012 | 832 |
19 | Isolation and expression of a complementary DNA that confers multidrug resistance | Nature | 1986 | 800 |
20 | Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation | Cell | 1999 | 772 |
21 | Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus | Nature Medicine | 2000 | 742 |
22 | Target identification using drug affinity responsive target stability (DARTS) | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 710 |
23 | Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer | Cancer Cell | 2013 | 678 |
24 | splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3 | Cell | 1991 | 669 |
25 | Regulation of apoptosis by endoplasmic reticulum pathways | Oncogene | 2003 | 668 |
26 | Mechanisms of sodium pump regulation | American Journal of Physiology - Cell Physiology | 2000 | 655 |
27 | Statistical practice in high-throughput screening data analysis | Nature Biotechnology | 2006 | 644 |
28 | The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding Proteins | Molecular and Cellular Biology | 1995 | 643 |
29 | Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F. | Molecular and Cellular Biology | 1990 | 640 |
30 | Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP | Cell | 1997 | 635 |
31 | Molecular biology of bacterial bioluminescence | Microbiological Reviews | 1991 | 633 |
32 | RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation | Journal of Biological Chemistry | 2007 | 627 |
33 | Phosphatidylcholine translocase: A physiological role for the mdr2 gene | Cell | 1994 | 622 |
34 | Short RNAs Repress Translation after Initiation in Mammalian Cells | Molecular Cell | 2006 | 620 |
35 | Regulation of Protein Synthesis by Hypoxia via Activation of the Endoplasmic Reticulum Kinase PERK and Phosphorylation of the Translation Initiation Factor eIF2α | Molecular and Cellular Biology | 2002 | 606 |
36 | Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. | EMBO Journal | 1996 | 604 |
37 | Regulation of apoptosis by viral gene products | Journal of Virology | 1997 | 599 |
38 | Regulated Targeting of BAX to Mitochondria | Journal of Cell Biology | 1998 | 587 |
39 | The mRNA 5′ cap-binding protein eIF4E and control of cell growth | Current Opinion in Cell Biology | 1998 | 568 |
40 | Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2 | Molecular and Cellular Biology | 2004 | 566 |
41 | Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase | Science | 1992 | 556 |
42 | The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. | Journal of Experimental Medicine | 1995 | 556 |
43 | Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A. | EMBO Journal | 1992 | 555 |
44 | mTOR, translation initiation and cancer | Oncogene | 2006 | 552 |
45 | Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2 | Nature | 2010 | 548 |
46 | The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP | Cell | 2008 | 542 |
47 | Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E. | EMBO Journal | 1995 | 531 |
48 | La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate | Journal of Virology | 1993 | 514 |
49 | A roadmap for interpreting 13 C metabolite labeling patterns from cells | Current Opinion in Biotechnology | 2015 | 513 |
50 | RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer | Nature | 2014 | 506 |