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Top Articles

#TitleJournalYearCitations
1A comparative encyclopedia of DNA elements in the mouse genomeNature20141,444
2The perivascular niche regulates breast tumour dormancyNature Cell Biology2013945
3Molecular mechanisms of fibrinolysisBritish Journal of Haematology2005570
4Organization of vesicular trafficking in epitheliaNature Reviews Molecular Cell Biology2005570
5Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial CellsCell Stem Cell2009548
6Whole‐genome sequencing identifies EN1 as a determinant of bone density and fractureNature2015483
7Sonic hedgehog Signaling Regulates Gli2 Transcriptional Activity by Suppressing Its Processing and DegradationMolecular and Cellular Biology2006459
8Restoration of vision after transplantation of photoreceptorsNature2012447
9Hypertension and Cerebrovascular DysfunctionCell Metabolism2008425
10Growth and folding of the mammalian cerebral cortex: from molecules to malformationsNature Reviews Neuroscience2014419
11Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophilsNature Immunology2009362
12Annexin II regulates fibrin homeostasis and neoangiogenesis in vivoJournal of Clinical Investigation2004323
13An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/ wingless signaling pathwayProceedings of the National Academy of Sciences of the United States of America2011300
14Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural CrestCell2015299
15Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking αvβ5 IntegrinJournal of Experimental Medicine2004295
16Wnt Signaling and Breast CancerCancer Biology and Therapy2004288
17Homeostatic Mechanisms in Articular Cartilage and Role of Inflammation in OsteoarthritisCurrent Rheumatology Reports2013259
18Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolutionScience2014244
19Fibronectins in vascular morphogenesisAngiogenesis2009222
20Different timings of dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous systemDevelopmental Dynamics2009218
21Wnt Proteins in Mammary Development and CancerJournal of Mammary Gland Biology and Neoplasia2004210
22An Annexin 2 Phosphorylation Switch Mediates p11-dependent Translocation of Annexin 2 to the Cell SurfaceJournal of Biological Chemistry2004206
23Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiationCancer Research2003206
24Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarctionNature Cell Biology2009205
25Wnt5a Signaling Induces Proliferation and Survival of Endothelial Cells In Vitro and Expression of MMP-1 and Tie-2Molecular Biology of the Cell2006196
26Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNAProceedings of the National Academy of Sciences of the United States of America2012185
27Clathrin is a key regulator of basolateral polarityNature2008182
28The cell biology of visionJournal of Cell Biology2010182
29Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancerCancer Research2002182
30Ribosomal Protein SA Haploinsufficiency in Humans with Isolated Congenital AspleniaScience2013176
31MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse NeocortexCell Reports2013170
32Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryoDevelopment (Cambridge)2008162
33Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndromeBlood2006159
34Wnt Proteins Induce Dishevelled Phosphorylation via an LRP5/6- Independent Mechanism, Irrespective of Their Ability To Stabilize β-CateninMolecular and Cellular Biology2004155
35A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial ApoptosisDevelopmental Cell2011154
36Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and functionNeuroscience2013150
37Wnt signalling regulates myogenic differentiation in the developing avian wingDevelopment (Cambridge)2003148
38HER2/neu-Induced Mammary Tumorigenesis and Angiogenesis Are Reduced in Cyclooxygenase-2 Knockout MiceCancer Research2005145
39The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cellsProceedings of the National Academy of Sciences of the United States of America2007145
40Functions of Noncoding RNAs in Neural Development and Neurological DiseasesMolecular Neurobiology2011144
41The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogasterPLoS Genetics2015143
42Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment EpitheliumJournal of Biological Chemistry2006142
43Migrating fibroblasts perform polarized, microtubule-dependent exocytosis towards the leading edgeJournal of Cell Science2003139
44EGFL7: a unique angiogenic signaling factor in vascular development and diseaseBlood2012139
45Suppression of miRNA-708 by Polycomb Group Promotes Metastases by Calcium-Induced Cell MigrationCancer Cell2013135
46A genomewide survey of developmentally relevant genes in Ciona intestinalisDevelopment Genes and Evolution2003130
47Intravital imaging of embryonic and tumor neovasculature using viral nanoparticlesNature Protocols2010129
48Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivoBlood2009123
49Neutrophil phenotypes and functions in cancer: A consensus statementJournal of Experimental Medicine2022119
50Ciona intestinalis: Chordate development made simpleDevelopmental Dynamics2005118