| # | Title | Journal | Year | Citations |
|---|
| 1 | Analysis of protein-coding genetic variation in 60,706 humans | Nature | 2016 | 9,051 |
| 2 | An epigenetic biomarker of aging for lifespan and healthspan | Aging | 2018 | 1,552 |
| 3 | DNA methylation GrimAge strongly predicts lifespan and healthspan | Aging | 2019 | 1,128 |
| 4 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 5 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
| 6 | Gender Differences in the Regulation of Blood Pressure | Hypertension | 2001 | 986 |
| 7 | The genetic architecture of type 2 diabetes | Nature | 2016 | 952 |
| 8 | Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia | Journal of the American College of Cardiology | 2016 | 723 |
| 9 | Chronic Leptin Infusion Increases Arterial Pressure | Hypertension | 1998 | 636 |
| 10 | Mendelian randomization of blood lipids for coronary heart disease | European Heart Journal | 2015 | 567 |
| 11 | HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials | Lancet, The | 2015 | 562 |
| 12 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 13 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
| 14 | Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data | BMJ, The | 2014 | 528 |
| 15 | Sympathetic Neural Activation in Visceral Obesity | Circulation | 2002 | 475 |
| 16 | Exome-wide association study of plasma lipids in >300,000 individuals | Nature Genetics | 2017 | 470 |
| 17 | Functional and Structural Changes in the Kidney in the Early Stages of Obesity | Journal of the American Society of Nephrology: JASN | 2001 | 451 |
| 18 | Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction | American Journal of Physiology - Heart and Circulatory Physiology | 2008 | 432 |
| 19 | Loss-of-function mutations in SLC30A8 protect against type 2 diabetes | Nature Genetics | 2014 | 428 |
| 20 | Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals | PLoS Genetics | 2012 | 419 |
| 21 | Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies | Aging | 2018 | 406 |
| 22 | Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins | Journal of Biological Chemistry | 2010 | 399 |
| 23 | Inherited causes of clonal haematopoiesis in 97,691 whole genomes | Nature | 2020 | 376 |
| 24 | Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease | Science Translational Medicine | 2015 | 375 |
| 25 | Guidelines for experimental models of myocardial ischemia and infarction | American Journal of Physiology - Heart and Circulatory Physiology | 2018 | 372 |
| 26 | Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes | Nature Genetics | 2018 | 356 |
| 27 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 28 | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis | PLoS Medicine | 2017 | 341 |
| 29 | Obesity, kidney dysfunction and hypertension: mechanistic links | Nature Reviews Nephrology | 2019 | 336 |
| 30 | Obesity, hypertension, and chronic kidney disease | International Journal of Nephrology and Renovascular Disease | 2014 | 335 |
| 31 | The landscape of recombination in African Americans | Nature | 2011 | 319 |
| 32 | Obesity hypertension: role of leptin and sympathetic nervous system | American Journal of Hypertension | 2001 | 310 |
| 33 | Testosterone Exacerbates Hypertension and Reduces Pressure-Natriuresis in Male Spontaneously Hypertensive Rats | Hypertension | 1998 | 287 |
| 34 | Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks | American Journal of Human Genetics | 2014 | 287 |
| 35 | Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity | Nature Genetics | 2018 | 286 |
| 36 | Obesity-induced hypertension. Renal function and systemic hemodynamics. | Hypertension | 1993 | 281 |
| 37 | IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation | Basic Research in Cardiology | 2017 | 278 |
| 38 | Assembly of a pan-genome from deep sequencing of 910 humans of African descent | Nature Genetics | 2019 | 276 |
| 39 | Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction | Translational Research | 2018 | 275 |
| 40 | Placental Insufficiency Leads to Development of Hypertension in Growth-Restricted Offspring | Hypertension | 2003 | 259 |
| 41 | Temporal neutrophil polarization following myocardial infarction | Cardiovascular Research | 2016 | 253 |
| 42 | Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation | Nature Genetics | 2022 | 250 |
| 43 | Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls | Nature | 2019 | 248 |
| 44 | Gender Differences in Development of Hypertension in Spontaneously Hypertensive Rats | Hypertension | 2000 | 246 |
| 45 | Renal Denervation Attenuates the Sodium Retention and Hypertension Associated With Obesity | Hypertension | 1995 | 246 |
| 46 | Reduced Uterine Perfusion Pressure During Pregnancy in the Rat Is Associated With Increases in Arterial Pressure and Changes in Renal Nitric Oxide | Hypertension | 2001 | 241 |
| 47 | Effects of polycythemia and anemia on cardiac output and other circulatory factors | American Journal of Physiology | 1959 | 240 |
| 48 | Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci | American Journal of Human Genetics | 2012 | 227 |
| 49 | Guidelines for measuring cardiac physiology in mice | American Journal of Physiology - Heart and Circulatory Physiology | 2018 | 220 |
| 50 | Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium | PLoS ONE | 2013 | 219 |
