| # | Title | Journal | Year | Citations |
|---|
| 1 | Histological grading and staging of chronic hepatitis | Journal of Hepatology | 1995 | 4,685 |
| 2 | Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology | Canadian Journal of Gastroenterology & Hepatology | 2005 | 2,711 |
| 3 | Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4 | Science | 1995 | 2,587 |
| 4 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 5 | Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma | Thyroid | 2015 | 1,738 |
| 6 | Fatty liver hepatitis (steatohepatitis) and obesity: An autopsy study with analysis of risk factors | Hepatology | 1990 | 1,072 |
| 7 | PD-L1 Immunohistochemistry Assays for Lung Cancer: Results from Phase 1 of the Blueprint PD-L1 IHC Assay Comparison Project | Journal of Thoracic Oncology | 2017 | 1,067 |
| 8 | Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent | Science | 1986 | 1,057 |
| 9 | Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration | Acta Neuropathologica | 2007 | 978 |
| 10 | Cancer immunotherapy: the beginning of the end of cancer? | BMC Medicine | 2016 | 908 |
| 11 | Myocardial infarction accelerates atherosclerosis | Nature | 2012 | 874 |
| 12 | Mammary Analogue Secretory Carcinoma of Salivary Glands, Containing the ETV6-NTRK3 Fusion Gene: A Hitherto Undescribed Salivary Gland Tumor Entity | American Journal of Surgical Pathology | 2010 | 857 |
| 13 | The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism | JAMA Surgery | 2016 | 840 |
| 14 | Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans | CRC Critical Reviews in Toxicology | 1983 | 834 |
| 15 | New principle for the analysis of chemical carcinogenesis | Nature | 1976 | 829 |
| 16 | Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta | Science | 1995 | 810 |
| 17 | Pathogenetic mechanisms in thyroid follicular-cell neoplasia | Nature Reviews Cancer | 2006 | 797 |
| 18 | Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer | Cancer Discovery | 2018 | 676 |
| 19 | micronodular transpormation (nodular regenerative hyperplasia) of the liver: A report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules | Hepatology | 1990 | 594 |
| 20 | PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project | Journal of Thoracic Oncology | 2018 | 589 |
| 21 | Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy | Nature Genetics | 1998 | 499 |
| 22 | A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer | Journal of Thoracic and Cardiovascular Surgery | 2011 | 484 |
| 23 | Novel YAP1‐TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma | Genes Chromosomes and Cancer | 2013 | 463 |
| 24 | Error in the determination of tryptophan by the method of Denkla and Dewey. A revised procedure | Analytical Biochemistry | 1974 | 436 |
| 25 | Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome | Nature Genetics | 1993 | 423 |
| 26 | Active Surveillance of Small Renal Masses: Progression Patterns of Early Stage Kidney Cancer | European Urology | 2011 | 422 |
| 27 | Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial | Clinical Cancer Research | 2018 | 414 |
| 28 | Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation | Journal of Thoracic and Cardiovascular Surgery | 2003 | 402 |
| 29 | Human brain dopamine receptors in children and aging adults | Synapse | 1987 | 396 |
| 30 | Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma | Nature Genetics | 2009 | 391 |
| 31 | Overview of the 2022 WHO Classification of Thyroid Neoplasms | Endocrine Pathology | 2022 | 388 |
| 32 | MSH2 deficient mice are viable and susceptible to lymphoid tumours | Nature Genetics | 1995 | 366 |
| 33 | Evidence for multi-site closure of the neural tube in humans | American Journal of Medical Genetics Part A | 1993 | 364 |
| 34 | Initiation of chemical carcinogenesis requires cell proliferation | Nature | 1978 | 361 |
| 35 | Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer | Gynecologic Oncology | 2011 | 342 |
| 36 | Techniques, Safety and Accuracy of Sampling of Renal Tumors by Fine Needle Aspiration and Core Biopsy | Journal of Urology | 2007 | 333 |
| 37 | Outcomes of Small Renal Mass Needle Core Biopsy, Nondiagnostic Percutaneous Biopsy, and the Role of Repeat Biopsy | European Urology | 2011 | 331 |
| 38 | The pathogenesis of pituitary tumours | Nature Reviews Cancer | 2002 | 327 |
| 39 | High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C | Hepatology | 2003 | 324 |
| 40 | Stranger in a strange land: The pathogenesis of saphenous vein graft stenosis with emphasis on structural and functional differences between veins and arteries | Progress in Cardiovascular Diseases | 1991 | 307 |
| 41 | Enteroendocrine localization of GLP-2 receptor expression in humans and rodents | Gastroenterology | 2000 | 297 |
| 42 | Low etiologic fraction for high-risk human papillomavirus in oral cavity squamous cell carcinomas | Oral Oncology | 2013 | 292 |
| 43 | The diabetic syndrome of the ?BB? Wistar rat: Possible relevance to Type 1 (insulin-dependent) diabetes in man | Diabetologia | 1982 | 283 |
| 44 | p53 Expression in Pituitary Adenomas and Carcinomas: Correlation with Invasiveness and Tumor Growth Fractions | Neurosurgery | 1996 | 269 |
| 45 | How Important Is Removal of the Parametrium at Surgery for Carcinoma of the Cervix? | Gynecologic Oncology | 2002 | 269 |
| 46 | Growth Hormone-Releasing Hormone-Producing Tumors: Clinical, Biochemical, and Morphological Manifestations* | Endocrine Reviews | 1988 | 265 |
| 47 | Prophylactic mesalamine treatment decreases postoperative recurrence of Crohn's disease | Gastroenterology | 1995 | 265 |
| 48 | Identification of driver genes in hepatocellular carcinoma by exome sequencing | Hepatology | 2013 | 264 |
| 49 | Development and validation of a histological index for UC | Gut | 2017 | 264 |
| 50 | Norepinephrine in chronic paranoid schizophrenia: above-normal levels in limbic forebrain | Science | 1978 | 258 |
