| # | Title | Journal | Year | Citations |
|---|
|
| 1 | The Clinical Dementia Rating (CDR) | Neurology | 1993 | 8,127 |
| 2 | Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion | Science | 2011 | 5,177 |
| 3 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,451 |
| 4 | Cancer immunoediting: from immunosurveillance to tumor escape | Nature Immunology | 2002 | 4,412 |
| 5 | Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages | Nature Immunology | 2005 | 4,155 |
| 6 | EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 4,131 |
| 7 | Functional diversity of helper T lymphocytes | Nature | 1996 | 4,118 |
| 8 | Neoantigens in cancer immunotherapy | Science | 2015 | 3,966 |
| 9 | Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death | Nature | 1990 | 3,673 |
| 10 | HOW CELLS RESPOND TO INTERFERONS | Annual Review of Biochemistry | 1998 | 3,649 |
| 11 | Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death | Science | 2001 | 3,643 |
| 12 | A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease | Cell | 2017 | 3,574 |
| 13 | Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 | Nature Biotechnology | 2016 | 3,430 |
| 14 | Bone Resorption by Osteoclasts | Science | 2000 | 3,427 |
| 15 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 16 | Autophagy in immunity and inflammation | Nature | 2011 | 2,965 |
| 17 | The Immunological Synapse: A Molecular Machine Controlling T Cell Activation | Science | 1999 | 2,896 |
| 18 | The Immunobiology of Cancer Immunosurveillance and Immunoediting | Immunity | 2004 | 2,552 |
| 19 | The Three Es of Cancer Immunoediting | Annual Review of Immunology | 2004 | 2,486 |
| 20 | IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity | Nature | 2001 | 2,444 |
| 21 | In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse | Science | 1999 | 2,368 |
| 22 | Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression | Cell | 2015 | 2,288 |
| 23 | National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach | Acta Neuropathologica | 2012 | 2,114 |
| 24 | Innate lymphoid cells — a proposal for uniform nomenclature | Nature Reviews Immunology | 2013 | 2,108 |
| 25 | National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease | Alzheimer's and Dementia | 2012 | 2,089 |
| 26 | FcRn: the neonatal Fc receptor comes of age | Nature Reviews Immunology | 2007 | 1,945 |
| 27 | Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis | Cell | 2013 | 1,792 |
| 28 | Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody | Nature | 2020 | 1,778 |
| 29 | Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages | Nature Immunology | 2012 | 1,766 |
| 30 | Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens | Nature | 2014 | 1,762 |
| 31 | Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease | Science | 2010 | 1,760 |
| 32 | 2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines | Annals of Thoracic Surgery | 2011 | 1,756 |
| 33 | Natural Innate and Adaptive Immunity to Cancer | Annual Review of Immunology | 2011 | 1,747 |
| 34 | No evidence that carotenoid pigments boost either immune or antioxidant defenses in a songbird | Nature Communications | 2018 | 1,728 |
| 35 | Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature | Journal of Neuropathology and Experimental Neurology | 2012 | 1,663 |
| 36 | Microglia Function in the Central Nervous System During Health and Neurodegeneration | Annual Review of Immunology | 2017 | 1,636 |
| 37 | Innate Lymphoid Cells: 10 Years On | Cell | 2018 | 1,591 |
| 38 | Tangles and plaques in nondemented aging and ?preclinical? Alzheimer's disease | Annals of Neurology | 1999 | 1,583 |
| 39 | BCL-2 FAMILY: Regulators of Cell Death | Annual Review of Immunology | 1998 | 1,581 |
| 40 | Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway | Cell | 1996 | 1,555 |
| 41 | The lineage decisions of helper T cells | Nature Reviews Immunology | 2002 | 1,529 |
| 42 | Genetic regulation of osteoclast development and function | Nature Reviews Genetics | 2003 | 1,498 |
| 43 | Plasmacytoid dendritic cells in immunity | Nature Immunology | 2004 | 1,440 |
| 44 | Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer | Journal of Molecular Diagnostics | 2017 | 1,364 |
| 45 | A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells | Nature | 2008 | 1,363 |
| 46 | Mitochondrial DNA stress primes the antiviral innate immune response | Nature | 2015 | 1,342 |
| 47 | Interferons, immunity and cancer immunoediting | Nature Reviews Immunology | 2006 | 1,340 |
| 48 | Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains | Science | 1997 | 1,337 |
| 49 | Metabolic Pathways in Immune Cell Activation and Quiescence | Immunity | 2013 | 1,323 |
| 50 | TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model | Cell | 2015 | 1,305 |
