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Top Articles

#TitleJournalYearCitations
1Gut Microbiome and Metabolome Profiles Associated with High-Fat Diet in MiceMetabolites202150
2Integration of MicroRNA, mRNA, and Protein Expression Data for the Identification of Cancer-Related MicroRNAsPLoS ONE201740
3Potential Therapeutic Applications of Bee Venom on Skin Disease and Its Mechanisms: A Literature ReviewToxins201937
4Guggulsterone attenuates cerulein-induced acute pancreatitis via inhibition of ERK and JNK activationInternational Immunopharmacology201533
5Intensive management program to improve glycosylated hemoglobin levels and adherence to diet in patients with type 2 diabetesApplied Nursing Research200927
6Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemiaOncotarget201626
7HerDing: herb recommendation system to treat diseases using genes and chemicalsDatabase: the Journal of Biological Databases and Curation201626
8Laser Acupuncture Exerts Neuroprotective Effects via Regulation ofCreb,Bdnf,Bcl-2, andBaxGene Expressions in the HippocampusEvidence-based Complementary and Alternative Medicine201726
9Inhibitory Effect of Sestrin 2 on Hepatic Stellate Cell Activation and Liver FibrosisAntioxidants and Redox Signaling201926
10The 3-deoxysappanchalcone induces ROS-mediated apoptosis and cell cycle arrest via JNK/p38 MAPKs signaling pathway in human esophageal cancer cellsPhytomedicine202126
11Anti-inflammatory effect of desoxo-narchinol-A isolated from Nardostachys jatamansi against lipopolysaccharideInternational Immunopharmacology201524
12The prognostic impact of mutations in spliceosomal genes for myelodysplastic syndrome patients without ring sideroblastsBMC Cancer201524
13Longitudinal associations between glucocorticoid receptor methylation and late-life depressionProgress in Neuro-Psychopharmacology and Biological Psychiatry201824
14Evaluation of Anti-Inflammatory Potential of the New Ganghwaljetongyeum on Adjuvant-Induced Inflammatory Arthritis in RatsEvidence-based Complementary and Alternative Medicine201621
15Dasatinib Inhibits Lung Cancer Cell Growth and Patient Derived Tumor Growth in Mice by Targeting LIMK1Frontiers in Cell and Developmental Biology202021
16Astrocyte D-serine modulates the activation of neuronal NOS leading to the development of mechanical allodynia in peripheral neuropathyMolecular Pain201920
17Chondroprotective and anti-inflammatory effects of ChondroT, a new complex herbal medicationBMC Complementary and Alternative Medicine201619
18Anti-osteoarthritic effects of ChondroT in a rat model of collagenase-induced osteoarthritisBMC Complementary and Alternative Medicine201819
19Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growthPhytotherapy Research202018
20Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivoJournal of Experimental and Clinical Cancer Research202118
21PBK/TOPK: An Effective Drug Target with Diverse Therapeutic PotentialCancers202118
22REDD1 attenuates hepatic stellate cell activation and liver fibrosis via inhibiting of TGF-β/Smad signaling pathwayFree Radical Biology and Medicine202118
23Alternative Options for Skin Cancer Therapy via Regulation of AKT and Related Signaling PathwaysInternational Journal of Molecular Sciences202017
24Neuroprotective Activity of Melittin—The Main Component of Bee Venom—Against Oxidative Stress Induced by Aβ25–35 in In Vitro and In Vivo ModelsAntioxidants202117
25Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cellsPhytomedicine202116
26A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma ImmunotherapyFrontiers in Immunology202116
27Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial FunctionAnnals of Laboratory Medicine201815
28Spinal cytochrome P450c17 plays a key role in the development of neuropathic mechanical allodynia: Involvement of astrocyte sigma-1 receptorsNeuropharmacology201915
29Long-Term Exposure to Urban Particulate Matter on the Ocular Surface and the Incidence of Deleterious Changes in the Cornea, Conjunctiva and Retina in RatsInternational Journal of Molecular Sciences202015
30Medication Trends for Age-Related Macular DegenerationInternational Journal of Molecular Sciences202115
31Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implicationsBMC Cancer201514
32Effects of ChondroT on potassium Oxonate-induced Hyperuricemic mice: downregulation of xanthine oxidase and urate transporter 1BMC Complementary and Alternative Medicine201914
33Bamboo Stems (Phyllostachys nigra variety henosis) Containing Polyphenol Mixtures Activate Nrf2 and Attenuate Phenylhydrazine-Induced Oxidative Stress and Liver InjuryNutrients201914
34Echinatin induces reactive oxygen species‐mediated apoptosis via JNK/p38 MAPK signaling pathway in colorectal cancer cellsPhytotherapy Research202314
35Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivoFrontiers in Cell and Developmental Biology202013
36Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK PathwaysInternational Journal of Molecular Sciences202013
37Unripe Rubus coreanus Miquel Extract Containing Ellagic Acid Promotes Lipolysis and Thermogenesis In Vitro and In VivoMolecules202012
38Antiosteoarthritic Effects of ChondroT in a Rat Model of Monosodium Iodoacetate-Induced OsteoarthritisEvidence-based Complementary and Alternative Medicine201811
39Cognitive Improvement Effects of Electroacupuncture Combined with Computer-Based Cognitive Rehabilitation in Patients with Mild Cognitive Impairment: A Randomized Controlled TrialBrain Sciences202011
40Spectrum of mitochondrial genome instability and implication of mitochondrial haplogroups in Korean patients with acute myeloid leukemiaBlood Research201810
41Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGE2 pathwaysJournal of Ginseng Research202010
42Factors contributing to cognitive improvement effects of acupuncture in patients with mild cognitive impairment: a pilot randomized controlled trialTrials202110
43Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK SignalingBiomolecules and Therapeutics202110
44Bee Venom Activates the Nrf2/HO-1 and TrkB/CREB/BDNF Pathways in Neuronal Cell Responses against Oxidative Stress Induced by Aβ1–42International Journal of Molecular Sciences202210
45Ferroptosis contribute to hepatic stellate cell activation and liver fibrogenesisFree Radical Biology and Medicine202210
46A longitudinal study of the associations of BDNF genotype and methylation with poststroke anxietyInternational Journal of Geriatric Psychiatry20199
47Neoagarooligosaccharide Protects against Hepatic Fibrosis via Inhibition of TGF-β/Smad Signaling PathwayInternational Journal of Molecular Sciences20219
48Animal Venom for Medical Usage in Pharmacopuncture in Korean Medicine: Current Status and Clinical ImplicationToxins20219
49Deoxypodophyllotoxin Inhibits Cell Growth and Induces Apoptosis by Blocking EGFR and MET in Gefitinib-Resistant Non-Small Cell Lung CancerJournal of Microbiology and Biotechnology20219
50Effects of different acupuncture treatment methods on mild cognitive impairment: a study protocol for a randomized controlled trialTrials20198