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top-articles
Life Sciences Division
399
(top 1%)
papers
38.2K
(top 0.1%)
citations
93
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h
-index
187
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409
all documents
40.4K
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4.4K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Nature
2000
8,977
2
Complete Structure of the 11-Subunit Bovine Mitochondrial Cytochrome bc1 Complex
1998
1,150
3
Structural basis of water-specific transport through the AQP1 water channel
Nature
2001
1,058
4
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
Molecular Oncology
2007
872
5
Matrix Metalloproteinase Stromelysin-1 Triggers a Cascade of Molecular Alterations That Leads to Stable Epithelial-to-Mesenchymal Conversion and a Premalignant Phenotype in Mammary Epithelial Cells
Journal of Cell Biology
1997
757
6
Complete subunit architecture of the proteasome regulatory particle
Nature
2012
542
7
Mechanical Properties of the Red Cell Membrane in Relation to Molecular Structure and Genetic Defects
Annual Review of Biophysics and Biomolecular Structure
1994
485
8
Negative Feedback Regulation of TGF- Signaling by the SnoN Oncoprotein
Science
1999
480
9
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
Nature
2008
467
10
Redox-mediated activation of latent transforming growth factor-beta 1.
Molecular Endocrinology
1996
465
11
Context, tissue plasticity, and cancer
Cancer Cell
2005
464
12
SATB1 targets chromatin remodelling to regulate genes over long distances
Nature
2002
456
13
Replicative Senescence: An Old Lives' Tale?
Cell
1996
438
14
Erythroblastic islands: niches for erythropoiesis
Blood
2008
415
15
'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns
Genome Biology
2000
392
16
Mammary gland development: cell fate specification, stem cells and the microenvironment
Development (Cambridge)
2015
343
17
Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.
Journal of Clinical Investigation
1994
343
18
Evidence for a stem cell hierarchy in the adult human breast
Journal of Cell Biology
2007
331
19
Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β‐amyloid
Annals of Neurology
2013
320
20
The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells
Development (Cambridge)
2001
317
21
Defective Transcription-Coupled Repair of Oxidative Base Damage in Cockayne Syndrome Patients from XP Group G
Science
1997
304
22
TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation
Nature Cell Biology
2001
297
23
Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell-Cycle G2/M Progression
Developmental Cell
2014
292
24
Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung
Journal of Applied Physiology
1995
271
25
Protein composition determines the anti-atherogenic properties of HDL in transgenic mice
Nature
1993
268
26
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
BMC Cancer
2008
254
27
Cloning of mice to six generations
Nature
2000
242
28
Microenvironmental Regulators of Tissue Structure and Function Also Regulate Tumor Induction and Progression: The Role of Extracellular Matrix and Its Degrading Enzymes
Cold Spring Harbor Symposia on Quantitative Biology
2005
242
29
Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic Instability
Radiation Research
2001
240
30
Conformational switching of the 26S proteasome enables substrate degradation
Nature Structural and Molecular Biology
2013
227
31
Targeting TACE-dependent EGFR ligand shedding in breast cancer
Journal of Clinical Investigation
2007
224
32
Protein 4.1R-dependent multiprotein complex: New insights into the structural organization of the red blood cell membrane
Proceedings of the National Academy of Sciences of the United States of America
2008
221
33
Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low‐dose γ‐irradiation
1
FASEB Journal
1997
215
34
Non-random distribution of DNA double-strand breaks induced by particle irradiation
International Journal of Radiation Biology
1996
213
35
Ski and SnoN: negative regulators of TGF-β signaling
Current Opinion in Genetics and Development
2004
206
36
Heterogeneity of plasma low-density lipoproteins and atherosclerosis risk
Current Opinion in Lipidology
1994
204
37
Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski
Cell
2002
200
38
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN
Genes and Development
2001
197
39
CD147 is a regulatory subunit of the -secretase complex in Alzheimer's disease amyloid -peptide production
Proceedings of the National Academy of Sciences of the United States of America
2005
186
40
Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: joining of correct and incorrect ends.
Proceedings of the National Academy of Sciences of the United States of America
1995
184
41
Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma
Journal of Cell Science
1995
184
42
SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic Cells
Developmental Cell
2009
183
43
Targeting the tumor microenvironment
Frontiers in Bioscience - Landmark
2007
181
44
Clusters of DNA Damage Induced by Ionizing Radiation: Formation of Short DNA Fragments. II. Experimental Detection
Radiation Research
1996
178
45
Rodent carcinogens: setting priorities
Science
1992
175
46
Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model
Differentiation
1998
173
47
Suppression of Mammary Epithelial Cell Differentiation by the Helix-Loop-Helix Protein Id-1
Molecular and Cellular Biology
1995
172
48
The relevance of dose-fractionation in tomography of radiation-sensitive specimens
Ultramicroscopy
1995
164
49
A simple method for obtaining cross-term-free images for diffusion anisotropy studies in NMR microimaging
Magnetic Resonance in Medicine
1991
163
50
The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/β-catenin pathway
Oncogene
2009
163
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