# | Title | Journal | Year | Citations |
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1 | Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis | Lancet, The | 2018 | 452 |
2 | Inhibition of Bruton tyrosine kinase in patients with severe COVID-19 | Science Immunology | 2020 | 304 |
3 | Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1 | New England Journal of Medicine | 2019 | 203 |
4 | The Role of NLRP3 and IL-1β in the Pathogenesis of Inflammatory Bowel Disease | Frontiers in Immunology | 2018 | 162 |
5 | Host Control of Fungal Infections: Lessons from Basic Studies and Human Cohorts | Annual Review of Immunology | 2018 | 151 |
6 | Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: A mechanistic model and tool for regimen and dose optimization | PLoS Medicine | 2019 | 139 |
7 | SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery | Blood | 2018 | 128 |
8 | PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis | Science | 2020 | 110 |
9 | Lessons from primary immunodeficiencies: Autoimmune regulator and autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy | Immunological Reviews | 2019 | 108 |
10 | Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring | Science | 2021 | 108 |
11 | Breakthrough Invasive Mold Infections in the Hematology Patient: Current Concepts and Future Directions | Clinical Infectious Diseases | 2018 | 82 |
12 | Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development | Nature Communications | 2019 | 82 |
13 | Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier | Science | 2021 | 75 |
14 | Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection | Journal of Infectious Diseases | 2019 | 72 |
15 | The present state of the tuberculosis drug development pipeline | Current Opinion in Pharmacology | 2018 | 70 |
16 | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design | Cell | 2018 | 67 |
17 | A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands | MBio | 2019 | 66 |
18 | Oral epithelial IL-22/STAT3 signaling licenses IL-17–mediated immunity to oral mucosal candidiasis | Science Immunology | 2020 | 66 |
19 | Immunity to commensal skin fungi promotes psoriasiform skin inflammation | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 62 |
20 | MAIT cell-directed therapy of Mycobacterium tuberculosis infection | Mucosal Immunology | 2021 | 57 |
21 | Architecture of the human PI4KIIIα lipid kinase complex | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 54 |
22 | Microglia activation in Niemann–Pick disease, type C1 is amendable to therapeutic intervention | Human Molecular Genetics | 2018 | 54 |
23 | Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies | Cell Host and Microbe | 2021 | 52 |
24 | Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology | Nature Communications | 2019 | 51 |
25 | Invasive Candidiasis Species Distribution and Trends, United States, 2009–2017 | Journal of Infectious Diseases | 2021 | 51 |
26 | Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells | Blood | 2021 | 51 |
27 | Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation | Science Immunology | 2021 | 50 |
28 | 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization | ACS Infectious Diseases | 2018 | 49 |
29 | Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions | Cell Reports | 2020 | 47 |
30 | A novel STING1 variant causes a recessive form of STING-associated vasculopathy with onset in infancy (SAVI) | Journal of Allergy and Clinical Immunology | 2020 | 45 |
31 | Roles of Three Cryptococcus neoformans and Cryptococcus gattii Efflux Pump-Coding Genes in Response to Drug Treatment | Antimicrobial Agents and Chemotherapy | 2018 | 43 |
32 | Current and future treatments for tuberculosis | BMJ, The | 2020 | 43 |
33 | Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT | Journal of Clinical Immunology | 2019 | 41 |
34 | Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair | Gene Therapy | 2021 | 39 |
35 | Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice | Journal of Experimental Medicine | 2021 | 38 |
36 | Editorial: NK Cell Subsets in Health and Disease: New Developments | Frontiers in Immunology | 2017 | 35 |
37 | The microbiome and immunodeficiencies: Lessons from rare diseases | Journal of Autoimmunity | 2019 | 35 |
38 | Fungal Infections with Ibrutinib and Other Small-Molecule Kinase Inhibitors | Current Fungal Infection Reports | 2019 | 34 |
39 | Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis | Journal of Clinical Immunology | 2020 | 33 |
40 | Myeloid Conditioning with c-kit-Targeted CAR-T Cells Enables Donor Stem Cell Engraftment | Molecular Therapy | 2018 | 32 |
41 | Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches | Journal of Medicinal Chemistry | 2019 | 32 |
42 | RELA haploinsufficiency in CD4 lymphoproliferative disease with autoimmune cytopenias | Journal of Allergy and Clinical Immunology | 2018 | 31 |
43 | The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS | Annals of the Rheumatic Diseases | 2022 | 31 |
44 | Discovery and Structure–Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2′-Oxidase | Journal of Medicinal Chemistry | 2018 | 29 |
45 | Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response | Cancer Immunology Research | 2021 | 29 |
46 | Emerging Aspergillus Species Almost Exclusively Associated With Primary Immunodeficiencies | Open Forum Infectious Diseases | 2018 | 28 |
47 | Heterozygous activating mutation in RAC2 causes infantile-onset combined immunodeficiency with susceptibility to viral infections | Clinical Immunology | 2019 | 27 |
48 | Organ-specific mechanisms linking innate and adaptive antifungal immunity | Seminars in Cell and Developmental Biology | 2019 | 27 |
49 | Gene Editing Rescues In vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System | Journal of Clinical Immunology | 2021 | 27 |
50 | APECED‐Associated Hepatitis: Clinical, Biochemical, Histological and Treatment Data From a Large, Predominantly American Cohort | Hepatology | 2021 | 25 |