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Top Articles

#TitleJournalYearCitations
1Ferroptosis and Its Role in Diverse Brain DiseasesMolecular Neurobiology2019319
2ATP-Dependent Dynamic Protein Aggregation Regulates Bacterial Dormancy Depth Critical for Antibiotic ToleranceMolecular Cell2019221
3Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxiaNature Communications2019140
4Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathwayCarcinogenesis2012137
5Proteomic Analysis of β1-Adrenergic Receptor Interactions with PDZ Scaffold ProteinsJournal of Biological Chemistry2006105
6Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cellsCell Death and Disease201396
7Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesisJournal of Clinical Investigation201884
8MicroRNA miR-886-5p inhibits apoptosis by down-regulating Bax expression in human cervical carcinoma cellsGynecologic Oncology201180
9Whole‐genome microRNA expression profiling identifies a 5‐microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiformeCancer201379
10mRNAsi Index: Machine Learning in Mining Lung Adenocarcinoma Stem Cell BiomarkersGenes202079
11Adeno-associated virus 2 bound to its cellular receptor AAVRNature Microbiology201976
12Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination–mediated DNA repairScience Advances202073
13Hsp70 promotes chemoresistance by blocking Bax mitochondrial translocation in ovarian cancer cellsCancer Letters201269
14Human osteopontin: Potential clinical applications in cancer (Review)International Journal of Molecular Medicine201769
15PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5–WDR77/CRL4B complex to promote tumorigenesisNucleic Acids Research201868
16SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesisFree Radical Biology and Medicine201965
17Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesisCell Research201857
18LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancerJournal of Molecular Cell Biology201854
19Proteomic analysis of the OGT interactome: novel links to epithelial–mesenchymal transition and metastasis of cervical cancerCarcinogenesis201853
20Effect of microRNA‐210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemiaCancer Science201452
21MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinomaScientific Reports201752
22Divergent engagements between adeno-associated viruses with their cellular receptor AAVRNature Communications201952
23The Tyrosine Kinase c-Src Directly Mediates Growth Factor-Induced Notch-1 and Furin Interaction and Notch-1 Activation in Pancreatic Cancer CellsPLoS ONE201251
24Identification of key modules and genes associated with breast cancer prognosis using WGCNA and ceRNA network analysisAging202151
25Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancerCancer Letters201942
26Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesisProceedings of the National Academy of Sciences of the United States of America201840
27Risk of Immune-Related Pancreatitis in Patients with Solid Tumors Treated with Immune Checkpoint Inhibitors: Systematic Assessment with Meta-AnalysisJournal of Immunology Research201840
28Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibitionCell Death and Differentiation202140
29Simultaneous 3-Nitrophenylhydrazine Derivatization Strategy of Carbonyl, Carboxyl and Phosphoryl Submetabolome for LC-MS/MS-Based Targeted Metabolomics with Improved Sensitivity and CoverageAnalytical Chemistry202140
30Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammationProceedings of the National Academy of Sciences of the United States of America201439
31NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer CellsInternational Journal of Molecular Sciences201739
32Sulforaphane Induced Apoptosis via Promotion of Mitochondrial Fusion and ERK1/2-Mediated 26S Proteasome Degradation of Novel Pro-survival Bim and Upregulation of Bax in Human Non-Small Cell Lung Cancer CellsJournal of Cancer201739
33Na(+)/H(+) Exchanger Regulatory Factor 1 (NHERF1) Is Required for the Estradiol-Dependent Increase of Phosphatase and Tensin Homolog (PTEN) Protein ExpressionEndocrinology201138
34Sulforaphane Inhibits Invasion via Activating ERK1/2 Signaling in Human Glioblastoma U87MG and U373MG CellsPLoS ONE201438
35A review of Omics research in acupuncture: The relevance and future prospects for understanding the nature of meridians and acupointsJournal of Ethnopharmacology201237
36Ang-(1-7) promotes the migration and invasion of human renal cell carcinoma cells via Mas-mediated AKT signaling pathwayBiochemical and Biophysical Research Communications201537
37Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growthJournal of Experimental Medicine202037
38Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173Molecular and Cellular Biochemistry201136
39Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cellsOncology Reports201535
40Depending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM‐induced autophagy or BAXLiver International201334
41Decorin‐mediated inhibition of the migration of U87MG glioma cells involves activation of autophagy and suppression of TGF‐β signalingFEBS Open Bio201634
42The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked DeubiquitinationJournal of Immunology201934
43The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitrySignal Transduction and Targeted Therapy202134
44EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylationAmino Acids201233
45Traditional Chinese medicine <em>Astragalus </em>polysaccharide enhanced antitumor effects of the angiogenesis inhibitor apatinib in pancreatic cancer cells on proliferation, invasiveness, and apoptosisOncoTargets and Therapy201833
46ISL1 predicts poor outcomes for patients with gastric cancer and drives tumor progression through binding to the ZEB1 promoter together with SETD7Cell Death and Disease201932
47USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesisCellular Signalling201932
48NDUFA4L2 is associated with clear cell renal cell carcinoma malignancy and is regulated by ELK1PeerJ201732
49HDAC4 stabilizes SIRT1 via sumoylation SIRT1 to delay cellular senescenceClinical and Experimental Pharmacology and Physiology201631
50miR-19a correlates with poor prognosis of clear cell renal cell carcinoma patients via promoting cell proliferation and suppressing PTEN/SMAD4 expressionInternational Journal of Oncology201631