# | Title | Journal | Year | Citations |
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1 | The landscape of somatic copy-number alteration across human cancers | Nature | 2010 | 3,331 |
2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
3 | Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer | Nature Genetics | 2012 | 1,300 |
4 | DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity | Nature Communications | 2017 | 1,194 |
5 | The genomic complexity of primary human prostate cancer | Nature | 2011 | 1,107 |
6 | Punctuated Evolution of Prostate Cancer Genomes | Cell | 2013 | 1,107 |
7 | Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma | Nature | 2009 | 969 |
8 | Characterization of a rare IL-10–competent B-cell subset in humans that parallels mouse regulatory B10 cells | Blood | 2011 | 969 |
9 | Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer | Cell | 2009 | 797 |
10 | Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH | Science | 2015 | 722 |
11 | Kaposi's sarcoma and its associated herpesvirus | Nature Reviews Cancer | 2010 | 692 |
12 | Banff ’09 Meeting Report: Antibody Mediated Graft Deterioration and Implementation of Banff Working Groups | American Journal of Transplantation | 2010 | 691 |
13 | XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway | Nature | 2014 | 663 |
14 | Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing | Nature Genetics | 2013 | 662 |
15 | Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL | Immunity | 2007 | 656 |
16 | ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis | Cell | 2015 | 639 |
17 | B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen | Nature Immunology | 2012 | 615 |
18 | The regulation of IgA class switching | Nature Reviews Immunology | 2008 | 581 |
19 | Epigenetics and aging | Science Advances | 2016 | 568 |
20 | A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids | Cell Stem Cell | 2020 | 543 |
21 | The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic | Journal of Immunology | 2004 | 523 |
22 | The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer | Nature Communications | 2014 | 522 |
23 | Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy | Nature Communications | 2015 | 522 |
24 | Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 512 |
25 | Osteoblast-Osteoclast Communication and Bone Homeostasis | Cells | 2020 | 485 |
26 | The Biology of Intestinal Immunoglobulin A Responses | Immunity | 2008 | 478 |
27 | Cancer/testis (CT) antigens: Potential targets for immunotherapy | Cancer Science | 2009 | 478 |
28 | PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors | Nature Genetics | 2014 | 472 |
29 | Novel YAP1‐TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma | Genes Chromosomes and Cancer | 2013 | 463 |
30 | Somatic mutations precede acute myeloid leukemia years before diagnosis | Nature Medicine | 2018 | 447 |
31 | Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma | Nature Medicine | 2010 | 436 |
32 | An update on the biology of sphingosine 1-phosphate receptors | Journal of Lipid Research | 2014 | 420 |
33 | The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussion | Blood Cancer Journal | 2018 | 404 |
34 | Carbapenemase-Producing Organisms: A Global Scourge | Clinical Infectious Diseases | 2018 | 397 |
35 | DCAFs, the Missing Link of the CUL4-DDB1 Ubiquitin Ligase | Molecular Cell | 2007 | 382 |
36 | Beyond PSA: The Next Generation of Prostate Cancer Biomarkers | Science Translational Medicine | 2012 | 378 |
37 | Kaposi sarcoma | Nature Reviews Disease Primers | 2019 | 376 |
38 | Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophils | Nature Immunology | 2009 | 362 |
39 | The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development | Nature Medicine | 2015 | 359 |
40 | Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma | Science Translational Medicine | 2011 | 328 |
41 | Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination | Clinical Cancer Research | 2009 | 318 |
42 | HIV-associated lymphomas and gamma-herpesviruses | Blood | 2009 | 317 |
43 | Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway | Cell | 2014 | 317 |
44 | Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA | Science Translational Medicine | 2011 | 313 |
45 | B‐lymphocyte contributions to human autoimmune disease | Immunological Reviews | 2008 | 306 |
46 | Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer | Neoplasia | 2010 | 305 |
47 | Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis | Nature | 2003 | 289 |
48 | KSHV-Positive Solid Lymphomas Represent an Extra-Cavitary Variant of Primary Effusion Lymphoma | American Journal of Surgical Pathology | 2004 | 281 |
49 | Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells | Blood | 2015 | 281 |
50 | Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma | Blood | 2012 | 278 |