| # | Title | Journal | Year | Citations |
|---|
| 1 | Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial | Lancet, The | 2005 | 1,105 |
| 2 | Colorectal cancer screening: a global overview of existing programmes | Gut | 2015 | 899 |
| 3 | A functional CFTR assay using primary cystic fibrosis intestinal organoids | Nature Medicine | 2013 | 800 |
| 4 | Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED) | Endoscopy | 2012 | 594 |
| 5 | 3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 2: Surgical Management and Special Situations | Journal of Crohn's and Colitis | 2017 | 558 |
| 6 | Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis | Hepatology | 2013 | 519 |
| 7 | Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial | Lancet, The | 2018 | 504 |
| 8 | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma | Nature Genetics | 2011 | 501 |
| 9 | United European Gastroenterology evidence‐based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU) | United European Gastroenterology Journal | 2017 | 482 |
| 10 | Restriction of intestinal stem cell expansion and the regenerative response by YAP | Nature | 2013 | 463 |
| 11 | High Prevalence of Pancreatic Cysts Detected by Screening Magnetic Resonance Imaging Examinations | Clinical Gastroenterology and Hepatology | 2010 | 455 |
| 12 | The staging of gastritis with the OLGA system by using intestinal metaplasia as an accurate alternative for atrophic gastritis | Gastrointestinal Endoscopy | 2010 | 447 |
| 13 | Acute pancreatitis | Lancet, The | 2020 | 447 |
| 14 | Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis | Science Translational Medicine | 2016 | 428 |
| 15 | High Cancer Risk in Peutz–Jeghers Syndrome: A Systematic Review and Surveillance Recommendations | American Journal of Gastroenterology | 2010 | 426 |
| 16 | Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy | Gut | 2010 | 411 |
| 17 | Improved Prognosis of Patients With Primary Biliary Cirrhosis That Have a Biochemical Response to Ursodeoxycholic Acid | Gastroenterology | 2009 | 387 |
| 18 | The Toronto Consensus Statements for the Management of Inflammatory Bowel Disease in Pregnancy | Gastroenterology | 2016 | 373 |
| 19 | The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease | Journal of Crohn's and Colitis | 2015 | 369 |
| 20 | Outcome of surgical treatment for early adenocarcinoma of the esophagus or gastro-esophageal junction | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2005 | 328 |
| 21 | Long-term follow-up of alpha-interferon treatment of patients with chronic hepatitis B | Hepatology | 2004 | 321 |
| 22 | Endoscopic management of acute necrotizing pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) evidence-based multidisciplinary guidelines | Endoscopy | 2018 | 321 |
| 23 | The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases | Blood | 2008 | 319 |
| 24 | Myeloproliferative neoplasms in Budd-Chiari syndrome and portal vein thrombosis: a meta-analysis | Blood | 2012 | 303 |
| 25 | Guidelines for cell viability assays | Food Frontiers | 2020 | 289 |
| 26 | Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline | Endoscopy | 2012 | 282 |
| 27 | Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial | Lancet, The | 2015 | 276 |
| 28 | Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1 | Gastroenterology | 2014 | 268 |
| 29 | Systematic Review and Meta-Analysis of the Impact of Computed Tomography–Assessed Skeletal Muscle Mass on Outcome in Patients Awaiting or Undergoing Liver Transplantation | American Journal of Transplantation | 2016 | 264 |
| 30 | Long-term Outcomes of Endoscopic vs Surgical Drainage of the Pancreatic Duct in Patients With Chronic Pancreatitis | Gastroenterology | 2011 | 263 |
| 31 | Allogeneic Bone Marrow–Derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients With Crohn’s Disease | Gastroenterology | 2015 | 261 |
| 32 | International multicenter experience with an over-the-scope clipping device for endoscopic management of GI defects (with video) | Gastrointestinal Endoscopy | 2014 | 255 |
| 33 | Treatment with Peg-Interferon alpha-2b for HBeAg-Positive Chronic Hepatitis B: HBsAg Loss Is Associated with HBV Genotype | American Journal of Gastroenterology | 2006 | 249 |
| 34 | Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels | British Journal of Cancer | 2009 | 245 |
| 35 | The Yield of First-Time Endoscopic Ultrasonography in Screening Individuals at a High Risk of Developing Pancreatic Cancer | American Journal of Gastroenterology | 2009 | 241 |
| 36 | Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Updated August 2018 | Endoscopy | 2019 | 241 |
| 37 | Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract | Annals of Surgery | 2016 | 223 |
| 38 | One to 2-Year Surveillance Intervals Reduce Risk of Colorectal Cancer in Families With Lynch Syndrome | Gastroenterology | 2010 | 219 |
| 39 | Aberrant p53 protein expression is associated with an increased risk of neoplastic progression in patients with Barrett's oesophagus | Gut | 2013 | 214 |
| 40 | Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis | Cell Reports | 2019 | 214 |
| 41 | Increased colorectal cancer risk during follow-up in patients with hyperplastic polyposis syndrome: a multicentre cohort study | Gut | 2010 | 210 |
| 42 | Efficacy of Endoscopic Closure of Acute Perforations of the Gastrointestinal Tract | Clinical Gastroenterology and Hepatology | 2012 | 208 |
| 43 | Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus | Immunology | 2009 | 189 |
| 44 | Modulation of the cellular immune system by intravenous immunoglobulin | Trends in Immunology | 2008 | 186 |
| 45 | Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018 | Gut | 2018 | 185 |
| 46 | Challenges in the management of acute peptic ulcer bleeding | Lancet, The | 2013 | 178 |
| 47 | Majority of patients with inflammatory bowel disease in clinical remission have mucosal inflammation | Inflammatory Bowel Diseases | 2012 | 175 |
| 48 | High frequency of early colorectal cancer in inflammatory bowel disease | Gut | 2008 | 173 |
| 49 | Immunochemical Fecal Occult Blood Testing Is Equally Sensitive for Proximal and Distal Advanced Neoplasia | American Journal of Gastroenterology | 2012 | 173 |
| 50 | High intra-uterine exposure to infliximab following maternal anti-TNF treatment during pregnancy | Alimentary Pharmacology and Therapeutics | 2011 | 168 |
