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#TitleJournalYearCitations
1Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical BiologyJournal of Medicinal Chemistry20131,002
2In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancerNature Medicine2014242
3Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53Journal of the American Chemical Society2012202
4Evaluation and Optimization of Virtual Screening Workflows with DEKOIS 2.0 – A Public Library of Challenging Docking Benchmark SetsJournal of Chemical Information and Modeling2013134
5Flavonoids Inhibit COX-1 and COX-2 Enzymes and Cytokine/Chemokine Production in Human Whole BloodInflammation201592
6Inhibitors of c-Jun N-Terminal Kinases: An UpdateJournal of Medicinal Chemistry201581
7Inhibition of GSK3 differentially modulates NF-κB, CREB, AP-1 and β-catenin signaling in hepatocytes, but fails to promote TNF-α-induced apoptosisExperimental Cell Research200869
8DEKOIS: Demanding Evaluation Kits for Objective in Silico Screening — A Versatile Tool for Benchmarking Docking Programs and Scoring FunctionsJournal of Chemical Information and Modeling201168
9Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of actionPhytochemistry201260
10Tetra-Substituted Pyridinylimidazoles As Dual Inhibitors of p38α Mitogen-Activated Protein Kinase and c-Jun N-Terminal Kinase 3 for Potential Treatment of Neurodegenerative DiseasesJournal of Medicinal Chemistry201543
11Design, Synthesis, and Biological Evaluation of Phenylamino-Substituted 6,11-Dihydro-dibenzo[b,e]oxepin-11-ones and Dibenzo[a,d]cycloheptan-5-ones:  Novel p38 MAP Kinase InhibitorsJournal of Medicinal Chemistry200640
12Are MAP Kinases Drug Targets? Yes, but Difficult OnesChemMedChem200740
13Optimization of a nonradioactive immunosorbent assay for p38α mitogen-activated protein kinase activityAnalytical Biochemistry201037
14Tri- and tetrasubstituted imidazoles as p38α mitogen-activated protein kinase inhibitorsBioorganic and Medicinal Chemistry Letters201036
15Biological Evaluation and Structural Determinants of p38α Mitogen‐Activated‐Protein Kinase and c‐Jun‐N‐Terminal Kinase 3 Inhibition by FlavonoidsChemBioChem201034
16Isoxazolone Based Inhibitors of p38 MAP KinasesJournal of Medicinal Chemistry200832
17Substituted Isoxazoles as Potent Inhibitors of p38 MAP KinaseChemMedChem200631
18Novel Hinge‐Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure–Activity Relationship Study on Tofacitinib BioisosteresChemMedChem201428
19Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitorsEuropean Journal of Medicinal Chemistry201926
20Aza-Analogue Dibenzepinone Scaffolds as p38 Mitogen-Activated Protein Kinase Inhibitors: Design, Synthesis, and Biological Data of Inhibitors with Improved Physicochemical PropertiesJournal of Medicinal Chemistry200925
21Antinociceptive, anti-inflammatory and gastroprotective effects of a hydroalcoholic extract from the leaves of Eugenia punicifolia (Kunth) DC. in rodentsJournal of Ethnopharmacology201424
22Impact of p38 MAP Kinase Inhibitors on LPS-Induced Release of TNF-α in Whole Blood and Primary Cells from Different SpeciesCellular Physiology and Biochemistry201524
23Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-SpineJournal of Medicinal Chemistry201724
24Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3ACS Omega201824
25Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen BioisostereACS Chemical Biology201523
26Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1Clinical Pharmacology and Therapeutics202023
27A Highly Selective In Vitro JNK3 Inhibitor, FMU200, Restores Mitochondrial Membrane Potential and Reduces Oxidative Stress and Apoptosis in SH-SY5Y CellsInternational Journal of Molecular Sciences202122
28A direct ELISA assay for quantitative determination of the inhibitory potency of small molecules inhibitors for JNK3Journal of Pharmaceutical and Biomedical Analysis201121
29Discovery of Novel Orally Active Anti-Inflammatory N-Phenylpyrazolyl-N-Glycinyl-Hydrazone Derivatives That Inhibit TNF-α ProductionPLoS ONE201221
30Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasisEuropean Journal of Pharmacology201221
31pROC-Chemotype Plots Enhance the Interpretability of Benchmarking Results in Structure-Based Virtual ScreeningJournal of Chemical Information and Modeling201520
32Antimicrobial and antileukemic effects: in vitro activity of Calyptranthes grandifolia aqueous leaf extractJournal of Toxicology and Environmental Health - Part A: Current Issues202020
33SCISSOR—Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocolBMJ Open201617
34SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditionsScientific Reports202117
35Decisive role of water and protein dynamics in residence time of p38α MAP kinase inhibitorsNature Communications202217
36Synthesis and Biological Testing of N‐Aminoimidazole‐Based p38α MAP Kinase InhibitorsChemMedChem201016
37Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactionsTheranostics201916
38Neuroprotective Effect of Luteolin-7-O-Glucoside against 6-OHDA-Induced Damage in Undifferentiated and RA-Differentiated SH-SY5Y CellsInternational Journal of Molecular Sciences202216
39Unexpected Reaction of 2-Alkylsulfanylimidazoles to Imidazol-2-ones: Pyridinylimidazol-2-ones as Novel Potent p38α Mitogen-Activated Protein Kinase InhibitorsJournal of Medicinal Chemistry201015
40A direct enzyme-linked immunosorbent assay (ELISA) for the quantitative evaluation of Janus Kinase 3 (JAK3) inhibitorsAnalytical Methods201415
41Targeting the protein backbone with aryl halides: systematic comparison of halogen bonding and π⋯π interactions using N-methylacetamideMedChemComm201614
42Myricetin inhibits panel of kinases implicated in tumorigenesisBasic and Clinical Pharmacology and Toxicology201914
43ACKR3 regulates platelet activation and ischemia-reperfusion tissue injuryNature Communications202213
44Neuromodulatory effects of Calyptranthes grandifolia extracts against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cellsBiomedicine and Pharmacotherapy201612
45Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water NetworksACS Medicinal Chemistry Letters201912
46Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448)ACS Medicinal Chemistry Letters202211
47From 2-Alkylsulfanylimidazoles to 2-Alkylimidazoles: An Approach towards Metabolically More Stable p38α MAP Kinase InhibitorsMolecules201710
48Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the dual p38/JNK 3 inhibitor LN 950 in experimental K/BxN serum transfer arthritisInflammopharmacology201910
49A Special View of What Was Almost Forgotten: p38δ MAPKCancers202110
50Current jakinibs for the treatment of rheumatoid arthritis: a systematic reviewInflammopharmacology202110