# | Title | Journal | Year | Citations |
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1 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
2 | Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease | New England Journal of Medicine | 1996 | 3,358 |
3 | Time‐Dependent ROC Curves for Censored Survival Data and a Diagnostic Marker | Biometrics | 2000 | 2,211 |
4 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
5 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
6 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Nature Genetics | 2019 | 1,307 |
7 | Proteogenomic characterization of human colon and rectal cancer | Nature | 2014 | 1,219 |
8 | Risk Factors for Lung Cancer and for Intervention Effects in CARET, the Beta-Carotene and Retinol Efficacy Trial | Journal of the National Cancer Institute | 1996 | 1,143 |
9 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
10 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
11 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
12 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
13 | Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic, Prognostic, or Screening Marker | American Journal of Epidemiology | 2004 | 1,034 |
14 | Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers | Nature | 2008 | 934 |
15 | Body mass index and survival in women with breast cancer—systematic literature review and meta-analysis of 82 follow-up studies | Annals of Oncology | 2014 | 857 |
16 | Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients | Nature Medicine | 1997 | 837 |
17 | Night Shift Work, Light at Night, and Risk of Breast Cancer | Journal of the National Cancer Institute | 2001 | 790 |
18 | Quantifiable predictive features define epitope-specific T cell receptor repertoires | Nature | 2017 | 723 |
19 | Correlated Binary Regression with Covariates Specific to Each Binary Observation | Biometrics | 1988 | 712 |
20 | Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer | Cancer | 2004 | 699 |
21 | Low-Fat Dietary Pattern and Risk of Invasive Breast Cancer | JAMA - Journal of the American Medical Association | 2006 | 696 |
22 | Large-scale association analyses identify host factors influencing human gut microbiome composition | Nature Genetics | 2021 | 676 |
23 | Implementation of the women's health initiative study design | Annals of Epidemiology | 2003 | 655 |
24 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
25 | Impact of socioeconomic status on cancer incidence and stage at diagnosis: selected findings from the surveillance, epidemiology, and end results: National Longitudinal Mortality Study | Cancer Causes and Control | 2009 | 649 |
26 | Sexual Practices, Sexually Transmitted Diseases, and the Incidence of Anal Cancer | New England Journal of Medicine | 1987 | 624 |
27 | Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery | PLoS ONE | 2009 | 622 |
28 | Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages | Cell Metabolism | 2014 | 605 |
29 | Pivotal Evaluation of the Accuracy of a Biomarker Used for Classification or Prediction: Standards for Study Design | Journal of the National Cancer Institute | 2008 | 597 |
30 | Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer | Nature Genetics | 2009 | 597 |
31 | Smoking and Mortality — Beyond Established Causes | New England Journal of Medicine | 2015 | 587 |
32 | Differences in Breast Cancer Stage, Treatment, and Survival by Race and Ethnicity | Archives of Internal Medicine | 2003 | 576 |
33 | Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer | Nature Medicine | 2016 | 572 |
34 | Estimation of individual admixture: Analytical and study design considerations | Genetic Epidemiology | 2005 | 571 |
35 | Modeling targeted layered containment of an influenza pandemic in the United States | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 570 |
36 | Mendelian randomization of blood lipids for coronary heart disease | European Heart Journal | 2015 | 567 |
37 | HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials | Lancet, The | 2015 | 562 |
38 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
39 | Anal cancer incidence and survival: The Surveillance, Epidemiology, and End Results experience, 1973–2000 | Cancer | 2004 | 541 |
40 | A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33 | Nature Genetics | 2010 | 539 |
41 | Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data | BMJ, The | 2014 | 528 |
42 | Oral Cancer Risk in Relation to Sexual History and Evidence of Human Papillomavirus Infection | Journal of the National Cancer Institute | 1998 | 527 |
43 | Epigenetic clock analysis of diet, exercise, education, and lifestyle factors | Aging | 2017 | 521 |
44 | Detectable clonal mosaicism and its relationship to aging and cancer | Nature Genetics | 2012 | 519 |
45 | Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies | American Journal of Human Genetics | 2005 | 513 |
46 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
47 | The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target | Science | 2012 | 505 |
48 | Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array | Nature Genetics | 2013 | 492 |
49 | Recreational Physical Activity and the Risk of Breast Cancer in Postmenopausal Women | JAMA - Journal of the American Medical Association | 2003 | 487 |
50 | flowCore: a Bioconductor package for high throughput flow cytometry | BMC Bioinformatics | 2009 | 484 |