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| Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling | Nature Genetics | 2001 | 767 |
| Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 543 |
| Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex | Science | 2001 | 501 |
| The signal recognition particle | Annual Review of Biochemistry | 2001 | 485 |
| Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 456 |
| A conserved regulatory system for aging | Cell | 2001 | 429 |
| Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly | Nature Cell Biology | 2001 | 377 |
| Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms | Nature | 2001 | 377 |
| Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions | Science | 2001 | 354 |
| Defining brain wiring patterns and mechanisms through gene trapping in mice | Nature | 2001 | 347 |
| Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction | Science | 2001 | 340 |
| Zebrafish genetics and vertebrate heart formation | Nature Reviews Genetics | 2001 | 323 |
| ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions | Bioinformatics | 2001 | 316 |
| An unusual pathway of excitation energy deactivation in carotenoids: singlet-to-triplet conversion on an ultrafast timescale in a photosynthetic antenna | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 293 |
| Switch-based mechanism of kinesin motors | Nature | 2001 | 281 |
| Two checkpoint complexes are independently recruited to sites of DNA damage in vivo | Genes and Development | 2001 | 278 |
| Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 273 |
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| Dynamic regulation of axon guidance | Nature Neuroscience | 2001 | 260 |
| How membranes shape protein structure | Journal of Biological Chemistry | 2001 | 255 |
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| UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish | Science | 2001 | 242 |
| casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish | Genes and Development | 2001 | 237 |
