# | Title | Journal | Year | Citations |
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1 | Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans | Immunity | 2010 | 648 |
2 | Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans | Nature Immunology | 2007 | 561 |
3 | An integrated expression atlas of miRNAs and their promoters in human and mouse | Nature Biotechnology | 2017 | 456 |
4 | Evidence that reactive oxygen species do not mediate NF- B activation | EMBO Journal | 2003 | 363 |
5 | Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 | Journal of Experimental Medicine | 2003 | 353 |
6 | A Biomimetic Mussel‐Inspired ε‐Poly‐l‐lysine Hydrogel with Robust Tissue‐Anchor and Anti‐Infection Capacity | Advanced Functional Materials | 2017 | 342 |
7 | Regulation of Matrix Metalloproteinases (MMP-2, -3, -9, and -13) by Interleukin-1 and Interleukin-6 in Mouse Calvaria: Association of MMP Induction with Bone Resorption* | Endocrinology | 1998 | 341 |
8 | The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors | Nature Immunology | 2007 | 300 |
9 | The LPS receptor (CD14) links innate immunity with Alzheimer's disease | FASEB Journal | 2004 | 290 |
10 | Saccharomyces cerevisiae‐ and Candida albicans‐Derived Mannan Induced Production of Tumor Necrosis Factor Alpha by Human Monocytes in a CD14‐ and Toll‐Like Receptor 4‐Dependent Manner | Microbiology and Immunology | 2002 | 263 |
11 | Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages | Biochemical Pharmacology | 2003 | 259 |
12 | Gene delivery by combination of novel liposomal bubbles with perfluoropropane and ultrasound | Journal of Controlled Release | 2007 | 225 |
13 | Characterization of β-Glucan Recognition Site on C-Type Lectin, Dectin 1 | Infection and Immunity | 2004 | 223 |
14 | A Myelin Galactolipid, Sulfatide, Is Essential for Maintenance of Ion Channels on Myelinated Axon But Not Essential for Initial Cluster Formation | Journal of Neuroscience | 2002 | 218 |
15 | Natural products reveal cancer cell dependence on oxysterol-binding proteins | Nature Chemical Biology | 2011 | 215 |
16 | Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine | Cell Host and Microbe | 2015 | 215 |
17 | Total Synthesis of Aryl C-Glycoside Natural Products: Strategies and Tactics | Chemical Reviews | 2018 | 207 |
18 | DNA strand-breaking activity and mutagenicity of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one (DDMP), a Maillard reaction product of glucose and glycine | Mutation Research - Genetic Toxicology and Environmental Mutagenesis | 1997 | 199 |
19 | FANTOM5 CAGE profiles of human and mouse samples | Scientific Data | 2017 | 195 |
20 | Delivery of siRNA to the brain using a combination of nose-to-brain delivery and cell-penetrating peptide-modified nano-micelles | Biomaterials | 2013 | 194 |
21 | Gangliosides contribute to stability of paranodal junctions and ion channel clusters in myelinated nerve fibers | Glia | 2007 | 189 |
22 | Cancer gene therapy by IL-12 gene delivery using liposomal bubbles and tumoral ultrasound exposure | Journal of Controlled Release | 2010 | 187 |
23 | Antitumor .BETA.-Glucan from the Cultured Fruit Body of Agaricus blazei. | Biological and Pharmaceutical Bulletin | 2001 | 183 |
24 | Hypoglycemic Effects of Turmeric (Curcuma longa L. Rhizomes) on Genetically Diabetic KK-Ay Mice | Biological and Pharmaceutical Bulletin | 2005 | 175 |
25 | Potent estrogen agonists based on carborane as a hydrophobic skeletal structure | Chemistry and Biology | 2001 | 172 |
26 | Difference in Effective Dosage of Genistein on Bone and Uterus in Ovariectomized Mice | Biochemical and Biophysical Research Communications | 2000 | 164 |
27 | An Essential Role of Cytosolic Phospholipase A2α in Prostaglandin E2–mediated Bone Resorption Associated with Inflammation | Journal of Experimental Medicine | 2003 | 164 |
28 | Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs | Bioorganic and Medicinal Chemistry Letters | 1997 | 158 |
29 | Synthetic Methods for Fluorinated Olefins | European Journal of Organic Chemistry | 2011 | 156 |
30 | One-step preparation of rifampicin/poly(lactic-co-glycolic acid) nanoparticle-containing mannitol microspheres using a four-fluid nozzle spray drier for inhalation therapy of tuberculosis | Journal of Controlled Release | 2009 | 154 |
31 | Fe3O4 nanoparticle-supported Cu(ii)-β-cyclodextrin complex as a magnetically recoverable and reusable catalyst for the synthesis of symmetrical biaryls and 1,2,3-triazoles from aryl boronic acids | Green Chemistry | 2013 | 151 |
32 | DNA-fiber EPR study of the orientation of Cu(II) complexes of 1,10-phenanthroline and its derivatives bound to DNA: mono(phenanthroline)-copper(II) and its ternary complexes with amino acids | Journal of Inorganic Biochemistry | 2002 | 150 |
33 | Blood vessels of human islets of Langerhans are surrounded by a double basement membrane | Diabetologia | 2008 | 147 |
34 | Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy | International Journal of Pharmaceutics | 1996 | 146 |
35 | Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes | Annals of the Rheumatic Diseases | 2016 | 144 |
36 | Catalytic Enantioselective Synthesis of Atropisomeric Indoles with an NC Chiral Axis | Chemistry - A European Journal | 2010 | 143 |
37 | Structure-Activity Relationship of (1.RAR.3)-.BETA.-D-Glucans in the Induction of Cytokine Production from Macrophages, in Vitro. | Biological and Pharmaceutical Bulletin | 1995 | 142 |
38 | DNA Damage by Fasicularin | Journal of the American Chemical Society | 2005 | 142 |
39 | Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles | Journal of Controlled Release | 2008 | 134 |
40 | Effective gene delivery with novel liposomal bubbles and ultrasonic destruction technology | International Journal of Pharmaceutics | 2008 | 133 |
41 | Nobiletin restoring β-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats | Neuroscience Letters | 2006 | 130 |
42 | Cell-Penetrating Peptide-Modified Block Copolymer Micelles Promote Direct Brain Delivery via Intranasal Administration | Pharmaceutical Research | 2011 | 130 |
43 | Plasma Membrane-bound Tissue Inhibitor of Metalloproteinases (TIMP)-2 Specifically Inhibits Matrix Metalloproteinase 2 (Gelatinase A) Activated on the Cell Surface | Journal of Biological Chemistry | 1998 | 127 |
44 | Nobiletin, a Citrus Flavonoid That Improves Memory Impairment, Rescues Bulbectomy-Induced Cholinergic Neurodegeneration in Mice | Journal of Pharmacological Sciences | 2007 | 124 |
45 | Delivery of siRNA into the cytoplasm by liposomal bubbles and ultrasound | Journal of Controlled Release | 2008 | 124 |
46 | Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells | Cancer Research | 2002 | 124 |
47 | Solubilization of yeast cell-wall β-(1→3)-d-glucan by sodium hypochlorite oxidation and dimethyl sulfoxide extraction | Carbohydrate Research | 1999 | 123 |
48 | Total Synthesis of (−)-Incarvilline, (+)-Incarvine C, and (−)-Incarvillateine | Journal of the American Chemical Society | 2004 | 119 |
49 | Cytotoxic Activities and Structure-Cytotoxic Relationships of Steroidal Saponins. | Biological and Pharmaceutical Bulletin | 2001 | 118 |
50 | Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications | Molecules | 2011 | 115 |