| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | The Genetic Landscape of a Cell | Science | 2010 | 1,937 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Proximal events in Wnt signal transduction | Nature Reviews Molecular Cell Biology | 2009 | 982 |
| 5 | BIND: the Biomolecular Interaction Network Database | Nucleic Acids Research | 2003 | 969 |
| 6 | Osteopontin | Critical Reviews in Oral Biology and Medicine | 2000 | 933 |
| 7 | BIND--The Biomolecular Interaction Network Database | Nucleic Acids Research | 2001 | 842 |
| 8 | Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map | Nature | 2007 | 806 |
| 9 | Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone | Cell | 2005 | 729 |
| 10 | New Tools Provide New Insights in NMR Studies of Protein Dynamics | Science | 2006 | 720 |
| 11 | Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system | Nature | 2013 | 689 |
| 12 | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser | Nature | 2015 | 683 |
| 13 | Mechanisms of regulation of the Na+/H+ exchanger | Journal of Membrane Biology | 1986 | 681 |
| 14 | Non-coding RNA: what is functional and what is junk? | Frontiers in Genetics | 2015 | 602 |
| 15 | Intracellular Localization of Liver Sugar Nucleotide Glycoprotein Glycosyltransferases in a Golgi-rich Fraction | Journal of Biological Chemistry | 1970 | 598 |
| 16 | A Co-Evolution Theory of the Genetic Code | Proceedings of the National Academy of Sciences of the United States of America | 1975 | 595 |
| 17 | Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways | Nature Biotechnology | 2004 | 584 |
| 18 | Pi-Pi contacts are an overlooked protein feature relevant to phase separation | ELife | 2018 | 571 |
| 19 | Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) gene | Genomics | 1991 | 560 |
| 20 | Calnexin: a membrane-bound chaperone of the endoplasmic reticulum | Trends in Biochemical Sciences | 1994 | 535 |
| 21 | The integrated landscape of driver genomic alterations in glioblastoma | Nature Genetics | 2013 | 524 |
| 22 | Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis | Molecular and Cellular Biology | 2003 | 505 |
| 23 | Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis | Journal of Cell Biology | 2000 | 489 |
| 24 | Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 485 |
| 25 | Pathways of O-glycan biosynthesis in cancer cells | Biochimica Et Biophysica Acta - General Subjects | 1999 | 483 |
| 26 | Quantitative dynamics and binding studies of the 20S proteasome by NMR | Nature | 2007 | 472 |
| 27 | Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch | Nature | 2015 | 471 |
| 28 | A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins | Journal of Biomolecular NMR | 1999 | 461 |
| 29 | A Call for Systematic Research on Solute Carriers | Cell | 2015 | 457 |
| 30 | The TGFbeta Superfamily Signaling Pathway | Wiley Interdisciplinary Reviews: Developmental Biology | 2013 | 450 |
| 31 | The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix | Environmental Microbiology | 2012 | 447 |
| 32 | Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl | Frontiers in Microbiology | 2011 | 432 |
| 33 | Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress | Nature Cell Biology | 2012 | 431 |
| 34 | In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells | Immunity | 2010 | 425 |
| 35 | The Molecular Chaperone Calnexin Binds Glc1Man9GlcNAc2 Oligosaccharide as an Initial Step in Recognizing Unfolded Glycoproteins | Journal of Biological Chemistry | 1995 | 415 |
| 36 | Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications | Journal of Biological Chemistry | 2016 | 402 |
| 37 | Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase | Science | 2008 | 401 |
| 38 | Heteroplasmic mtDNA mutation (T----G) at 8993 can cause Leigh disease when the percentage of abnormal mtDNA is high | American Journal of Human Genetics | 1992 | 391 |
| 39 | Endoplasmic Reticulum Stress: Signaling the Unfolded Protein Response | Physiology | 2007 | 388 |
| 40 | Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 381 |
| 41 | Regulation of Chromosome Replication | Annual Review of Biochemistry | 2000 | 373 |
| 42 | The pH of the Secretory Pathway: Measurement, Determinants, and Regulation | Physiology | 2004 | 371 |
| 43 | Mitochondria-Penetrating Peptides | Chemistry and Biology | 2008 | 367 |
| 44 | Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor | Nature Genetics | 1996 | 365 |
| 45 | Cell-penetrating peptides as delivery vehicles for biology and medicine | Organic and Biomolecular Chemistry | 2008 | 363 |
| 46 | Non-random Distribution of Amino Acids in the Transmembrane Segments of Human Type I Single Span Membrane Proteins | Journal of Molecular Biology | 1993 | 361 |
| 47 | Regulation of MHC class I transport by the molecular chaperone, calnexin (p88, IP90) | Science | 1994 | 360 |
| 48 | ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy | Autophagy | 2012 | 358 |
| 49 | Axonal Transport Enables Neuron-to-Neuron Propagation of Human Coronavirus OC43 | Journal of Virology | 2018 | 355 |
| 50 | Biosynthetic Controls That Determine the Branching and Microheterogeneity of Protein-Bound Oligosaccharides | Advances in Experimental Medicine and Biology | 1986 | 355 |
