| # | Title | Journal | Year | Citations |
|---|
| 1 | Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer | Molecular Cancer | 2014 | 840 |
| 2 | LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1 | Cancer Research | 2016 | 436 |
| 3 | Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression | BMC Cancer | 2013 | 389 |
| 4 | The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer | BMC Cancer | 2013 | 351 |
| 5 | Long Noncoding RNA ANRIL Promotes Non–Small Cell Lung Cancer Cell Proliferation and Inhibits Apoptosis by Silencing KLF2 and P21 Expression | Molecular Cancer Therapeutics | 2015 | 344 |
| 6 | Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a | Oncotarget | 2014 | 338 |
| 7 | Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer | Tumor Biology | 2014 | 265 |
| 8 | EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promote s NSCLC cell proliferation and metastasis by affecting the epithelial–mesenchymal transition | Cell Death and Disease | 2014 | 222 |
| 9 | Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts | Molecular Cancer | 2017 | 216 |
| 10 | A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1 | Genome Biology | 2018 | 216 |
| 11 | Label-Free Quantitative Detection of Tumor-Derived Exosomes through Surface Plasmon Resonance Imaging | Analytical Chemistry | 2014 | 211 |
| 12 | Long Noncoding RNA PVT1 Promotes Non–Small Cell Lung Cancer Cell Proliferation through Epigenetically Regulating LATS2 Expression | Molecular Cancer Therapeutics | 2016 | 206 |
| 13 | Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer | Chinese Journal of Cancer | 2011 | 200 |
| 14 | AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma | Oncogene | 2011 | 200 |
| 15 | Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2 | Molecular Cancer | 2015 | 197 |
| 16 | Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition | Molecular Cancer | 2014 | 193 |
| 17 | STAT3-induced lncRNA HAGLROS overexpression contributes to the malignant progression of gastric cancer cells via mTOR signal-mediated inhibition of autophagy | Molecular Cancer | 2018 | 189 |
| 18 | Tumor-Associated Macrophages Recruit CCR6+ Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice | PLoS ONE | 2011 | 182 |
| 19 | Resveratrol-loaded polymeric micelles protect cells from Aβ-induced oxidative stress | International Journal of Pharmaceutics | 2009 | 173 |
| 20 | Long non-coding RNAs in anti-cancer drug resistance | Oncotarget | 2017 | 173 |
| 21 | MicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5 | BMC Cancer | 2012 | 161 |
| 22 | Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer | Molecular Therapy | 2017 | 147 |
| 23 | Enhanced growth inhibition effect of Resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels | Colloids and Surfaces B: Biointerfaces | 2009 | 143 |
| 24 | Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells | Cell Death and Disease | 2016 | 142 |
| 25 | Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer | Molecular Cancer | 2017 | 140 |
| 26 | Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression | Oncotarget | 2017 | 135 |
| 27 | Sintilimab versus placebo in combination with chemotherapy as first line treatment for locally advanced or metastatic oesophageal squamous cell carcinoma (ORIENT-15): multicentre, randomised, double blind, phase 3 trial | BMJ, The | 2022 | 133 |
| 28 | Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression | Cell Death and Disease | 2017 | 131 |
| 29 | Genetic variants in lncRNA HOTAIR are associated with risk of colorectal cancer | Mutagenesis | 2015 | 128 |
| 30 | Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2 | Journal of Hematology and Oncology | 2015 | 122 |
| 31 | c-Myc-induced, long, noncoding H19 affects cell proliferation and predicts a poor prognosis in patients with gastric cancer | Medical Oncology | 2014 | 119 |
| 32 | Superior antitumor efficiency of cisplatin-loaded nanoparticles by intratumoral delivery with decreased tumor metabolism rate | European Journal of Pharmaceutics and Biopharmaceutics | 2008 | 115 |
| 33 | The Pseudogene DUXAP8 Promotes Non-small-cell Lung Cancer Cell Proliferation and Invasion by Epigenetically Silencing EGR1 and RHOB | Molecular Therapy | 2017 | 113 |
| 34 | Downregulated Long Noncoding RNA BANCR Promotes the Proliferation of Colorectal Cancer Cells via Downregualtion of p21 Expression | PLoS ONE | 2015 | 111 |
| 35 | Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer | Journal of Hematology and Oncology | 2017 | 110 |
| 36 | Long intergenic non-coding RNA 00152 promotes lung adenocarcinoma proliferation via interacting with EZH2 and repressing IL24 expression | Molecular Cancer | 2017 | 110 |
| 37 | Self-Assembled Peptide–Lanthanide Nanoclusters for Safe Tumor Therapy: Overcoming and Utilizing Biological Barriers to Peptide Drug Delivery | ACS Nano | 2018 | 110 |
| 38 | Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression | Oncotarget | 2015 | 110 |
| 39 | miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma | PLoS ONE | 2014 | 109 |
| 40 | Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression | Molecular Cancer | 2018 | 109 |
| 41 | Progress and challenges of immunotherapy in triple-negative breast cancer | Biochimica Et Biophysica Acta: Reviews on Cancer | 2021 | 106 |
| 42 | Prognostic value of preoperative NLR, dNLR, PLR and CRP in surgical renal cell carcinoma patients | World Journal of Urology | 2017 | 103 |
| 43 | Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2 | Journal of Hematology and Oncology | 2015 | 103 |
| 44 | Long noncoding RNA SPRY4-IT1 is upregulated in esophageal squamous cell carcinoma and associated with poor prognosis | Tumor Biology | 2014 | 98 |
| 45 | circRNAs and Exosomes: A Mysterious Frontier for Human Cancer | Molecular Therapy - Nucleic Acids | 2020 | 98 |
| 46 | Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancer | EBioMedicine | 2018 | 94 |
| 47 | Long non-coding RNA LINC01133 represses KLF2, P21 and E-cadherin transcription through binding with EZH2, LSD1 in non small cell lung cancer | Oncotarget | 2016 | 92 |
| 48 | Decreased long noncoding RNA SPRY4-IT1 contributing to gastric cancer cell metastasis partly via affecting epithelial–mesenchymal transition | Journal of Translational Medicine | 2015 | 90 |
| 49 | Accurate cancer cell identification and microRNA silencing induced therapy using tailored DNA tetrahedron nanostructures | Chemical Science | 2020 | 90 |
| 50 | Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression | Cell Death and Disease | 2017 | 89 |
