| # | Title | Journal | Year | Citations |
|---|
| 1 | Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society | European Heart Journal | 2013 | 2,132 |
| 2 | Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and Women | JAMA - Journal of the American Medical Association | 2007 | 1,696 |
| 3 | Lipoprotein(a) as a cardiovascular risk factor: current status | European Heart Journal | 2010 | 1,392 |
| 4 | Genetically Elevated Lipoprotein(a) and Increased Risk of Myocardial Infarction | JAMA - Journal of the American Medical Association | 2009 | 977 |
| 5 | Statin Use and Reduced Cancer-Related Mortality | New England Journal of Medicine | 2012 | 798 |
| 6 | Loss-of-Function Mutations inAPOC3and Risk of Ischemic Vascular Disease | New England Journal of Medicine | 2014 | 749 |
| 7 | Genetically Elevated C-Reactive Protein and Ischemic Vascular Disease | New England Journal of Medicine | 2008 | 714 |
| 8 | A common coding variant in CASP8 is associated with breast cancer risk | Nature Genetics | 2007 | 591 |
| 9 | Familial Hypercholesterolemia in the Danish General Population: Prevalence, Coronary Artery Disease, and Cholesterol-Lowering Medication | Journal of Clinical Endocrinology and Metabolism | 2012 | 523 |
| 10 | Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array | Nature Genetics | 2013 | 492 |
| 11 | Fasting and Nonfasting Lipid Levels | Circulation | 2008 | 484 |
| 12 | C-reactive Protein As a Predictor of Prognosis in Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2007 | 456 |
| 13 | Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies | Lancet Neurology, The | 2012 | 445 |
| 14 | Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease | Science | 2016 | 438 |
| 15 | Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population | JAMA - Journal of the American Medical Association | 2008 | 429 |
| 16 | Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer | Critical Reviews in Clinical Laboratory Sciences | 2011 | 423 |
| 17 | Association of Loss-of-Function Mutations in the <emph type="ital">ABCA1</emph> Gene With High-Density Lipoprotein Cholesterol Levels and Risk of Ischemic Heart Disease | JAMA - Journal of the American Medical Association | 2008 | 422 |
| 18 | Extreme Lipoprotein(a) Levels and Risk of Myocardial Infarction in the General Population | Circulation | 2008 | 408 |
| 19 | A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer | Nature Genetics | 2014 | 408 |
| 20 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 21 | Baseline C-Reactive Protein Is Associated With Incident Cancer and Survival in Patients With Cancer | Journal of Clinical Oncology | 2009 | 359 |
| 22 | Inflammatory Biomarkers and Exacerbations in Chronic Obstructive Pulmonary Disease | JAMA - Journal of the American Medical Association | 2013 | 326 |
| 23 | Lipoprotein Lipase Mutations, Plasma Lipids and Lipoproteins, and Risk of Ischemic Heart Disease | Circulation | 1999 | 310 |
| 24 | Elevated HDL Cholesterol Is a Risk Factor for Ischemic Heart Disease in White Women When Caused by a Common Mutation in the Cholesteryl Ester Transfer Protein Gene | Circulation | 2000 | 288 |
| 25 | ACE Gene Polymorphism in Cardiovascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology | 2000 | 274 |
| 26 | C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization | International Journal of Obesity | 2011 | 267 |
| 27 | Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study | Nature Genetics | 2011 | 265 |
| 28 | CHEK2*1100delC Genotyping for Clinical Assessment of Breast Cancer Risk: Meta-Analyses of 26,000 Patient Cases and 27,000 Controls | Journal of Clinical Oncology | 2008 | 262 |
| 29 | Peripheral Blood Leukocyte Telomere Length and Mortality Among 64 637 Individuals From the General Population | Journal of the National Cancer Institute | 2015 | 258 |
| 30 | The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach | PLoS Medicine | 2012 | 246 |
| 31 | Low 25-Hydroxyvitamin D and Risk of Type 2 Diabetes: A Prospective Cohort Study and Metaanalysis | Clinical Chemistry | 2013 | 236 |
| 32 | Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts | BMJ, The | 2013 | 228 |
| 33 | HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial | Lancet, The | 2010 | 221 |
| 34 | Angiotensinogen Gene Polymorphism, Plasma Angiotensinogen, and Risk of Hypertension and Ischemic Heart Disease | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 212 |
| 35 | Extreme Lipoprotein(a) Levels and Improved Cardiovascular Risk Prediction | Journal of the American College of Cardiology | 2013 | 210 |
| 36 | 25-Hydroxyvitamin D Levels and Risk of Ischemic Heart Disease, Myocardial Infarction, and Early Death | Arteriosclerosis, Thrombosis, and Vascular Biology | 2012 | 209 |
| 37 | Base excess or buffer base (strong ion difference) as measure of a non‐respiratory acid‐base disturbance | Acta Anaesthesiologica Scandinavica | 1995 | 207 |
| 38 | Inflammatory Biomarkers and Comorbidities in Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2012 | 198 |
| 39 | Short Telomere Length, Cancer Survival, and Cancer Risk in 47102 Individuals | Journal of the National Cancer Institute | 2013 | 195 |
| 40 | Factor V Leiden: The Copenhagen City Heart Study and 2 meta-analyses | Blood | 2002 | 188 |
| 41 | 25‐Hydroxyvitamin D and symptomatic ischemic stroke: An Original Study and Meta‐Analysis | Annals of Neurology | 2013 | 186 |
| 42 | Hemochromatosis mutations in the general population: iron overload progression rate | Blood | 2004 | 177 |
| 43 | PALB2,CHEK2andATMrare variants and cancer risk: data from COGS | Journal of Medical Genetics | 2016 | 174 |
| 44 | Short Telomere Length, Myocardial Infarction, Ischemic Heart Disease, and Early Death | Arteriosclerosis, Thrombosis, and Vascular Biology | 2012 | 172 |
| 45 | Remnant cholesterol as a cause of ischemic heart disease: Evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment | | 2014 | 167 |
| 46 | Association of Mutations in the Apolipoprotein B Gene with Hypercholesterolemia and the Risk of Ischemic Heart Disease | New England Journal of Medicine | 1998 | 166 |
| 47 | Lipoprotein(a) and Risk of Type 2 Diabetes | Clinical Chemistry | 2010 | 165 |
| 48 | Myocardial Infarction and Ischemic Heart Disease in Overweight and Obesity With and Without Metabolic Syndrome | JAMA Internal Medicine | 2014 | 165 |
| 49 | Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: the Copenhagen City Heart Study with 31 years of follow-up | Journal of Internal Medicine | 2011 | 163 |
| 50 | A common mutation (G-455--> A) in the beta-fibrinogen promoter is an independent predictor of plasma fibrinogen, but not of ischemic heart disease. A study of 9,127 individuals based on the Copenhagen City Heart Study. | Journal of Clinical Investigation | 1997 | 159 |
