| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Protein S-nitrosylation: purview and parameters | Nature Reviews Molecular Cell Biology | 2005 | 1,910 |
| 3 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
| 4 | Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance | Cell Metabolism | 2008 | 1,618 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | Evidence supporting paracrine hypothesis for Akt‐modified mesenchymal stem cell‐mediated cardiac protection and functional improvement | FASEB Journal | 2006 | 1,082 |
| 7 | Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation | Nature Medicine | 1998 | 1,079 |
| 8 | Cardiac Troponin T Levels for Risk Stratification in Acute Myocardial Ischemia | New England Journal of Medicine | 1996 | 1,042 |
| 9 | Mortality, morbidity, and cost associated with febrile neutropenia in adult cancer patients | Cancer | 2006 | 983 |
| 10 | The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function | Cell Metabolism | 2014 | 876 |
| 11 | Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes | PLoS Genetics | 2013 | 844 |
| 12 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 13 | Role of Prostacyclin in the Cardiovascular Response to Thromboxane A2 | Science | 2002 | 775 |
| 14 | The unit of analysis error in studies about physicians’ patient care behavior | Journal of General Internal Medicine | 1992 | 719 |
| 15 | PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease | Science Translational Medicine | 2010 | 691 |
| 16 | (S)NO Signals: Translocation, Regulation, and a Consensus Motif | Neuron | 1997 | 679 |
| 17 | Gait Speed as an Incremental Predictor of Mortality and Major Morbidity in Elderly Patients Undergoing Cardiac Surgery | Journal of the American College of Cardiology | 2010 | 645 |
| 18 | Fractalkine and CX3CR1 Mediate a Novel Mechanism of Leukocyte Capture, Firm Adhesion, and Activation under Physiologic Flow | Journal of Experimental Medicine | 1998 | 641 |
| 19 | American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism | Blood Advances | 2020 | 636 |
| 20 | Amplification of bacterial 16S ribosomal DNA with polymerase chain reaction | Journal of Clinical Microbiology | 1990 | 619 |
| 21 | APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE | Annual Review of Medicine | 1996 | 604 |
| 22 | Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance | Lancet Infectious Diseases, The | 2021 | 586 |
| 23 | A gut-brain neural circuit for nutrient sensory transduction | Science | 2018 | 552 |
| 24 | Hyponatremia Treatment Guidelines 2007: Expert Panel Recommendations | American Journal of Medicine | 2007 | 507 |
| 25 | The global burden of kidney disease and the sustainable development goals | Bulletin of the World Health Organization | 2018 | 504 |
| 26 | Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting | Cell | 1987 | 474 |
| 27 | A Neural Circuit for Gut-Induced Reward | Cell | 2018 | 436 |
| 28 | Visualization of arrestin recruitment by a G-protein-coupled receptor | Nature | 2014 | 433 |
| 29 | National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2 | Journal of Clinical Lipidology | 2015 | 430 |
| 30 | Requirement for Superoxide in Excitotoxic Cell Death | Neuron | 1996 | 426 |
| 31 | Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation | Journal of Biological Chemistry | 2006 | 422 |
| 32 | The effect of hyperoxia on superoxide production by lung submitochondrial particles | Archives of Biochemistry and Biophysics | 1982 | 419 |
| 33 | Importance of the Intracellular Domain of NR2 Subunits for NMDA Receptor Function In Vivo | Cell | 1998 | 419 |
| 34 | Genome‐Wide Association Study Confirms SNPs in SNCA and the MAPT Region as Common Risk Factors for Parkinson Disease | Annals of Human Genetics | 2010 | 417 |
| 35 | Peroxisome Proliferator-activated Receptor-γ Co-activator 1α-mediated Metabolic Remodeling of Skeletal Myocytes Mimics Exercise Training and Reverses Lipid-induced Mitochondrial Inefficiency | Journal of Biological Chemistry | 2005 | 416 |
| 36 | Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans | Cell Host and Microbe | 2009 | 408 |
| 37 | Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants | Nature Medicine | 2007 | 400 |
| 38 | Reliability of the National Institutes of Health Stroke Scale | Stroke | 1997 | 395 |
| 39 | Clinical Characteristics of Patients with Acute Pulmonary Embolism: Data from PIOPED II | American Journal of Medicine | 2007 | 394 |
| 40 | Serum β-2 Microglobulin Levels Predict Mortality in Dialysis Patients: Results of the HEMO Study | Journal of the American Society of Nephrology: JASN | 2006 | 393 |
| 41 | Association of a Peripheral Blood Metabolic Profile With Coronary Artery Disease and Risk of Subsequent Cardiovascular Events | Circulation: Cardiovascular Genetics | 2010 | 390 |
| 42 | A Multiple-Path Model of Particle Deposition in the Rat Lung | Fundamental and Applied Toxicology | 1995 | 388 |
| 43 | The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update | Clinical Pharmacology and Therapeutics | 2014 | 379 |
| 44 | Accuracy of ICD-9-CM Coding for the Identification of Patients With Acute Ischemic Stroke | Stroke | 1998 | 377 |
| 45 | Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial | Lancet, The | 2018 | 374 |
| 46 | Human/Mouse Homology Relationships | Genomics | 1996 | 372 |
| 47 | Interventions for Individuals with Low Health Literacy: A Systematic Review | Journal of Health Communication | 2011 | 369 |
| 48 | The epidemiology of chronic kidney disease in sub-Saharan Africa: a systematic review and meta-analysis | The Lancet Global Health | 2014 | 368 |
| 49 | Hyperoxia increases H2O2 release by lung mitochondria and microsomes | Archives of Biochemistry and Biophysics | 1982 | 365 |
| 50 | A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1 | Nature | 2011 | 360 |
