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Top Articles

#TitleJournalYearCitations
1Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingNature20008,977
2Complete Structure of the 11-Subunit Bovine Mitochondrial Cytochrome bc1 ComplexNature19981,150
3Structural basis of water-specific transport through the AQP1 water channelNature20011,058
4The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expressionMolecular Oncology2007872
5Matrix Metalloproteinase Stromelysin-1 Triggers a Cascade of Molecular Alterations That Leads to Stable Epithelial-to-Mesenchymal Conversion and a Premalignant Phenotype in Mammary Epithelial CellsJournal of Cell Biology1997757
6Complete subunit architecture of the proteasome regulatory particleNature2012542
7Mechanical Properties of the Red Cell Membrane in Relation to Molecular Structure and Genetic DefectsAnnual Review of Biophysics and Biomolecular Structure1994485
8Negative Feedback Regulation of TGF- Signaling by the SnoN OncoproteinScience1999480
9SATB1 reprogrammes gene expression to promote breast tumour growth and metastasisNature2008467
10Redox-mediated activation of latent transforming growth factor-beta 1.Molecular Endocrinology1996465
11Context, tissue plasticity, and cancerCancer Cell2005464
12SATB1 targets chromatin remodelling to regulate genes over long distancesNature2002456
13Replicative Senescence: An Old Lives' Tale?Cell1996438
14Erythroblastic islands: niches for erythropoiesisBlood2008415
15'Gene shaving' as a method for identifying distinct sets of genes with similar expression patternsGenome Biology2000392
16Mammary gland development: cell fate specification, stem cells and the microenvironmentDevelopment (Cambridge)2015343
17Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.Journal of Clinical Investigation1994343
18Evidence for a stem cell hierarchy in the adult human breastJournal of Cell Biology2007331
19Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β‐amyloidAnnals of Neurology2013320
20The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cellsDevelopment (Cambridge)2001317
21Defective Transcription-Coupled Repair of Oxidative Base Damage in Cockayne Syndrome Patients from XP Group GScience1997304
22TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradationNature Cell Biology2001297
23Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell-Cycle G2/M ProgressionDevelopmental Cell2014292
24Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lungJournal of Applied Physiology1995271
25Protein composition determines the anti-atherogenic properties of HDL in transgenic miceNature1993268
26Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalitiesBMC Cancer2008254
27Cloning of mice to six generationsNature2000242
28Microenvironmental Regulators of Tissue Structure and Function Also Regulate Tumor Induction and Progression: The Role of Extracellular Matrix and Its Degrading EnzymesCold Spring Harbor Symposia on Quantitative Biology2005242
29Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic InstabilityRadiation Research2001240
30Conformational switching of the 26S proteasome enables substrate degradationNature Structural and Molecular Biology2013227
31Targeting TACE-dependent EGFR ligand shedding in breast cancerJournal of Clinical Investigation2007224
32Protein 4.1R-dependent multiprotein complex: New insights into the structural organization of the red blood cell membraneProceedings of the National Academy of Sciences of the United States of America2008221
33Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low‐dose γ‐irradiation 1FASEB Journal1997215
34Non-random distribution of DNA double-strand breaks induced by particle irradiationInternational Journal of Radiation Biology1996213
35Ski and SnoN: negative regulators of TGF-β signalingCurrent Opinion in Genetics and Development2004206
36Heterogeneity of plasma low-density lipoproteins and atherosclerosis riskCurrent Opinion in Lipidology1994204
37Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein SkiCell2002200
38Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNGenes and Development2001197
39CD147 is a regulatory subunit of the  -secretase complex in Alzheimer's disease amyloid  -peptide productionProceedings of the National Academy of Sciences of the United States of America2005186
40Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: joining of correct and incorrect ends.Proceedings of the National Academy of Sciences of the United States of America1995184
41Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinomaJournal of Cell Science1995184
42SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic CellsDevelopmental Cell2009183
43Targeting the tumor microenvironmentFrontiers in Bioscience - Landmark2007181
44Clusters of DNA Damage Induced by Ionizing Radiation: Formation of Short DNA Fragments. II. Experimental DetectionRadiation Research1996178
45Rodent carcinogens: setting prioritiesScience1992175
46Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination modelDifferentiation1998173
47Suppression of Mammary Epithelial Cell Differentiation by the Helix-Loop-Helix Protein Id-1Molecular and Cellular Biology1995172
48The relevance of dose-fractionation in tomography of radiation-sensitive specimensUltramicroscopy1995164
49A simple method for obtaining cross-term-free images for diffusion anisotropy studies in NMR microimagingMagnetic Resonance in Medicine1991163
50The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/β-catenin pathwayOncogene2009163