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Top Articles

#TitleJournalYearCitations
1MiR-21 Induced Angiogenesis through AKT and ERK Activation and HIF-1α ExpressionPLoS ONE2011408
2MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesisNucleic Acids Research2012287
3PI3K/PTEN signaling in tumorigenesis and angiogenesisBiochimica Et Biophysica Acta - Proteins and Proteomics2008282
4A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1Journal of Molecular Cell Biology2013242
5Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblastsMolecular Cancer2017216
6Natural Product Interventions for Chemotherapy and Radiotherapy-Induced Side EffectsFrontiers in Pharmacology2018213
7Role of hypoxia-induced exosomes in tumor biologyMolecular Cancer2018211
8Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce AutophagyMolecular Cell2017190
9MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancersCell Cycle2013143
10Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cellsCell Death and Disease2016142
11Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagyAutophagy2015138
12MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1PLoS ONE2012137
13Downregulation of miR-218 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signalingOncogene2017135
14MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in gliomaOncotarget2014125
15Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR‐199a/125b and DNA methylationEMBO Reports2012122
16MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2Journal of Cancer Research and Clinical Oncology2012117
17Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the JAK/STAT signaling activationJournal of Translational Medicine2013113
18Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancerJournal of Experimental and Clinical Cancer Research2014111
19Long intergenic non-coding RNA 00152 promotes lung adenocarcinoma proliferation via interacting with EZH2 and repressing IL24 expressionMolecular Cancer2017110
20Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expressionOncotarget2015110
21Polyploid Giant Cancer Cells (PGCCs): The Evil Roots of CancerCurrent Cancer Drug Targets2019107
22Roles and Mechanism of miR-199a and miR-125b in Tumor AngiogenesisPLoS ONE2013102
23Alteration in Mir-21/PTEN Expression Modulates Gefitinib Resistance in Non-Small Cell Lung CancerPLoS ONE201498
24Chronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1 α /COX-2 PathwayEnvironmental Health Perspectives201496
25KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial BiogenesisMolecular Cell201993
26Regulatory circuit of PKM2/NF-κB/miR-148a/152-modulated tumor angiogenesis and cancer progressionOncogene201590
27Accurate cancer cell identification and microRNA silencing induced therapy using tailored DNA tetrahedron nanostructuresChemical Science202090
28ROR1 expression correlated with poor clinical outcome in human ovarian cancerScientific Reports201488
29Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms201381
30Ganoderma lucidum polysaccharide extract inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation and function by inducing microRNA-125bJournal of Translational Medicine201579
31LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancerOncotarget201679
32Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkersBiochimica Et Biophysica Acta - Proteins and Proteomics200775
33Prognostic significance and potential therapeutic target of VEGFR2 in hepatocellular carcinomaJournal of Clinical Pathology201174
34Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axisCell Death and Disease201874
35Repression of miR-143 Mediates Cr (VI)–Induced Tumor Angiogenesis via IGF-IR/IRS1/ERK/IL-8 PathwayToxicological Sciences201373
36LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancerScientific Reports201671
37Effect of resveratrol on intimal hyperplasia after endothelial denudation in an experimental rabbit modelLife Sciences200070
38Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancerMolecular Cancer201870
39MALAT1-miR-101-SOX9 feedback loop modulates the chemo-resistance of lung cancer cell to DDP via Wnt signaling pathwayOncotarget201769
40New Insight into the Antifibrotic Effects of Praziquantel on Mice in Infection with Schistosoma japonicumPLoS ONE201168
41Different therapeutic effects of cells derived from human amniotic membrane on premature ovarian aging depend on distinct cellular biological characteristicsStem Cell Research and Therapy201768
42Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patientsNature Communications201868
43microRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancerOncology Reports201566
44MiR-148a inhibits angiogenesis by targeting ERBB3Journal of Biomedical Research201165
45Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancersHuman Pathology200863
46AKT2 Regulates Pulmonary Inflammation and Fibrosis via Modulating Macrophage ActivationJournal of Immunology201762
47Inhibition of circular RNA CDR1as increases chemosensitivity of 5‐FU‐resistant BC cells through up‐regulating miR‐7Journal of Cellular and Molecular Medicine201960
48The increase in the expression and hypomethylation of MUC4 gene with the progression of pancreatic ductal adenocarcinomaMedical Oncology201159
49AKT‐dependent phosphorylation of Niban regulates nucleophosmin‐ and MDM2‐mediated p53 stability and cell apoptosisEMBO Reports201259
50Trop2 is overexpressed in gastric cancer and predicts poor prognosisOncotarget201659