| # | Title | Journal | Year | Citations |
|---|
| 1 | Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis | Gastroenterology | 2004 | 162 |
| 2 | Pirfenidone effectively reverses experimental liver fibrosis | Journal of Hepatology | 2002 | 140 |
| 3 | Potent antioxidant role of Pirfenidone in experimental cirrhosis | European Journal of Pharmacology | 2008 | 82 |
| 4 | Pathophysiological Molecular Mechanisms of Obesity: A Link between MAFLD and NASH with Cardiovascular Diseases | International Journal of Molecular Sciences | 2021 | 73 |
| 5 | A pilot study in patients with established advanced liver fibrosis using pirfenidone | Gut | 2006 | 68 |
| 6 | Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge | Cells | 2021 | 55 |
| 7 | A Controlled Clinical Trial With Pirfenidone in the Treatment of Pathological Skin Scarring Caused by Burns in Pediatric Patients | Annals of Plastic Surgery | 2012 | 44 |
| 8 | Molecular Basis and Current Treatment for Alcoholic Liver Disease | International Journal of Environmental Research and Public Health | 2010 | 34 |
| 9 | Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK | Hepatology Communications | 2020 | 33 |
| 10 | Molecular diagnosis of Chagas' disease and use of an animal model to study parasite tropism | Parasitology Research | 2003 | 32 |
| 11 | Delphinidin Ameliorates Hepatic Triglyceride Accumulation in Human HepG2 Cells, but Not in Diet-Induced Obese Mice | Nutrients | 2018 | 32 |
| 12 | Renal dysfunction as a consequence of acute liver damage by bile duct ligation in cirrhotic rats | Experimental and Toxicologic Pathology | 2006 | 31 |
| 13 | Pirfenidone restricts Th2 differentiation in vitro and limits Th2 response in experimental liver fibrosis | European Journal of Pharmacology | 2012 | 25 |
| 14 | Adenoviral delivery of dominant‐negative transforming growth factor β type II receptor up‐regulates transcriptional repressor SKI‐like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats | Journal of Gene Medicine | 2009 | 22 |
| 15 | Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenine | PLoS ONE | 2017 | 21 |
| 16 | Epidemiologic, Genetic, Pathogenic, Metabolic, Epigenetic Aspects Involved in NASH-HCC: Current Therapeutic Strategies | Cancers | 2023 | 21 |
| 17 | Increased DNA binding activity of NF-kB, STAT-3, SMAD3 and AP-1 in acutely damaged liver | World Journal of Gastroenterology | 2006 | 18 |
| 18 | Urokinase plasminogen activator stimulates function of active forms of stromelysin and gelatinases (MMP-2 and MMP-9) in cirrhotic tissue | Journal of Gastroenterology and Hepatology (Australia) | 2006 | 16 |
| 19 | Capsaicin induces a protective effect on gastric mucosa along with decreased expression of inflammatory molecules in a gastritis model | Journal of Functional Foods | 2019 | 16 |
| 20 | Prolonged-release pirfenidone prevents obesity-induced cardiac steatosis and fibrosis in a mouse NASH model | Cardiovascular Drugs and Therapy | 2021 | 16 |
| 21 | Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH | Scientific Reports | 2021 | 12 |
| 22 | An Update in Epigenetics in Metabolic-Associated Fatty Liver Disease | Frontiers in Medicine | 2021 | 12 |
| 23 | Amplified expression of dominant-negative transforming growth factor-beta type II receptor inhibits collagen type I production via reduced Smad-3 activity | Journal of Gastroenterology and Hepatology (Australia) | 2004 | 9 |
| 24 | Adenoviral gene therapy in hepatocellular carcinoma: a review | Hepatology International | 2013 | 8 |
| 25 | Moringa oleifera Improves MAFLD by Inducing Epigenetic Modifications | Nutrients | 2022 | 8 |
| 26 | Plasmin plays a key role in the regulation of profibrogenic molecules in hepatic stellate cells | Liver International | 2010 | 6 |
| 27 | Combinatorial gene therapy renders increased survival in cirrhotic rats | Journal of Biomedical Science | 2010 | 5 |
| 28 | Human adipose derived stem cells reduce fibrosis in an experimental model of chronic kidney damage | Cytotherapy | 2017 | 2 |
| 29 | Fibrosis regression is induced by AdhMMP8 in a murine model of chronic kidney injury | PLoS ONE | 2020 | 2 |
| 30 | Dietary supplementation with Mexican foods, Opuntia ficus indica, Theobroma cacao, and Acheta domesticus: Improving obesogenic and microbiota features in obese mice | Frontiers in Nutrition | 0 | 2 |
| 31 | Mexican Ancestral Foods (Theobroma cacao, Opuntia ficus indica, Persea americana and Phaseolus vulgaris) Supplementation on Anthropometric, Lipid and Glycemic Control Variables in Obese Patients: A Systematic Review and Meta-Analysis | Foods | 2023 | 2 |
| 32 | Prolonged-release pirfenidone prevents myocardial fibrosis in a mouse nonalcoholic steatohepatitis model | Annals of Hepatology | 2020 | 0 |
