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Articles
exaly
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Duke University
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Department of Pharmacology and Cancer Biology
›
Most Cited Articles
Department of Pharmacology and Cancer Biology (most cited articles)
Duke University
830
Articles
50.3K
Citations
6
avg. Impact Factor
109
h-index
Most Cited Articles of Department of Pharmacology and Cancer Biology
Title
Journal
Year
Citations
HDAC6 is a microtubule-associated deacetylase
Nature
2002
2K
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
Cell Metabolism
2008
1.4K
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Cell
2003
1.2K
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
Genes and Development
1999
947
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Nature
2007
932
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
Molecular Cell
2005
898
The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens
Endocrinology
1999
848
A role for ATR in the DNA damage-induced phosphorylation of p53
Genes and Development
1999
779
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
Cell
2015
746
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
Science
2001
665
A novel class of small RNAs in mouse spermatogenic cells
Genes and Development
2006
640
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function
Cell Metabolism
2014
621
Systems biology of vaccination for seasonal influenza in humans
Nature Immunology
2011
589
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
EMBO Journal
2010
584
The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
Nature
1998
532
HDAC6 modulates cell motility by altering the acetylation level of cortactin
Molecular Cell
2007
508
Role of transforming growth factor-beta superfamily signaling pathways in human disease
Biochimica Et Biophysica Acta - Molecular Basis of Disease
2008
473
Interaction of ascorbic acid and mitochondrial lipides
Archives of Biochemistry and Biophysics
1959
459
MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation
EMBO Journal
2002
454
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
EMBO Journal
2001
450
Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype
Journal of Biological Chemistry
2014
444
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
Journal of Cell Biology
2010
420
Molecular biologist's guide to proteomics
Microbiology and Molecular Biology Reviews
2002
383
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
Journal of Biological Chemistry
2005
366
Amiloride: a potent inhibitor of sodium transport across the toad bladder
Journal of Physiology
1968
345
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