avg. Impact Factor

Most Cited Articles of Department of Physiology and Biophysics

Analysis of protein-coding genetic variation in 60,706 humansNature20166.9K
Gender differences in the regulation of blood pressureHypertension2001798
The genetic architecture of type 2 diabetesNature2016704
An epigenetic biomarker of aging for lifespan and healthspanAging2018658
The kidney, hypertension, and obesityHypertension2003634
Chronic leptin infusion increases arterial pressureHypertension1998590
Obesity-induced hypertension: interaction of neurohumoral and renal mechanismsCirculation Research2015571
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypesNature Genetics2018536
Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe HypercholesterolemiaJournal of the American College of Cardiology2016458
DNA methylation GrimAge strongly predicts lifespan and healthspanAging2019424
Sympathetic neural activation in visceral obesityCirculation2002422
Mendelian randomization of blood lipids for coronary heart diseaseEuropean Heart Journal2015417
Rare and low-frequency coding variants alter human adult heightNature2017412
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trialsLancet, The2015409
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant dataBMJ, The2014406
Functional and structural changes in the kidney in the early stages of obesityJournal of the American Society of Nephrology: JASN2001366
Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunctionAmerican Journal of Physiology - Heart and Circulatory Physiology2008357
Loss-of-function mutations in SLC30A8 protect against type 2 diabetesNature Genetics2014351
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individualsPLoS Genetics2012326
Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortinsJournal of Biological Chemistry2010325
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in MexicoNature2014323
Exome-wide association study of plasma lipids in >300,000 individualsNature Genetics2017310
Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunctionHypertension2001298
Mechanisms of obesity-associated cardiovascular and renal diseaseAmerican Journal of the Medical Sciences2002276
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed ProgramNature2021268