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Top Articles

#TitleJournalYearCitations
1Mechanism Of Cell Surface Activation Of 72-kDa Type IV CollagenaseJournal of Biological Chemistry19951,392
2SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human MacrophagesJournal of Biological Chemistry1989974
3H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.Journal of Biological Chemistry1988937
4SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophagesJournal of Biological Chemistry1989813
5A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1Molecular Cell2000794
6H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagenJournal of Biological Chemistry1988764
7Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitisJournal of Allergy and Clinical Immunology2012731
8Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic ItchCell2017692
9Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cellsJournal of Experimental Medicine2010662
10Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.Proceedings of the National Academy of Sciences of the United States of America1989547
11Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.Proceedings of the National Academy of Sciences of the United States of America1989534
12Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axisNature2018438
13Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitisJournal of Allergy and Clinical Immunology2013402
14Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysinJournal of Biological Chemistry1992377
15F3/Contactin Acts as a Functional Ligand for Notch during Oligodendrocyte MaturationCell2003332
16First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantationBlood2018307
17Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathwayInfection and Immunity1996307
18Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domainsCell1992305
19Loss of Kindlin-1, a Human Homolog of the Caenorhabditis elegans Actin–Extracellular-Matrix Linker Protein UNC-112, Causes Kindler SyndromeAmerican Journal of Human Genetics2003305
20Mutations in ABCA12 Underlie the Severe Congenital Skin Disease Harlequin IchthyosisAmerican Journal of Human Genetics2005302
21A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasisNature Genetics2003284
22γ-Secretase Functions through Notch Signaling to Maintain Skin Appendages but Is Not Required for Their Patterning or Initial MorphogenesisDevelopmental Cell2004282
23An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignanciesLeukemia2018282
24Lysyl Oxidase Is Required for Vascular and Diaphragmatic Development in MiceJournal of Biological Chemistry2003271
25Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal MicroenvironmentCancer Cell2009245
26Grading dermatologic adverse events of cancer treatments: The Common Terminology Criteria for Adverse Events Version 4.0Journal of the American Academy of Dermatology2012244
27Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2Journal of Biological Chemistry1993242
28Major role of nitrite-oxidizing bacteria in dark ocean carbon fixationScience2017229
29Growth Stimulation of Human Keratinocytes by Tissue Inhibitor of MetalloproteinasesJournal of Investigative Dermatology1991213
30Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic ItchImmunity2019213
31Target Selectivity of Vertebrate Notch ProteinsJournal of Biological Chemistry2006197
32Normal nonmetastatic human trophoblast cells share in vitro invasive properties of malignant cellsJournal of Cellular Physiology1988194
33Potentiation of Rifampicin and 5-Fluorocytosine as Antifungal Antibiotics by Amphotericin BProceedings of the National Academy of Sciences of the United States of America1972185
34Germline hypomorphic CARD11 mutations in severe atopic diseaseNature Genetics2017174
35Mechanisms of UV-Induced Inflammation.Journal of Investigative Dermatology1993172
36Human Skin Fibroblast Collagenase: Interaction with Substrate and InhibitorCollagen and Related Research1985153
37QUANTITATION AND IMMUNOCYTOCHEMICAL LOCALIZATION OF HUMAN SKIN COLLAGENASE IN BASAL CELL CARCINOMAJournal of Investigative Dermatology1977151
38Overlapping Genomic Sequences: A Treasure Trove of Single-Nucleotide PolymorphismsGenome Research1998151
39THE PREPARATION AND SOME PROPERTIES OF PURIFIED ANTIBODY SPECIFIC FOR THE 2,4-DINITROPHENYL GROUPJournal of Experimental Medicine1960150
40A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencingNature Communications2019147
41Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathologyJournal of Allergy and Clinical Immunology2014146
42Mohs Micrographic Surgery for Penile Cancer: Management and Long-Term FollowupJournal of Urology2007141
43A Subset of Methylated CpG Sites Differentiate Psoriatic from Normal SkinJournal of Investigative Dermatology2012138
44A Homogeneous, Ligase-Mediated DNA Diagnostic TestGenome Research1998137
45Defects In The Biochemistry Of Collagen In Diseases Of Connective TissueJournal of Investigative Dermatology1976136
46Alanine scanning mutagenesis and functional analysis of the fibronectin-like collagen-binding domain from human 92-kDa type IV collagenase.Journal of Biological Chemistry1992134
47Activation of 72-kDa Type IV Collagenase/Gelatinase by Normal Fibroblasts in Collagen Lattices Is Mediated by Integrin Receptors but Is Not Related to Lattice ContractionExperimental Cell Research1994133
48Fluorescence energy transfer detection as a homogeneous DNA diagnostic methodProceedings of the National Academy of Sciences of the United States of America1997133
49Increasing the Information Content of STS-Based Genome Maps: Identifying Polymorphisms in Mapped STSsGenomics1996132
50Analysis of Notch Function in Presomitic Mesoderm Suggests a γ-Secretase-Independent Role for Presenilins in Somite DifferentiationDevelopmental Cell2005132