# | Title | Journal | Year | Citations |
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1 | Preoperative Chemoradiotherapy Versus Immediate Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Results of the Dutch Randomized Phase III PREOPANC Trial | Journal of Clinical Oncology | 2020 | 665 |
2 | Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study | Lancet Oncology, The | 2016 | 607 |
3 | Analysis of DNA methylation in cancer: location revisited | Nature Reviews Clinical Oncology | 2018 | 486 |
4 | LC3/GABARAP family proteins: autophagy‐(un)related functions | FASEB Journal | 2016 | 471 |
5 | Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial | Lancet Oncology, The | 2018 | 426 |
6 | Global cancer incidence in older adults, 2012 and 2035: A population‐based study | International Journal of Cancer | 2019 | 396 |
7 | Pan-cancer image-based detection of clinically actionable genetic alterations | Nature Cancer | 2020 | 343 |
8 | Predicting outcomes in radiation oncology—multifactorial decision support systems | Nature Reviews Clinical Oncology | 2013 | 329 |
9 | Neoadjuvant Chemoradiotherapy Versus Upfront Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Long-Term Results of the Dutch Randomized PREOPANC Trial | Journal of Clinical Oncology | 2022 | 274 |
10 | Clinical evaluation of atlas and deep learning based automatic contouring for lung cancer | Radiotherapy and Oncology | 2018 | 256 |
11 | The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies | Nature Genetics | 2019 | 250 |
12 | Characteristics of triple-negative breast cancer | Journal of Cancer Research and Clinical Oncology | 2011 | 225 |
13 | TRIDENT-2: National Implementation of Genome-wide Non-invasive Prenatal Testing as a First-Tier Screening Test in the Netherlands | American Journal of Human Genetics | 2019 | 222 |
14 | Familial Pityriasis Rubra Pilaris Is Caused by Mutations in CARD14 | American Journal of Human Genetics | 2012 | 220 |
15 | Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆ | Annals of Oncology | 2021 | 204 |
16 | International Guidelines on Radiation Therapy for Breast Cancer During the COVID-19 Pandemic | Clinical Oncology | 2020 | 198 |
17 | Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER | Nature Communications | 2014 | 195 |
18 | PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 193 |
19 | Outcome of Patients with Non–Small Cell Lung Cancer and Brain Metastases Treated with Checkpoint Inhibitors | Journal of Thoracic Oncology | 2019 | 178 |
20 | Targeting Hypoxia to Improve Non–Small Cell Lung Cancer Outcome | Journal of the National Cancer Institute | 2018 | 177 |
21 | Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2017 | 175 |
22 | Quality of Life in Rectal Cancer Patients After Chemoradiation: Watch-and-Wait Policy Versus Standard Resection – A Matched-Controlled Study | Diseases of the Colon and Rectum | 2017 | 173 |
23 | Further evidence that culture media affect perinatal outcome: findings after transfer of fresh and cryopreserved embryos | Human Reproduction | 2012 | 171 |
24 | Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome | Clinical Cancer Research | 2018 | 164 |
25 | Assisted reproduction treatment and epigenetic inheritance | Human Reproduction Update | 2012 | 161 |
26 | Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis | Clinical Genetics | 2011 | 154 |
27 | Detection of clinically relevant copy-number variants by exome sequencing in a large cohort of genetic disorders | Genetics in Medicine | 2017 | 143 |
28 | Renal cancer and pneumothorax risk in Birt–Hogg–Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families | British Journal of Cancer | 2011 | 142 |
29 | Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis | Annals of Oncology | 2014 | 142 |
30 | ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer | Radiotherapy and Oncology | 2018 | 141 |
31 | American Association of Physicists in Medicine Task Group 263: Standardizing Nomenclatures in Radiation Oncology | International Journal of Radiation Oncology Biology Physics | 2018 | 140 |
32 | Hypoxia Induced Impairment of NK Cell Cytotoxicity against Multiple Myeloma Can Be Overcome by IL-2 Activation of the NK Cells | PLoS ONE | 2013 | 128 |
33 | Avulsion of puborectalis muscle and other risk factors for cystocele recurrence: a 2-year follow-up study | International Urogynecology Journal | 2012 | 119 |
34 | Influence of embryo culture medium (G5 and HTF) on pregnancy and perinatal outcome after IVF: a multicenter RCT | Human Reproduction | 2016 | 118 |
35 | Value of ADC measurements for nodal staging after chemoradiation in locally advanced rectal cancer—a per lesion validation study | European Radiology | 2011 | 117 |
36 | European Society for Radiotherapy and Oncology Advisory Committee in Radiation Oncology Practice consensus recommendations on patient selection and dose and fractionation for external beam radiotherapy in early breast cancer | Lancet Oncology, The | 2022 | 117 |
37 | Perinatal mortality and morbidity up to 28 days after birth among 743 070 low-risk planned home and hospital births: a cohort study based on three merged national perinatal databases | BJOG: an International Journal of Obstetrics and Gynaecology | 2015 | 115 |
38 | Level of Activation of the Unfolded Protein Response Correlates With Paneth Cell Apoptosis in Human Small Intestine Exposed to Ischemia/Reperfusion | Gastroenterology | 2011 | 114 |
39 | Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma | Gastric Cancer | 2019 | 114 |
40 | Citrulline a More Suitable Substrate than Arginine to Restore NO Production and the Microcirculation during Endotoxemia | PLoS ONE | 2012 | 114 |
41 | Early Life Exposure to Famine and Colorectal Cancer Risk: A Role for Epigenetic Mechanisms | PLoS ONE | 2009 | 104 |
42 | Radiation-induced lung toxicity – cellular and molecular mechanisms of pathogenesis, management, and literature review | Radiation Oncology | 2020 | 103 |
43 | EGFR mutated non-small cell lung cancer patients: More prone to development of bone and brain metastases? | Lung Cancer | 2014 | 102 |
44 | New Insights into the Molecular Characteristics of Pulmonary Carcinoids and Large Cell Neuroendocrine Carcinomas, and the Impact on Their Clinical Management | Journal of Thoracic Oncology | 2018 | 102 |
45 | Radiogenomics: Radiobiology Enters the Era of Big Data and Team Science | International Journal of Radiation Oncology Biology Physics | 2014 | 99 |
46 | Clinical features of large cell neuroendocrine carcinoma: a population-based overview | European Respiratory Journal | 2016 | 94 |
47 | Clinical risk factors of colorectal cancer in patients with serrated polyposis syndrome: a multicentre cohort analysis | Gut | 2017 | 94 |
48 | A Novel Less-invasive Approach for Axillary Staging After Neoadjuvant Chemotherapy in Patients With Axillary Node-positive Breast Cancer by Combining Radioactive Iodine Seed Localization in the Axilla With the Sentinel Node Procedure (RISAS): A Dutch Prospective Multicenter Validation Study | Clinical Breast Cancer | 2017 | 91 |
49 | Lifestyle, Diet, and Colorectal Cancer Risk According to (Epi)genetic Instability: Current Evidence and Future Directions of Molecular Pathological Epidemiology | Current Colorectal Cancer Reports | 2017 | 91 |
50 | AQP5 enriches for stem cells and cancer origins in the distal stomach | Nature | 2020 | 89 |