| # | Title | Journal | Year | Citations |
|---|
| 1 | Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes | Nature Biotechnology | 2019 | 216 |
| 2 | Duration of Influenza Vaccine Effectiveness: A Systematic Review, Meta-analysis, and Meta-regression of Test-Negative Design Case-Control Studies | Journal of Infectious Diseases | 2018 | 105 |
| 3 | Empiric Piperacillin-Tazobactam versus Carbapenems in the Treatment of Bacteraemia Due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae | PLoS ONE | 2016 | 104 |
| 4 | A Concise Review of the Epidemiology and Diagnostics of Rickettsioses: Rickettsia and Orientia spp | Journal of Clinical Microbiology | 2018 | 103 |
| 5 | Prevalence of Healthcare-Associated Infections and Antimicrobial Use Among Adult Inpatients in Singapore Acute-Care Hospitals: Results From the First National Point Prevalence Survey | Clinical Infectious Diseases | 2017 | 97 |
| 6 | Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population | Scientific Reports | 2016 | 87 |
| 7 | Neuraminidase inhibitors, superinfection and corticosteroids affect survival of influenza patients | European Respiratory Journal | 2015 | 83 |
| 8 | Virus-specific T lymphocytes home to the skin during natural dengue infection | Science Translational Medicine | 2015 | 83 |
| 9 | Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus | PLoS ONE | 2016 | 79 |
| 10 | Do antibody responses to the influenza vaccine persist year-round in the elderly? A systematic review and meta-analysis | Vaccine | 2017 | 78 |
| 11 | Challenges in Dengue Fever in the Elderly: Atypical Presentation and Risk of Severe Dengue and Hospita-Acquired Infection | PLoS Neglected Tropical Diseases | 2014 | 77 |
| 12 | Malaria after international travel: a GeoSentinel analysis, 2003–2016 | Malaria Journal | 2017 | 74 |
| 13 | Safety and clinical outcomes of carbapenem de-escalation as part of an antimicrobial stewardship programme in an ESBL-endemic setting | Journal of Antimicrobial Chemotherapy | 2015 | 69 |
| 14 | Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever | PLoS Neglected Tropical Diseases | 2016 | 69 |
| 15 | Clinical and Molecular Epidemiology of Carbapenem-Resistant Enterobacteriaceae Among Adult Inpatients in Singapore | Clinical Infectious Diseases | 2017 | 62 |
| 16 | CAMERA2 – combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial | Trials | 2016 | 61 |
| 17 | Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority trial | Lancet, The | 2017 | 61 |
| 18 | Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27 | Journal of Antimicrobial Chemotherapy | 2018 | 56 |
| 19 | Diabetes, cardiac disorders and asthma as risk factors for severe organ involvement among adult dengue patients: A matched case-control study | Scientific Reports | 2017 | 55 |
| 20 | Population Pharmacokinetics of Polymyxin B | Clinical Pharmacology and Therapeutics | 2018 | 55 |
| 21 | Increased Serum Hyaluronic Acid and Heparan Sulfate in Dengue Fever: Association with Plasma Leakage and Disease Severity | Scientific Reports | 2017 | 50 |
| 22 | An inventory of supranational antimicrobial resistance surveillance networks involving low- and middle-income countries since 2000 | Journal of Antimicrobial Chemotherapy | 2018 | 47 |
| 23 | NK cells are activated and primed for skin-homing during acute dengue virus infection in humans | Nature Communications | 2019 | 46 |
| 24 | Multidrug-resistant and extensively drug-resistant Gram-negative prosthetic joint infections: Role of surgery and impact of colistin administration | International Journal of Antimicrobial Agents | 2019 | 46 |
| 25 | Progress and Challenges towards Point-of-Care Diagnostic Development for Dengue | Journal of Clinical Microbiology | 2017 | 43 |
| 26 | Dengue in the elderly: a review | Expert Review of Anti-Infective Therapy | 2017 | 42 |
| 27 | Longitudinal Study of Cellular and Systemic Cytokine Signatures to Define the Dynamics of a Balanced Immune Environment During Disease Manifestation in Zika Virus–Infected Patients | Journal of Infectious Diseases | 2018 | 40 |
| 28 | Pharmacokinetic/Pharmacodynamic Determinants of Vancomycin Efficacy in Enterococcal Bacteremia | Antimicrobial Agents and Chemotherapy | 2018 | 39 |
| 29 | Potential Harm of Prophylactic Platelet Transfusion in Adult Dengue Patients | PLoS Neglected Tropical Diseases | 2016 | 37 |
| 30 | Current management of severe dengue infection | Expert Review of Anti-Infective Therapy | 2017 | 35 |
| 31 | Early clinical and laboratory risk factors of intensive care unit requirement during 2004–2008 dengue epidemics in Singapore: a matched case–control study | BMC Infectious Diseases | 2014 | 33 |
| 32 | Risk factors for concurrent bacteremia in adult patients with dengue | Journal of Microbiology, Immunology and Infection | 2017 | 32 |
| 33 | Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity | MSphere | 2018 | 32 |
| 34 | Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients | Clinical and Translational Immunology | 2019 | 32 |
| 35 | Development of standard clinical endpoints for use in dengue interventional trials | PLoS Neglected Tropical Diseases | 2018 | 29 |
| 36 | Individual and Population Trajectories of Influenza Antibody Titers Over Multiple Seasons in a Tropical Country | American Journal of Epidemiology | 2018 | 27 |
| 37 | Metformin Use and Severe Dengue in Diabetic Adults | Scientific Reports | 2018 | 26 |
| 38 | Environmental colonization and onward clonal transmission of carbapenem-resistant Acinetobacter baumannii (CRAB) in a medical intensive care unit: the case for environmental hygiene | Antimicrobial Resistance and Infection Control | 2018 | 26 |
| 39 | A Sensitive Method for Detecting Zika Virus Antigen in Patients’ Whole-Blood Specimens as an Alternative Diagnostic Approach | Journal of Infectious Diseases | 2017 | 25 |
| 40 | Serum metabolome changes in adult patients with severe dengue in the critical and recovery phases of dengue infection | PLoS Neglected Tropical Diseases | 2018 | 25 |
| 41 | Factors influencing seasonal influenza vaccination uptake among health care workers in an adult tertiary care hospital in Singapore: A cross-sectional survey | American Journal of Infection Control | 2019 | 25 |
| 42 | Effective transfer of a 47 kb NDM-1-positive plasmid amongAcinetobacterspecies | Journal of Antimicrobial Chemotherapy | 2015 | 24 |
| 43 | A formative research-guided educational intervention to improve the knowledge and attitudes of seniors towards influenza and pneumococcal vaccinations | Vaccine | 2017 | 24 |
| 44 | Implementation hurdles of an interactive, integrated, point-of-care computerised decision support system for hospital antibiotic prescription | International Journal of Antimicrobial Agents | 2016 | 23 |
| 45 | Medical and psychosocial factors associated with antibiotic prescribing in primary care: survey questionnaire and factor analysis | British Journal of General Practice | 2017 | 22 |
| 46 | Contacts of healthcare workers, patients and visitors in general wards in Singapore | Epidemiology and Infection | 2017 | 22 |
| 47 | Comparison of Diabetic and Non-diabetic Human Leukocytic Responses to Different Capsule Types of Klebsiella pneumoniae Responsible for Causing Pyogenic Liver Abscess | Frontiers in Cellular and Infection Microbiology | 2017 | 22 |
| 48 | Epidemiological risk factors for adult dengue in Singapore: an 8-year nested test negative case control study | BMC Infectious Diseases | 2016 | 21 |
| 49 | Length of stay an important mediator of hospital-acquired methicillin-resistant Staphylococcus aureus | Epidemiology and Infection | 2016 | 21 |
| 50 | Association Between Increased Vascular Nitric Oxide Bioavailability and Progression to Dengue Hemorrhagic Fever in Adults | Journal of Infectious Diseases | 2015 | 17 |
