| # | Title | Journal | Year | Citations |
|---|
| 1 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 2 | Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine | 2019 | 4,108 |
| 3 | The effect of human mobility and control measures on the COVID-19 epidemic in China | Science | 2020 | 2,168 |
| 4 | Quality of Life and Satisfaction with Outcome among Prostate-Cancer Survivors | New England Journal of Medicine | 2008 | 2,030 |
| 5 | Adverse metabolic and cardiovascular consequences of circadian misalignment | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 1,770 |
| 6 | Impacts of biodiversity on the emergence and transmission of infectious diseases | Nature | 2010 | 1,481 |
| 7 | Neuronal subtype specification in the cerebral cortex | Nature Reviews Neuroscience | 2007 | 1,444 |
| 8 | Assembly-Line Enzymology for Polyketide and Nonribosomal Peptide Antibiotics: Logic, Machinery, and Mechanisms | Chemical Reviews | 2006 | 1,278 |
| 9 | A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure | Cell Systems | 2016 | 1,098 |
| 10 | Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure | New England Journal of Medicine | 2021 | 1,080 |
| 11 | Expanding global access to radiotherapy | Lancet Oncology, The | 2015 | 709 |
| 12 | Past and future spread of the arbovirus vectors Aedes aegypti and Aedes albopictus | Nature Microbiology | 2019 | 699 |
| 13 | The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future | Lancet, The | 2021 | 669 |
| 14 | Evolutionary paths to antibiotic resistance under dynamically sustained drug selection | Nature Genetics | 2012 | 651 |
| 15 | Toehold Switches: De-Novo-Designed Regulators of Gene Expression | Cell | 2014 | 646 |
| 16 | The current and future global distribution and population at risk of dengue | Nature Microbiology | 2019 | 645 |
| 17 | Sustainable data analysis with Snakemake | F1000Research | 2021 | 642 |
| 18 | Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL | Nature Cell Biology | 2001 | 536 |
| 19 | The global economic burden of diabetes in adults aged 20–79 years: a cost-of-illness study | Lancet Diabetes and Endocrinology,the | 2017 | 511 |
| 20 | Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism | Obesity | 2009 | 501 |
| 21 | Relationship between body image disturbance and incidence of depression: the SUN prospective cohort | BMC Public Health | 2009 | 494 |
| 22 | A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection | Science | 2010 | 457 |
| 23 | Engineering cyanobacteria to generate high-value products | Trends in Biotechnology | 2011 | 443 |
| 24 | Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels | Science | 2012 | 428 |
| 25 | The National Sleep Research Resource: towards a sleep data commons | Journal of the American Medical Informatics Association: JAMIA | 2018 | 418 |
| 26 | Poverty, depression, and anxiety: Causal evidence and mechanisms | Science | 2020 | 417 |
| 27 | The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels | Lancet, The | 2022 | 402 |
| 28 | Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis | Molecular Cell | 2008 | 389 |
| 29 | Internally Generated Preactivation of Single Neurons in Human Medial Frontal Cortex Predicts Volition | Neuron | 2011 | 383 |
| 30 | Institutional trust and misinformation in the response to the 2018–19 Ebola outbreak in North Kivu, DR Congo: a population-based survey | Lancet Infectious Diseases, The | 2019 | 382 |
| 31 | An open-source drug discovery platform enables ultra-large virtual screens | Nature | 2020 | 345 |
| 32 | Hip replacement | Lancet, The | 2018 | 341 |
| 33 | Single-Molecule Kinetics of Exonuclease Reveal Base Dependence and Dynamic Disorder | Science | 2003 | 335 |
| 34 | Quantitative super-resolution imaging with qPAINT | Nature Methods | 2016 | 328 |
| 35 | Diabetes in sub-Saharan Africa: from clinical care to health policy | Lancet Diabetes and Endocrinology,the | 2017 | 328 |
| 36 | Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine | Science | 2007 | 327 |
| 37 | Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 322 |
| 38 | Complex cellular logic computation using ribocomputing devices | Nature | 2017 | 321 |
| 39 | Low-Frequency HIV-1 Drug Resistance Mutations and Risk of NNRTI-Based Antiretroviral Treatment Failure | JAMA - Journal of the American Medical Association | 2011 | 315 |
| 40 | THE EVOLUTION OF AGRICULTURE IN BEETLES (CURCULIONIDAE: SCOLYTINAE AND PLATYPODINAE) | Evolution; International Journal of Organic Evolution | 2001 | 308 |
| 41 | Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-PAINT | Science | 2014 | 299 |
| 42 | Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19 | JAMA - Journal of the American Medical Association | 2021 | 299 |
| 43 | Fractional Fourier transform as a signal processing tool: An overview of recent developments | Signal Processing | 2011 | 298 |
| 44 | Rerouting Carbon Flux To Enhance Photosynthetic Productivity | Applied and Environmental Microbiology | 2012 | 298 |
| 45 | Kynurenine Pathway Measurements in Huntington's Disease Striatum: Evidence for Reduced Formation of Kynurenic Acid | Journal of Neurochemistry | 1990 | 297 |
| 46 | Association of “Weekend Warrior” and Other Leisure Time Physical Activity Patterns With Risks for All-Cause, Cardiovascular Disease, and Cancer Mortality | JAMA Internal Medicine | 2017 | 294 |
| 47 | β-Barrel Membrane Protein Assembly by the Bam Complex | Annual Review of Biochemistry | 2011 | 290 |
| 48 | The Harvard Automated Processing Pipeline for Electroencephalography (HAPPE): Standardized Processing Software for Developmental and High-Artifact Data | Frontiers in Neuroscience | 2018 | 290 |
| 49 | The prevalence of suicidal thoughts and behaviours among college students: a meta-analysis | Psychological Medicine | 2018 | 285 |
| 50 | B Lymphocytes and Cancer: A Love–Hate Relationship | Trends in Cancer | 2016 | 284 |
