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Top Articles

#TitleJournalYearCitations
1The landscape of somatic copy-number alteration across human cancersNature20103,331
2Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
3Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancerNature Genetics20121,300
4DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicityNature Communications20171,194
5The genomic complexity of primary human prostate cancerNature20111,107
6Punctuated Evolution of Prostate Cancer GenomesCell20131,107
7Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphomaNature2009969
8Characterization of a rare IL-10–competent B-cell subset in humans that parallels mouse regulatory B10 cellsBlood2011969
9Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate CancerCell2009797
10Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDHScience2015722
11Kaposi's sarcoma and its associated herpesvirusNature Reviews Cancer2010692
12Banff ’09 Meeting Report: Antibody Mediated Graft Deterioration and Implementation of Banff Working GroupsAmerican Journal of Transplantation2010691
13XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathwayNature2014663
14Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencingNature Genetics2013662
15Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRILImmunity2007656
16ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell HomeostasisCell2015639
17B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleenNature Immunology2012615
18The regulation of IgA class switchingNature Reviews Immunology2008581
19Epigenetics and agingScience Advances2016568
20A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and OrganoidsCell Stem Cell2020543
21The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become CytolyticJournal of Immunology2004523
22The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancerNature Communications2014522
23Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophyNature Communications2015522
24Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein MProceedings of the National Academy of Sciences of the United States of America2011512
25Osteoblast-Osteoclast Communication and Bone HomeostasisCells2020485
26The Biology of Intestinal Immunoglobulin A ResponsesImmunity2008478
27Cancer/testis (CT) antigens: Potential targets for immunotherapyCancer Science2009478
28PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumorsNature Genetics2014472
29Novel YAP1‐TFE3 fusion defines a distinct subset of epithelioid hemangioendotheliomaGenes Chromosomes and Cancer2013463
30Somatic mutations precede acute myeloid leukemia years before diagnosisNature Medicine2018447
31Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanomaNature Medicine2010436
32An update on the biology of sphingosine 1-phosphate receptorsJournal of Lipid Research2014420
33The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussionBlood Cancer Journal2018404
34Carbapenemase-Producing Organisms: A Global ScourgeClinical Infectious Diseases2018397
35DCAFs, the Missing Link of the CUL4-DDB1 Ubiquitin LigaseMolecular Cell2007382
36Beyond PSA: The Next Generation of Prostate Cancer BiomarkersScience Translational Medicine2012378
37Kaposi sarcomaNature Reviews Disease Primers2019376
38Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophilsNature Immunology2009362
39The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma developmentNature Medicine2015359
40Identification of a Disease-Defining Gene Fusion in Epithelioid HemangioendotheliomaScience Translational Medicine2011328
41Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous DisseminationClinical Cancer Research2009318
42HIV-associated lymphomas and gamma-herpesvirusesBlood2009317
43Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic PathwayCell2014317
44Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSAScience Translational Medicine2011313
45B‐lymphocyte contributions to human autoimmune diseaseImmunological Reviews2008306
46Antibody-Based Detection of ERG Rearrangement-Positive Prostate CancerNeoplasia2010305
47Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesisNature2003289
48KSHV-Positive Solid Lymphomas Represent an Extra-Cavitary Variant of Primary Effusion LymphomaAmerican Journal of Surgical Pathology2004281
49Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cellsBlood2015281
50Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphomaBlood2012278