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| Effects of angiogenesis inhibitors on multistage carcinogenesis in mice | Science | 1999 | 866 |
| Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 | Nature | 1999 | 714 |
| The maximal affinity of ligands | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 709 |
| Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis | Genes and Development | 1999 | 708 |
| A structural change in the kinesin motor protein that drives motility | Nature | 1999 | 652 |
| A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor | Nature | 1999 | 592 |
| Kin I kinesins are microtubule-destabilizing enzymes | Cell | 1999 | 584 |
| Copper binding to the prion protein: structural implications of four identical cooperative binding sites | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 485 |
| Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs | Cell | 1999 | 477 |
| Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 451 |
| Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel | Journal of Molecular Biology | 1999 | 428 |
| Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1 | Nature | 1999 | 426 |
| A comparison between the sulfhydryl reductants tris(2-carboxyethyl)phosphine and dithiothreitol for use in protein biochemistry | Analytical Biochemistry | 1999 | 367 |
| A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies | Trends in Pharmacological Sciences | 1999 | 339 |
| I5M: 3D widefield light microscopy with better than 100 nm axial resolution | Journal of Microscopy | 1999 | 337 |
| Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae | Molecular Biology of the Cell | 1999 | 328 |
| Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans | Science | 1999 | 322 |
| Nuclear-receptor ligands and ligand-binding domains | Annual Review of Biochemistry | 1999 | 301 |
| Regulation of nuclear localization: a key to a door | Annual Review of Cell and Developmental Biology | 1999 | 267 |
| A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response | Cell | 1999 | 261 |
| Transmissible and genetic prion diseases share a common pathway of neurodegeneration | Nature | 1999 | 260 |
| Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein | Molecular Biology of the Cell | 1999 | 255 |
| Crystal structure of human heme oxygenase-1 | Nature Structural Biology | 1999 | 254 |
| SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation | Nature Cell Biology | 1999 | 252 |
