| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica | Science | 2008 | 2,337 |
| 2 | Recent Developments in Myofibroblast Biology | American Journal of Pathology | 2012 | 1,068 |
| 3 | Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial | Lancet, The | 2019 | 885 |
| 4 | NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury | Nature Medicine | 2009 | 753 |
| 5 | Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome | Critical Care Medicine | 2016 | 695 |
| 6 | Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19 | JAMA - Journal of the American Medical Association | 2021 | 662 |
| 7 | Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance | Science Translational Medicine | 2014 | 580 |
| 8 | Clinical Risk Factors for Primary Graft Dysfunction after Lung Transplantation | American Journal of Respiratory and Critical Care Medicine | 2013 | 553 |
| 9 | Host Responses in Tissue Repair and Fibrosis | Annual Review of Pathology: Mechanisms of Disease | 2013 | 524 |
| 10 | Global Initiative for Chronic Obstructive Lung Disease | Journal of Cardiopulmonary Rehabilitation and Prevention | 2002 | 466 |
| 11 | Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial | Lancet Respiratory Medicine,the | 2017 | 452 |
| 12 | Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation | Blood | 2006 | 449 |
| 13 | Matrix Stiffness–Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction | American Journal of Respiratory Cell and Molecular Biology | 2012 | 431 |
| 14 | Tezacaftor–Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis | New England Journal of Medicine | 2017 | 427 |
| 15 | Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2015 | 412 |
| 16 | Pulmonary Arterial Enlargement and Acute Exacerbations of COPD | New England Journal of Medicine | 2012 | 411 |
| 17 | Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis | Journal of Clinical Investigation | 2013 | 368 |
| 18 | Systemic lupus erythematosus in three ethnic groups. XII. Risk factors for lupus nephritis after diagnosis | Lupus | 2002 | 324 |
| 19 | Developmental pathways in the pathogenesis of lung fibrosis | Molecular Aspects of Medicine | 2019 | 317 |
| 20 | The Relationship of Blood Product Ratio to Mortality: Survival Benefit or Survival Bias? | Journal of Trauma | 2009 | 314 |
| 21 | Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung | Cell | 2019 | 311 |
| 22 | Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome | JAMA Neurology | 2021 | 310 |
| 23 | Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2016 | 304 |
| 24 | Systemic lupus erythematosus in three ethnic groups. VIII. Predictors of early mortality in the LUMINA cohort | Arthritis and Rheumatism | 2001 | 303 |
| 25 | Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial | Lancet Respiratory Medicine,the | 2014 | 303 |
| 26 | Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis | Immunity | 2016 | 299 |
| 27 | Asthma Is Associated with Weight Gain in Females but Not Males, Independent of Physical Activity | American Journal of Respiratory and Critical Care Medicine | 2001 | 293 |
| 28 | Plasma Aldosterone Is Related to Severity of Obstructive Sleep Apnea in Subjects With Resistant Hypertension | Chest | 2007 | 288 |
| 29 | Pyruvate Dehydrogenase Kinase 1 Participates in Macrophage Polarization via Regulating Glucose Metabolism | Journal of Immunology | 2015 | 263 |
| 30 | Spironolactone reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a preliminary report | Journal of Human Hypertension | 2010 | 255 |
| 31 | Nitric Oxide and Nitrotyrosine in the Lungs of Patients with Acute Respiratory Distress Syndrome | American Journal of Respiratory and Critical Care Medicine | 2001 | 251 |
| 32 | Vitamin A is excreted in the urine during acute infection | American Journal of Clinical Nutrition | 1994 | 250 |
| 33 | Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission | Lancet, The | 2022 | 246 |
| 34 | What's in a name? That which we call IPF, by any other name would act the same | European Respiratory Journal | 2018 | 242 |
| 35 | Participation of miR-200 in Pulmonary Fibrosis | American Journal of Pathology | 2012 | 235 |
| 36 | Pediatric acute renal failure: outcome by modality and disease | Pediatric Nephrology | 2001 | 231 |
| 37 | Sleep and Hypertension | Chest | 2010 | 228 |
| 38 | Formaldehyde Exposure and Asthma in Children: A Systematic Review | Environmental Health Perspectives | 2010 | 227 |
| 39 | Identification of a microRNA signature in renal fibrosis: role of miR-21 | American Journal of Physiology - Renal Physiology | 2011 | 227 |
| 40 | Airway Remodeling in Asthma | Frontiers in Medicine | 2020 | 227 |
| 41 | The Prevalence of Gastroesophageal Reflux in Asthma Patients without Reflux Symptoms | American Journal of Respiratory and Critical Care Medicine | 2000 | 218 |
| 42 | Extracellular matrix in lung development, homeostasis and disease | Matrix Biology | 2018 | 215 |
| 43 | GOLD 2011 disease severity classification in COPDGene: a prospective cohort study | Lancet Respiratory Medicine,the | 2013 | 211 |
| 44 | Effects of Esomeprazole 40 mg Twice Daily on Asthma | American Journal of Respiratory and Critical Care Medicine | 2006 | 210 |
| 45 | Altered DNA Methylation Profile in Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2012 | 210 |
| 46 | Computed Tomographic Measures of Pulmonary Vascular Morphology in Smokers and Their Clinical Implications | American Journal of Respiratory and Critical Care Medicine | 2013 | 200 |
| 47 | Outcomes of critically ill children requiring continuous renal replacement therapy | Journal of Critical Care | 2009 | 193 |
| 48 | Three-Dimensional Changes in Upper Airways of Patients With Obstructive Sleep Apnea Following Maxillomandibular Advancement | Journal of Oral and Maxillofacial Surgery | 2007 | 191 |
| 49 | MMP generated matrikines | Matrix Biology | 2015 | 191 |
| 50 | Identifying Risk for Massive Transfusion in the Relatively Normotensive Patient: Utility of the Prehospital Shock Index | Journal of Trauma | 2011 | 189 |
