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Top Articles

#TitleJournalYearCitations
1Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridineAnalytical Biochemistry19804,155
2Endocytic recyclingNature Reviews Molecular Cell Biology20041,657
3EndocytosisPhysiological Reviews19971,362
4Glutathione metabolism and its selective modificationJournal of Biological Chemistry19881,242
5Role of cholesterol and lipid organization in diseaseNature20051,102
6The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed NecrosisCell2012968
7Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signallingNature2010911
8An essential role for free radicals and derived species in signal transductionFASEB Journal1997844
9Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy1991825
10Molecular Basis of NF-κB SignalingAnnual Review of Biophysics2013769
11Energetics of ion conduction through the K+ channelNature2001745
12Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant StressJournal of Biological Chemistry1997713
13Lipid landscapes and pipelines in membrane homeostasisNature2014697
14A method for efficient isotopic labeling of recombinant proteinsJournal of Biomolecular NMR2001676
15Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory EffectsCell2014639
16A simple polarizable model of water based on classical Drude oscillatorsJournal of Chemical Physics2003635
17Distinct molecular mechanism for initiating TRAF6 signallingNature2002608
18Activity-Driven Local ATP Synthesis Is Required for Synaptic FunctionCell2014598
19Modeling induced polarization with classical Drude oscillators: Theory and molecular dynamics simulation algorithmJournal of Chemical Physics2003584
20A polarizable model of water for molecular dynamics simulations of biomoleculesChemical Physics Letters2006548
21Glutathione-ascorbic acid antioxidant system in animalsJournal of Biological Chemistry1994518
22All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transductionJournal of Cell Science2002514
23AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1Molecular Cell2013508
24Interaction of γ-Glutamyl Transpeptidase with Amino Acids, Dipeptides, and Derivatives and Analogs of GlutathioneJournal of Biological Chemistry1974506
25A Selective Activity-Dependent Requirement for Dynamin 1 in Synaptic Vesicle EndocytosisScience2007454
26NG-methylarginine, and inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: Does nitric oxide regulate blood pressure in vivo?Biochemical and Biophysical Research Communications1989444
27All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transductionJournal of Cell Science2002440
28γ-Glutamyl transpeptidase: catalytic, structural and functional aspectsMolecular and Cellular Biochemistry1981435
29A Molecular Redox Switch on p21Journal of Biological Chemistry1997433
30Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1Journal of Virology2002424
31The Akt kinases: Isoform specificity in metabolism and cancerCell Cycle2009424
32Glutathione is present in high concentrations in cultured astrocytes but not in cultured neuronsBrain Research1989411
33Vitamin E, Ascorbate, Glutathione, Glutathicne Disulfide, and Enzymes of Glutathione Metabolism in Cultures of Chick Astrocytes and Neurons: Evidence that Astrocytes Play an Important Role in Antioxidative Processes in the BrainJournal of Neurochemistry1994388
34Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous systemNature Cell Biology2000386
35MEMBRANE DOMAINSAnnual Review of Cell and Developmental Biology2004381
36Metabolic Enzymes of Mycobacteria Linked to Antioxidant Defense by a Thioredoxin-Like ProteinScience2002378
37Glutathione, a first line of defense against cadmium toxicityFASEB Journal1987372
38[1] Glutathione metabolismMethods in Enzymology1995372
39Dynamic Coupling between the SH2 and SH3 Domains of c-Src and Hck Underlies Their Inactivation by C-Terminal Tyrosine PhosphorylationCell2001366
40Theoretical and computational models of biological ion channelsQuarterly Reviews of Biophysics2004362
41Endocytic Sorting of Lipid Analogues Differing Solely in the Chemistry of Their Hydrophobic TailsJournal of Cell Biology1999359
42Ion Permeation and Selectivity of OmpF Porin: A Theoretical Study Based on Molecular Dynamics, Brownian Dynamics, and Continuum Electrodiffusion TheoryJournal of Molecular Biology2002353
43Acquisition of siderophores in Gram-negative bacteriaNature Reviews Molecular Cell Biology2003349
44Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens.Proceedings of the National Academy of Sciences of the United States of America1990348
45p21 as a Common Signaling Target of Reactive Free Radicals and Cellular Redox StressJournal of Biological Chemistry1995347
46Glutathione monoethyl ester: Preparation, uptake by tissues, and conversion to glutathioneArchives of Biochemistry and Biophysics1985344
47On the antioxidant effects of ascorbic acid and glutathioneBiochemical Pharmacology1992342
48Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle traffickingNature2004341
49Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase ActivationJournal of Biological Chemistry2007321
50Ribonucleotide reductase and cancer: biological mechanisms and targeted therapiesOncogene2015321