| # | Title | Journal | Year | Citations |
|---|
| 1 | C-reactive protein: a critical update | Journal of Clinical Investigation | 2003 | 1,673 |
| 2 | A proposed system for the nomenclature of hepatitis C viral genotypes | Hepatology | 1994 | 962 |
| 3 | Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study | Clinical Endocrinology | 2000 | 843 |
| 4 | Natural History and Outcome in Systemic AA Amyloidosis | New England Journal of Medicine | 2007 | 817 |
| 5 | Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells | Journal of Cell Science | 2000 | 682 |
| 6 | Misdiagnosis of Hereditary Amyloidosis as AL (Primary) Amyloidosis | New England Journal of Medicine | 2002 | 621 |
| 7 | Targeting C-reactive protein for the treatment of cardiovascular disease | Nature | 2006 | 621 |
| 8 | Measurement of Lipid Peroxidation | Free Radical Research | 1998 | 619 |
| 9 | Measurement of Plasma Hydroperoxide Concentrations by the Ferrous Oxidation-Xylenol Orange Assay in Conjunction with Triphenylphosphine | Analytical Biochemistry | 1994 | 613 |
| 10 | Amyloidosis | Annual Review of Medicine | 2006 | 557 |
| 11 | Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein | Lancet, The | 2001 | 520 |
| 12 | Effect of alcohol consumption on systemic markers of inflammation | Lancet, The | 2001 | 496 |
| 13 | Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis | Nature | 2002 | 495 |
| 14 | “Vasocrine” signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease | Lancet, The | 2005 | 478 |
| 15 | Progression of Coronary Atherosclerosis Is Associated with a Common Genetic Variant of the Human Stromelysin-1 Promoter Which Results in Reduced Gene Expression | Journal of Biological Chemistry | 1996 | 437 |
| 16 | Does malnutrition in utero determine diabetes and coronary heart disease in adulthood? Results from the Leningrad siege study, a cross sectional study | BMJ: British Medical Journal | 1997 | 430 |
| 17 | Muscle Protein Synthesis Measured by Stable Isotope Techniques in Man: The Effects of Feeding and Fasting | Clinical Science | 1982 | 418 |
| 18 | The metabolic fate of dietary polyphenols in humans | Free Radical Biology and Medicine | 2002 | 416 |
| 19 | Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics | Kidney International | 2008 | 415 |
| 20 | Physical Activity and Hemostatic and Inflammatory Variables in Elderly Men | Circulation | 2002 | 407 |
| 21 | Making and working with hydrogen sulfide | Free Radical Biology and Medicine | 2009 | 388 |
| 22 | Outcome in systemic AL amyloidosis in relation to changes in concentration of circulating free immunoglobulin light chains following chemotherapy | British Journal of Haematology | 2003 | 370 |
| 23 | Incubation Phase of Acute Hepatitis B in Man: Dynamic of Cellular Immune Mechanisms | Hepatology | 2000 | 359 |
| 24 | TheStreptococcuspneumoniaeCapsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms | Infection and Immunity | 2010 | 356 |
| 25 | Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase | British Journal of Pharmacology | 1996 | 354 |
| 26 | Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection | Gastroenterology | 1999 | 331 |
| 27 | Endothelial Mitochondria | Circulation Research | 2007 | 331 |
| 28 | A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active crohn's disease | Gastroenterology | 2001 | 327 |
| 29 | Hypoxia promotes fibrogenesis in human renal fibroblasts | Kidney International | 2000 | 319 |
| 30 | Common Promoter Variant in Cyclooxygenase-2 Represses Gene Expression | Arteriosclerosis, Thrombosis, and Vascular Biology | 2002 | 312 |
| 31 | Evaluation and Management of the Cardiac Amyloidosis | Journal of the American College of Cardiology | 2007 | 306 |
| 32 | Presence of a newly described human DNA virus (TTV) in patients with liver disease | Lancet, The | 1998 | 297 |
| 33 | Scleroderma: from cell and molecular mechanisms to disease models | Trends in Immunology | 2005 | 283 |
| 34 | Distribution of factor VIII mRNA and antigen in human liver and other tissues | Nature | 1985 | 275 |
| 35 | Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells | Journal of Cell Science | 2000 | 275 |
| 36 | Terlipressin for norepinephrine-resistant septic shock | Lancet, The | 2002 | 274 |
| 37 | The hypothalamic-pituitary-gonadal axis: immune function and autoimmunity | Journal of Endocrinology | 2003 | 269 |
| 38 | The relationship between the thyroid gland and the liver | QJM - Monthly Journal of the Association of Physicians | 2002 | 265 |
| 39 | Elevated Levels of Authentic Plasma Hydroperoxides in NIDDM | Diabetes | 1995 | 244 |
| 40 | Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis. | Heart | 1995 | 234 |
| 41 | Randomised trial of safety and efficacy of immediate postoperative enteral feeding in patients undergoing gastrointestinal resection | BMJ: British Medical Journal | 1996 | 232 |
| 42 | Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant? | Biochemical Pharmacology | 1995 | 224 |
| 43 | Cloning and Targeted Deletion of the Mouse Fetuin Gene | Journal of Biological Chemistry | 1997 | 222 |
| 44 | The 4G/5G Genetic Polymorphism in the Promoter of the Plasminogen Activator Inhibitor-1 (PAI-1) Gene Is Associated with Differences in Plasma PAI-1 Activity but not with Risk of Myocardial Infarction in the ECTIM Study | Thrombosis and Haemostasis | 1995 | 214 |
| 45 | Safety and efficacy of risk-adapted cyclophosphamide, thalidomide, and dexamethasone in systemic AL amyloidosis | Blood | 2007 | 212 |
| 46 | Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie | Nature Medicine | 2001 | 206 |
| 47 | Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization* | Clinical Endocrinology | 2001 | 205 |
| 48 | C-reactive protein and cardiovascular disease: new insights from an old molecule | QJM - Monthly Journal of the Association of Physicians | 2003 | 199 |
| 49 | Connective tissue growth factor: A new and important player in the pathogenesis of fibrosis | Current Rheumatology Reports | 2002 | 196 |
| 50 | 3-Methylhistidine Excretion and the Urinary 3-Methylhistidine/Creatinine Ratio Are Poor Indicators of Skeletal Muscle Protein Breakdown | Clinical Science | 1983 | 195 |
