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#TitleJournalYearCitations
1Structural Simplification of Natural ProductsChemical Reviews2019157
2Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor AgentsJournal of Medicinal Chemistry2015156
3New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological EvaluationsJournal of Medicinal Chemistry2012146
4New Lead Structures in Antifungal Drug DiscoveryCurrent Medicinal Chemistry2011141
5State-of-the-art strategies for targeting protein–protein interactions by small-molecule inhibitorsChemical Society Reviews2015132
6Rapid Identification of Keap1–Nrf2 Small-Molecule Inhibitors through Structure-Based Virtual Screening and Hit-Based Substructure SearchJournal of Medicinal Chemistry2014127
7Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor AgentsJournal of Medicinal Chemistry2010122
8ADMET evaluation in drug discovery: 15. Accurate prediction of rat oral acute toxicity using relevance vector machine and consensus modelingJournal of Cheminformatics2016102
9Design, Synthesis, and Antihepatitis B Virus Activities of Novel 2-Pyridone DerivativesJournal of Medicinal Chemistry201094
10Meeting Organocatalysis with Drug Discovery: Asymmetric Synthesis of 3,3′-Spirooxindoles Fused with Tetrahydrothiopyrans as Novel p53-MDM2 InhibitorsOrganic Letters201677
11Divergent Cascade Construction of Skeletally Diverse “Privileged” Pyrazole‐Derived Molecular ArchitecturesEuropean Journal of Organic Chemistry201567
12Quinine-thiourea catalyzed enantioselective hydrophosphonylation of trifluoromethyl 2(1H)-quinazolinonesChemical Communications201360
13Small Molecules Simultaneously Inhibiting p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs): Discovery of Novel Multitargeting Antitumor AgentsJournal of Medicinal Chemistry201859
14Design and Synthesis of Cyclopropylamide Analogues of Combretastatin-A4 as Novel Microtubule-Stabilizing AgentsJournal of Medicinal Chemistry201358
15Effects of hydrogen-rich water on depressive-like behavior in miceScientific Reports201657
16Fragment Informatics and Computational Fragment‐Based Drug Design: An Overview and UpdateMedicinal Research Reviews201356
17Chlorin p6-Based Water-Soluble Amino Acid Derivatives as Potent Photosensitizers for Photodynamic TherapyJournal of Medicinal Chemistry201653
18Updated Research and Applications of Small Molecule Inhibitors of Keap1-Nrf2 Protein-Protein Interaction: a ReviewCurrent Medicinal Chemistry201453
19Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14α-demethylase (CYP51) of fungiBioorganic and Medicinal Chemistry Letters200649
20Structural simplification: an efficient strategy in lead optimizationActa Pharmaceutica Sinica B201949
21Scaffold Hopping of Natural Product Evodiamine: Discovery of a Novel Antitumor Scaffold with Excellent Potency against Colon CancerJournal of Medicinal Chemistry202047
22Discovery of Novel Fungal Lanosterol 14α-Demethylase (CYP51)/Histone Deacetylase Dual Inhibitors to Treat Azole-Resistant CandidiasisJournal of Medicinal Chemistry202045
23Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal CancerJournal of Medicinal Chemistry202043
24Thymoquinone Blocks pSer/pThr Recognition by Plk1 Polo-Box Domain As a Phosphate MimicACS Chemical Biology201342
25Synthesis of novel triazole derivatives as inhibitors of cytochrome P450 14α-demethylase (CYP51)European Journal of Medicinal Chemistry200741
26Facile Construction of Structurally Diverse Thiazolidinedione-Derived Compounds via Divergent Stereoselective Cascade Organocatalysis and Their Biological Exploratory StudiesACS Combinatorial Science201341
27New Strategies in the Discovery of Novel Non-Camptothecin Topoisomerase I InhibitorsCurrent Medicinal Chemistry201140
28Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) InfectionsJournal of Medicinal Chemistry201640
29Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with potent antitumor activityActa Pharmaceutica Sinica B202038
30Drug Repurposing of Haloperidol: Discovery of New Benzocyclane Derivatives as Potent Antifungal Agents against Cryptococcosis and CandidiasisACS Infectious Diseases202035
31Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant CandidiasisJournal of Medicinal Chemistry202135
32Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditisFree Radical Biology and Medicine201832
33Novel conformationally restricted triazole derivatives with potent antifungal activityEuropean Journal of Medicinal Chemistry201030
34Chemical Composition and Antidiabetic Activity of Opuntia Milpa Alta ExtractsChemistry and Biodiversity201029
35Synthesis and anti-tumor activity of novel ethyl 3-aryl-4-oxo-3,3a,4,6-tetrahydro-1H-furo[3,4-c]pyran-3a-carboxylatesBioorganic and Medicinal Chemistry Letters201129
36Synthesis of novel 2, 5-dihydrofuran derivatives and evaluation of their anticancer activityEuropean Journal of Medicinal Chemistry201229
37Design and synthesis of novel 2′-hydroxy group substituted 2-pyridone derivatives as anticancer agentsEuropean Journal of Medicinal Chemistry201327
38Strategies in the discovery of novel antifungal scaffoldsFuture Medicinal Chemistry201627
39Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistryEuropean Journal of Medicinal Chemistry201226
40Synthesis of spiro-tetrahydrothiopyran-oxindoles by Michael–aldol cascade reactions: discovery of potential P53-MDM2 inhibitors with good antitumor activityOrganic and Biomolecular Chemistry201825
41Facile Assembly of Chiral Tetrahydrothiopyrans Containing Four Consecutive Stereocenters via an Organocatalytic Enantioselective Michael–Michael CascadeOrganic Letters201424
42Organocatalytic Asymmetric Synthesis of Spiro‐Tetrahydrothiophene Oxindoles Bearing Four Contiguous Stereocenters by One‐Pot Michael–Henry‐Cascade–Rearrangement ReactionsChemistry - A European Journal201824
43Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal MeningitisJournal of Medicinal Chemistry201924
44Natural Product Evodiamine with Borate Trigger Unit: Discovery of Potent Antitumor Agents against Colon CancerACS Medicinal Chemistry Letters202024
45Synthesis and antifungal activities in vitro of novel pyrazino [2,1-a] isoquinolin derivativesBioorganic and Medicinal Chemistry Letters201023
46Total synthesis and structure–activity relationships of new echinocandin-like antifungal cyclolipohexapeptidesEuropean Journal of Medicinal Chemistry201223
47Construction of a three-dimensional pharmacophore for Bcl-2 inhibitors by flexible docking and the multiple copy simultaneous search methodBioorganic and Medicinal Chemistry200722
48Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicansEuropean Journal of Medicinal Chemistry202222
49Design, synthesis, and in vitro photodynamic activities of benzochloroporphyrin derivatives as tumor photosensitizersBioorganic and Medicinal Chemistry Letters200821
50Improving the Potency of Cancer Immunotherapy by Dual Targeting of IDO1 and DNAChemMedChem201820