| # | Title | Journal | Year | Citations |
|---|
| 1 | Regulation of the immune system by biodiversity from the natural environment: An ecosystem service essential to health | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 574 |
| 2 | Hygiene Hypothesis and Autoimmune Diseases | Clinical Reviews in Allergy and Immunology | 2012 | 323 |
| 3 | The global tuberculosis epidemic and progress in care, prevention, and research: an overview in year 3 of the End TB era | Lancet Respiratory Medicine,the | 2018 | 311 |
| 4 | New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects | Lancet Infectious Diseases, The | 2014 | 302 |
| 5 | High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial | Lancet Infectious Diseases, The | 2017 | 294 |
| 6 | Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies | Lancet Infectious Diseases, The | 2018 | 281 |
| 7 | A Dose-Ranging Trial to Optimize the Dose of Rifampin in the Treatment of Tuberculosis | American Journal of Respiratory and Critical Care Medicine | 2015 | 260 |
| 8 | Tuberculosis: advances and challenges in development of new diagnostics and biomarkers | Lancet Infectious Diseases, The | 2018 | 244 |
| 9 | Drug-resistant tuberculosis: time for visionary political leadership | Lancet Infectious Diseases, The | 2013 | 243 |
| 10 | Lockdown measures in response to COVID-19 in nine sub-Saharan African countries | BMJ Global Health | 2020 | 237 |
| 11 | Imaging in tuberculosis | International Journal of Infectious Diseases | 2015 | 210 |
| 12 | Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene | Perspectives in Public Health | 2016 | 206 |
| 13 | Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review | Lancet Respiratory Medicine,the | 2014 | 195 |
| 14 | Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD | Thorax | 2012 | 193 |
| 15 | Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study | Lancet Respiratory Medicine,the | 2013 | 184 |
| 16 | Microbial ‘old friends’, immunoregulation and socioeconomic status | Clinical and Experimental Immunology | 2014 | 165 |
| 17 | Eighteenth-century genomes show that mixed infections were common at time of peak tuberculosis in Europe | Nature Communications | 2015 | 165 |
| 18 | Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial | Lancet, The | 2019 | 156 |
| 19 | Tuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities | Journal of Infectious Diseases | 2012 | 154 |
| 20 | Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment | Lancet Respiratory Medicine,the | 2013 | 151 |
| 21 | The transmission of Mycobacterium tuberculosis in high burden settings | Lancet Infectious Diseases, The | 2016 | 149 |
| 22 | Drug-Resistant Tuberculosis—Current Dilemmas, Unanswered Questions, Challenges, and Priority Needs | Journal of Infectious Diseases | 2012 | 140 |
| 23 | The immune system of children: the key to understanding SARS-CoV-2 susceptibility? | The Lancet Child and Adolescent Health | 2020 | 132 |
| 24 | COVID-19—Zoonosis or Emerging Infectious Disease? | Frontiers in Public Health | 2020 | 104 |
| 25 | Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe | PLoS Pathogens | 2018 | 98 |
| 26 | Molecular Bacterial Load Assay, a Culture-Free Biomarker for Rapid and Accurate Quantification of Sputum Mycobacterium tuberculosis Bacillary Load during Treatment | Journal of Clinical Microbiology | 2011 | 97 |
| 27 | Uptake and yield of HIV testing and counselling among children and adolescents in sub‐Saharan Africa: a systematic review | Journal of the International AIDS Society | 2015 | 95 |
| 28 | Helsinki alert of biodiversity and health | Annals of Medicine | 2015 | 95 |
| 29 | Blood and sputum eosinophils in COPD; relationship with bacterial load | Respiratory Research | 2017 | 94 |
| 30 | Highly Reproducible Absolute Quantification of Mycobacterium tuberculosis Complex by Digital PCR | Analytical Chemistry | 2015 | 87 |
| 31 | The complex evolution of antibiotic resistance in Mycobacterium tuberculosis | International Journal of Infectious Diseases | 2015 | 82 |
| 32 | Hygiene and other early childhood influences on the subsequent function of the immune system | Brain Research | 2015 | 78 |
| 33 | ECIL-3 classical diagnostic procedures for the diagnosis of invasive fungal diseases in patients with leukaemia | Bone Marrow Transplantation | 2012 | 74 |
| 34 | Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay | BMJ Open | 2013 | 74 |
| 35 | The Late Arrival of Coronavirus Disease 2019 (COVID-19) in Africa: Mitigating Pan-continental Spread | Clinical Infectious Diseases | 2020 | 64 |
| 36 | Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs | British Medical Bulletin | 2016 | 63 |
| 37 | The Molecular Bacterial Load Assay Replaces Solid Culture for Measuring Early Bactericidal Response to Antituberculosis Treatment | Journal of Clinical Microbiology | 2014 | 62 |
| 38 | Effects of different antibiotic classes on airway bacteria in stable COPD using culture and molecular techniques: a randomised controlled trial | Thorax | 2015 | 61 |
| 39 | Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy | BMC Medicine | 2016 | 55 |
| 40 | From Easing Lockdowns to Scaling Up Community-based Coronavirus Disease 2019 Screening, Testing, and Contact Tracing in Africa—Shared Approaches, Innovations, and Challenges to Minimize Morbidity and Mortality | Clinical Infectious Diseases | 2021 | 54 |
| 41 | An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis | International Journal of Antimicrobial Agents | 2012 | 52 |
| 42 | Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N′-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercular Agents Effective against Multidrug-Resistant Mycobacteria | Journal of Medicinal Chemistry | 2016 | 51 |
| 43 | The Global Case-Fatality Rate of COVID-19 Has Been Declining Since May 2020 | American Journal of Tropical Medicine and Hygiene | 2021 | 51 |
| 44 | Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay | Thorax | 2020 | 49 |
| 45 | A migration-driven model for the historical spread of leprosy in medieval Eastern and Central Europe | Infection, Genetics and Evolution | 2015 | 48 |
| 46 | Effects of SARS-CoV-2 on Cardiovascular System: The Dual Role of Angiotensin-Converting Enzyme 2 (ACE2) as the Virus Receptor and Homeostasis Regulator-Review | International Journal of Molecular Sciences | 2021 | 48 |
| 47 | Nonsteroidal Antiinflammatory Drugs for Adjunctive Tuberculosis Treatment | Journal of Infectious Diseases | 2013 | 47 |
| 48 | Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries | JAMA Pediatrics | 2022 | 44 |
| 49 | 2-Hydroxy-substituted cinnamic acids and acetanilides are selective growth inhibitors of Mycobacterium tuberculosis | MedChemComm | 2014 | 43 |
| 50 | The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis | BMC Infectious Diseases | 2016 | 41 |
