# | Title | Journal | Year | Citations |
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1 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine | Analytical Biochemistry | 1980 | 4,155 |
2 | Endocytic recycling | Nature Reviews Molecular Cell Biology | 2004 | 1,657 |
3 | Endocytosis | Physiological Reviews | 1997 | 1,362 |
4 | Glutathione metabolism and its selective modification | Journal of Biological Chemistry | 1988 | 1,242 |
5 | Role of cholesterol and lipid organization in disease | Nature | 2005 | 1,102 |
6 | The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis | Cell | 2012 | 968 |
7 | Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling | Nature | 2010 | 911 |
8 | An essential role for free radicals and derived species in signal transduction | FASEB Journal | 1997 | 844 |
9 | Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy | | 1991 | 825 |
10 | Molecular Basis of NF-κB Signaling | Annual Review of Biophysics | 2013 | 769 |
11 | Energetics of ion conduction through the K+ channel | Nature | 2001 | 745 |
12 | Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress | Journal of Biological Chemistry | 1997 | 713 |
13 | Lipid landscapes and pipelines in membrane homeostasis | Nature | 2014 | 697 |
14 | A method for efficient isotopic labeling of recombinant proteins | Journal of Biomolecular NMR | 2001 | 676 |
15 | Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects | Cell | 2014 | 639 |
16 | A simple polarizable model of water based on classical Drude oscillators | Journal of Chemical Physics | 2003 | 635 |
17 | Distinct molecular mechanism for initiating TRAF6 signalling | Nature | 2002 | 608 |
18 | Activity-Driven Local ATP Synthesis Is Required for Synaptic Function | Cell | 2014 | 598 |
19 | Modeling induced polarization with classical Drude oscillators: Theory and molecular dynamics simulation algorithm | Journal of Chemical Physics | 2003 | 584 |
20 | A polarizable model of water for molecular dynamics simulations of biomolecules | Chemical Physics Letters | 2006 | 548 |
21 | Glutathione-ascorbic acid antioxidant system in animals | Journal of Biological Chemistry | 1994 | 518 |
22 | All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction | Journal of Cell Science | 2002 | 514 |
23 | AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1 | Molecular Cell | 2013 | 508 |
24 | Interaction of γ-Glutamyl Transpeptidase with Amino Acids, Dipeptides, and Derivatives and Analogs of Glutathione | Journal of Biological Chemistry | 1974 | 506 |
25 | A Selective Activity-Dependent Requirement for Dynamin 1 in Synaptic Vesicle Endocytosis | Science | 2007 | 454 |
26 | NG-methylarginine, and inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: Does nitric oxide regulate blood pressure in vivo? | Biochemical and Biophysical Research Communications | 1989 | 444 |
27 | All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction | Journal of Cell Science | 2002 | 440 |
28 | γ-Glutamyl transpeptidase: catalytic, structural and functional aspects | Molecular and Cellular Biochemistry | 1981 | 435 |
29 | A Molecular Redox Switch on p21 | Journal of Biological Chemistry | 1997 | 433 |
30 | Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1 | Journal of Virology | 2002 | 424 |
31 | The Akt kinases: Isoform specificity in metabolism and cancer | Cell Cycle | 2009 | 424 |
32 | Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons | Brain Research | 1989 | 411 |
33 | Vitamin E, Ascorbate, Glutathione, Glutathicne Disulfide, and Enzymes of Glutathione Metabolism in Cultures of Chick Astrocytes and Neurons: Evidence that Astrocytes Play an Important Role in Antioxidative Processes in the Brain | Journal of Neurochemistry | 1994 | 388 |
34 | Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system | Nature Cell Biology | 2000 | 386 |
35 | MEMBRANE DOMAINS | Annual Review of Cell and Developmental Biology | 2004 | 381 |
36 | Metabolic Enzymes of Mycobacteria Linked to Antioxidant Defense by a Thioredoxin-Like Protein | Science | 2002 | 378 |
37 | Glutathione, a first line of defense against cadmium toxicity | FASEB Journal | 1987 | 372 |
38 | [1] Glutathione metabolism | Methods in Enzymology | 1995 | 372 |
39 | Dynamic Coupling between the SH2 and SH3 Domains of c-Src and Hck Underlies Their Inactivation by C-Terminal Tyrosine Phosphorylation | Cell | 2001 | 366 |
40 | Theoretical and computational models of biological ion channels | Quarterly Reviews of Biophysics | 2004 | 362 |
41 | Endocytic Sorting of Lipid Analogues Differing Solely in the Chemistry of Their Hydrophobic Tails | Journal of Cell Biology | 1999 | 359 |
42 | Ion Permeation and Selectivity of OmpF Porin: A Theoretical Study Based on Molecular Dynamics, Brownian Dynamics, and Continuum Electrodiffusion Theory | Journal of Molecular Biology | 2002 | 353 |
43 | Acquisition of siderophores in Gram-negative bacteria | Nature Reviews Molecular Cell Biology | 2003 | 349 |
44 | Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens. | Proceedings of the National Academy of Sciences of the United States of America | 1990 | 348 |
45 | p21 as a Common Signaling Target of Reactive Free Radicals and Cellular Redox Stress | Journal of Biological Chemistry | 1995 | 347 |
46 | Glutathione monoethyl ester: Preparation, uptake by tissues, and conversion to glutathione | Archives of Biochemistry and Biophysics | 1985 | 344 |
47 | On the antioxidant effects of ascorbic acid and glutathione | Biochemical Pharmacology | 1992 | 342 |
48 | Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking | Nature | 2004 | 341 |
49 | Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation | Journal of Biological Chemistry | 2007 | 321 |
50 | Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies | Oncogene | 2015 | 321 |