| # | Title | Journal | Year | Citations |
|---|
| 1 | A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants | Nature Genetics | 2016 | 1,167 |
| 2 | Oxygen Distribution and Consumption within the Retina in Vascularised and Avascular Retinas and in Animal Models of Retinal Disease | Progress in Retinal and Eye Research | 2001 | 532 |
| 3 | Close encounters of different kinds: Dendritic cells and NK cells take centre stage | Nature Reviews Immunology | 2005 | 493 |
| 4 | Lipofuscin of the retinal pigment epithelium: A review | Eye | 1995 | 321 |
| 5 | Retinal degeneration and local oxygen metabolism | Experimental Eye Research | 2005 | 295 |
| 6 | A Randomized Clinical Trial of Intravitreal Bevacizumab versus Intravitreal Dexamethasone for Diabetic Macular Edema | Ophthalmology | 2014 | 270 |
| 7 | Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus | Nature Genetics | 2013 | 269 |
| 8 | A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment | Cancer Research | 2018 | 269 |
| 9 | Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity | Nature Immunology | 2005 | 241 |
| 10 | Functional and Structural Recovery of the Retina after Gene Therapy in the RPE65 Null Mutation Dog | | 2003 | 235 |
| 11 | Tolerating Subretinal Fluid in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab Using a Treat-and-Extend Regimen | Ophthalmology | 2019 | 222 |
| 12 | Axial Length Variation Impacts on Superficial Retinal Vessel Density and Foveal Avascular Zone Area Measurements Using Optical Coherence Tomography Angiography | | 2017 | 215 |
| 13 | Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma | Nature Genetics | 2014 | 212 |
| 14 | A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25 | Nature Genetics | 2010 | 204 |
| 15 | Correlation of Histologic and Clinical Images to Determine the Diagnostic Value of Fluorescein Angiography for Studying Retinal Capillary Detail | | 2010 | 202 |
| 16 | A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14 | Nature Genetics | 2010 | 200 |
| 17 | Innate immunity defines the capacity of antiviral T cells to limit persistent infection | Journal of Experimental Medicine | 2010 | 190 |
| 18 | Environmental effects of ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2017 | Photochemical and Photobiological Sciences | 2018 | 177 |
| 19 | The influence of cerebrospinal fluid pressure on the lamina cribrosa tissue pressure gradient | Investigative Ophthalmology and Visual Science | 1995 | 177 |
| 20 | Directional dominance on stature and cognition in diverse human populations | Nature | 2015 | 173 |
| 21 | Quantitative Optical Coherence Tomography Angiography of Radial Peripapillary Capillaries in Glaucoma, Glaucoma Suspect, and Normal Eyes | American Journal of Ophthalmology | 2016 | 165 |
| 22 | Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma | PLoS Genetics | 2012 | 164 |
| 23 | Quantitative Confocal Imaging of the Retinal Microvasculature in the Human Retina | | 2012 | 163 |
| 24 | Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci | PLoS Genetics | 2010 | 161 |
| 25 | Quantitative Morphometry of Perifoveal Capillary Networks in the Human Retina | | 2012 | 161 |
| 26 | Retinal ganglion cells: Energetics, compartmentation, axonal transport, cytoskeletons and vulnerability | Progress in Retinal and Eye Research | 2013 | 160 |
| 27 | Registration of stereo and temporal images of the retina | IEEE Transactions on Medical Imaging | 1999 | 158 |
| 28 | Ozone depletion, ultraviolet radiation, climate change and prospects for a sustainable future | Nature Sustainability | 2019 | 156 |
| 29 | Adenovirus and Adeno-Associated Virus Vectors | DNA and Cell Biology | 2002 | 154 |
| 30 | Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial | Lancet, The | 2015 | 154 |
| 31 | Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity | Gene Therapy | 2005 | 153 |
| 32 | The correlation between cerebrospinal fluid pressure and retrolaminar tissue pressure | Investigative Ophthalmology and Visual Science | 1998 | 149 |
| 33 | Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment | Science Translational Medicine | 2019 | 147 |
| 34 | Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate | Photochemical and Photobiological Sciences | 2019 | 138 |
| 35 | Model of Endothelin-1–Induced Chronic Optic Neuropathy in Rat | | 2004 | 137 |
| 36 | Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 137 |
| 37 | Corneal replacement using a synthetic hydrogel cornea, AlphaCor™: device, preliminary outcomes and complications | Eye | 2003 | 136 |
| 38 | Perforin and Granzymes Have Distinct Roles in Defensive Immunity and Immunopathology | Immunity | 2006 | 134 |
| 39 | Phase 2a Randomized Clinical Trial: Safety and Post Hoc Analysis of Subretinal rAAV.sFLT-1 for Wet Age-related Macular Degeneration | EBioMedicine | 2016 | 124 |
| 40 | Long-term Evaluation of AAV-Mediated sFlt-1 Gene Therapy for Ocular Neovascularization in Mice and Monkeys | Molecular Therapy | 2005 | 120 |
| 41 | New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. | Human Molecular Genetics | 2017 | 120 |
| 42 | Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy | Gene Therapy | 2002 | 119 |
| 43 | Eomesodermin promotes the development of type 1 regulatory T (T R 1) cells | Science Immunology | 2017 | 118 |
| 44 | Axonal Transport and Cytoskeletal Changes in the Laminar Regions after Elevated Intraocular Pressure | | 2007 | 115 |
| 45 | The critical role of the conjunctiva in glaucoma filtration surgery | Progress in Retinal and Eye Research | 2009 | 115 |
| 46 | Intraretinal Oxygen Distribution in the Monkey Retina and the Response to Systemic Hyperoxia | | 2005 | 112 |
| 47 | Intraretinal oxygen levels before and after photoreceptor loss in the RCS rat | Investigative Ophthalmology and Visual Science | 2000 | 107 |
| 48 | Correlation between the radial peripapillary capillaries and the retinal nerve fibre layer in the normal human retina | Experimental Eye Research | 2014 | 103 |
| 49 | Characterization of a Mouse Model of Hyperglycemia and Retinal Neovascularization | American Journal of Pathology | 2010 | 102 |
| 50 | Inhibition of Angiogenesis by Adenovirus-Mediated sFlt-1 Expression in a Rat Model of Corneal Neovascularization | Human Gene Therapy | 2001 | 97 |
