| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Clinically applicable deep learning for diagnosis and referral in retinal disease | Nature Medicine | 2018 | 1,648 |
| 2 | A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis | The Lancet Digital Health | 2019 | 1,053 |
| 3 | Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial | Lancet, The | 2014 | 706 |
| 4 | The Lancet Global Health Commission on Global Eye Health: vision beyond 2020 | The Lancet Global Health | 2021 | 667 |
| 5 | Mapping the visual field to the optic disc in normal tension glaucoma eyes11The authors have no proprietary interest in the development or marketing of any product or instrument mentioned in this article. | Ophthalmology | 2000 | 655 |
| 6 | Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis | New England Journal of Medicine | 2015 | 652 |
| 7 | Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study | Lancet Oncology, The | 2020 | 590 |
| 8 | Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT | Ophthalmology | 2018 | 544 |
| 9 | Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration | Nature Biotechnology | 2018 | 539 |
| 10 | Teprotumumab for Thyroid-Associated Ophthalmopathy | New England Journal of Medicine | 2017 | 528 |
| 11 | Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial | Lancet, The | 2015 | 514 |
| 12 | Adalimumab in Patients with Active Noninfectious Uveitis | New England Journal of Medicine | 2016 | 496 |
| 13 | Multi-country real-life experience of anti-vascular endothelial growth factor therapy for wet age-related macular degeneration | British Journal of Ophthalmology | 2015 | 493 |
| 14 | A comparison of the causes of blindness certifications in England and Wales in working age adults (16–64 years), 1999–2000 with 2009–2010 | BMJ Open | 2014 | 486 |
| 15 | Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy | Nature Genetics | 1993 | 484 |
| 16 | Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis | Annals of Neurology | 2005 | 484 |
| 17 | Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. | British Journal of Ophthalmology | 1995 | 473 |
| 18 | ISCEV standard for clinical visual evoked potentials: (2016 update) | Documenta Ophthalmologica | 2016 | 473 |
| 19 | A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy | Nature Genetics | 1999 | 462 |
| 20 | A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X–linked retinitis pigmentosa (RP3) | Nature Genetics | 1996 | 459 |
| 21 | Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis | Lancet Neurology, The | 2017 | 434 |
| 22 | LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling | Nature | 2013 | 424 |
| 23 | Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension | Nature Medicine | 2020 | 416 |
| 24 | Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia | Nature Genetics | 2013 | 408 |
| 25 | Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial | Lancet, The | 2016 | 405 |
| 26 | Mutational hot spot within a new RPGR exon in X-linked retinitis pigmentosa | Nature Genetics | 2000 | 399 |
| 27 | Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke | Nature Genetics | 2012 | 384 |
| 28 | Partial recovery of visual function in a blind patient after optogenetic therapy | Nature Medicine | 2021 | 381 |
| 29 | Contact lenses and other risk factors in microbial keratitis | Lancet, The | 1991 | 369 |
| 30 | Global variations and time trends in the prevalence of primary open angle glaucoma (POAG): a systematic review and meta-analysis | British Journal of Ophthalmology | 2016 | 368 |
| 31 | Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease | American Journal of Human Genetics | 2017 | 367 |
| 32 | Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial | Lancet, The | 2019 | 361 |
| 33 | Prevalence of Age-Related Macular Degeneration in Europe | Ophthalmology | 2017 | 356 |
| 34 | The Association between Time Spent Outdoors and Myopia in Children and Adolescents | Ophthalmology | 2012 | 354 |
| 35 | The APOSTEL recommendations for reporting quantitative optical coherence tomography studies | Neurology | 2016 | 345 |
| 36 | Increasing Prevalence of Myopia in Europe and the Impact of Education | Ophthalmology | 2015 | 342 |
| 37 | EN FACE IMAGING OF PACHYCHOROID SPECTRUM DISORDERS WITH SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY | Retina | 2016 | 338 |
| 38 | Prevalence and Clinical Characteristics of Glaucoma in Adult Chinese: A Population-Based Study in Liwan District, Guangzhou | | 2006 | 335 |
| 39 | Anterior segment optical coherence tomography | Progress in Retinal and Eye Research | 2018 | 332 |
| 40 | Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis | New England Journal of Medicine | 2017 | 330 |
| 41 | Glaucoma in Adults—Screening, Diagnosis, and Management | JAMA - Journal of the American Medical Association | 2021 | 329 |
| 42 | Treatment of Chronic Macular Edema With Acetazolamide | JAMA Ophthalmology | 1988 | 321 |
| 43 | The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss | British Journal of Ophthalmology | 2013 | 321 |
| 44 | Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium | European Journal of Epidemiology | 2015 | 320 |
| 45 | Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective | Progress in Retinal and Eye Research | 2021 | 317 |
| 46 | Myelin-oligodendrocyte glycoprotein antibody-associated disease | Lancet Neurology, The | 2021 | 305 |
| 47 | Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis | Clinical and Experimental Ophthalmology | 2001 | 304 |
| 48 | Secukinumab in the Treatment of Noninfectious Uveitis: Results of Three Randomized, Controlled Clinical Trials | Ophthalmology | 2013 | 299 |
| 49 | The Argus® II Retinal Prosthesis System | Progress in Retinal and Eye Research | 2016 | 298 |
| 50 | MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study | Lancet Neurology, The | 2007 | 295 |
