| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Ferroptosis: molecular mechanisms and health implications | Cell Research | 2021 | 1,406 |
| 4 | The molecular machinery of regulated cell death | Cell Research | 2019 | 1,373 |
| 5 | Broadening horizons: the role of ferroptosis in cancer | Nature Reviews Clinical Oncology | 2021 | 1,216 |
| 6 | Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis | JAMA - Journal of the American Medical Association | 2017 | 1,166 |
| 7 | The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013 | Lancet, The | 2016 | 1,080 |
| 8 | A genomic storm in critically injured humans | Journal of Experimental Medicine | 2011 | 1,040 |
| 9 | Oxidative stress inhibits distant metastasis by human melanoma cells | Nature | 2015 | 964 |
| 10 | Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets | Nature Communications | 2015 | 879 |
| 11 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 12 | Ferroptosis: machinery and regulation | Autophagy | 2021 | 765 |
| 13 | Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis | Gastroenterology | 2018 | 695 |
| 14 | Laparoscopic training on bench models: better and more cost effective than operating room experience?11No competing interests declared. | Journal of the American College of Surgeons | 2000 | 683 |
| 15 | Long-term Follow-up After Bariatric Surgery | JAMA - Journal of the American Medical Association | 2014 | 664 |
| 16 | American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update | Journal of the American College of Surgeons | 2017 | 664 |
| 17 | A STING-activating nanovaccine for cancer immunotherapy | Nature Nanotechnology | 2017 | 649 |
| 18 | Prevention of Venous Thromboembolism in General Surgical Patients | Annals of Surgery | 1988 | 626 |
| 19 | Laparoscopic Dismembered Pyeloplasty | Journal of Urology | 1993 | 612 |
| 20 | Consensus guidelines for the definition, detection and interpretation of immunogenic cell death | | 2020 | 610 |
| 21 | Ferroptosis is a type of autophagy-dependent cell death | Seminars in Cancer Biology | 2020 | 552 |
| 22 | Surgical Complications Associated With Sentinel Lymph Node Biopsy: Results From a Prospective International Cooperative Group Trial | Annals of Surgical Oncology | 2006 | 506 |
| 23 | Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer | Cell Death and Differentiation | 2016 | 506 |
| 24 | Inadequate analgesia in emergency medicine | Annals of Emergency Medicine | 2004 | 487 |
| 25 | Pancreatic cancer stroma: an update on therapeutic targeting strategies | Nature Reviews Gastroenterology and Hepatology | 2020 | 458 |
| 26 | Global cancer surgery: delivering safe, affordable, and timely cancer surgery | Lancet Oncology, The | 2015 | 442 |
| 27 | Iron Metabolism in Ferroptosis | Frontiers in Cell and Developmental Biology | 2020 | 408 |
| 28 | Autophagy-Dependent Ferroptosis: Machinery and Regulation | Cell Chemical Biology | 2020 | 399 |
| 29 | Clinical Evaluation of an Acellular Allograft Dermal Matrix in Full-Thickness Burns | Journal of Burn Care and Research | 1996 | 389 |
| 30 | The Forgotten Hysterectomy | Obstetrics and Gynecology | 2006 | 373 |
| 31 | Factors Affecting Recurrence following Incisional Herniorrhaphy | World Journal of Surgery | 2000 | 366 |
| 32 | Disconnect Between Incidence of Nonperforated and Perforated Appendicitis | Annals of Surgery | 2007 | 359 |
| 33 | The release and activity of HMGB1 in ferroptosis | Biochemical and Biophysical Research Communications | 2019 | 350 |
| 34 | Cuproptosis: a copper-triggered modality of mitochondrial cell death | Cell Research | 2022 | 346 |
| 35 | The hallmarks of COVID-19 disease | PLoS Pathogens | 2020 | 342 |
| 36 | Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein | Autophagy | 2020 | 319 |
| 37 | Free radicals and lipid peroxidation mediated injury in burn trauma: the role of antioxidant therapy | Toxicology | 2003 | 312 |
| 38 | Fibrin sealants in surgical practice: An overview | American Journal of Surgery | 2001 | 309 |
| 39 | Ferroptosis in infection, inflammation, and immunity | Journal of Experimental Medicine | 2021 | 298 |
| 40 | Emergency Medical Services Intervals and Survival in Trauma: Assessment of the “Golden Hour” in a North American Prospective Cohort | Annals of Emergency Medicine | 2010 | 297 |
| 41 | The Miami International Evidence-based Guidelines on Minimally Invasive Pancreas Resection | Annals of Surgery | 2020 | 294 |
| 42 | The Importance of Fracture Pattern in Guiding Therapeutic Decision-Making in Patients with Hemorrhagic Shock and Pelvic Ring Disruptions | Journal of Trauma | 2002 | 293 |
| 43 | 27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth | Cell Reports | 2013 | 289 |
| 44 | Clockophagy is a novel selective autophagy process favoring ferroptosis | Science Advances | 2019 | 286 |
| 45 | The New ACS/APDS Skills Curriculum: Moving the Learning Curve Out of the Operating Room | Journal of Gastrointestinal Surgery | 2008 | 283 |
| 46 | Cellular degradation systems in ferroptosis | Cell Death and Differentiation | 2021 | 283 |
| 47 | Colorectal cancer in the young | American Journal of Surgery | 2004 | 282 |
| 48 | Lipid storage and lipophagy regulates ferroptosis | Biochemical and Biophysical Research Communications | 2019 | 281 |
| 49 | Dexmedetomidine Infusion During Laparoscopic Bariatric Surgery: The Effect on Recovery Outcome Variables | Anesthesia and Analgesia | 2008 | 272 |
| 50 | Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer | International Journal of Cancer | 1998 | 270 |
