# | Title | Journal | Year | Citations |
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1 | LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells | Cell Metabolism | 2016 | 1,218 |
2 | Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium | Lancet Infectious Diseases, The | 2019 | 1,083 |
3 | Wnt/β-catenin signaling controls development of the blood–brain barrier | Journal of Cell Biology | 2008 | 706 |
4 | Ubiquitination and selective autophagy | Cell Death and Differentiation | 2013 | 607 |
5 | Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 583 |
6 | Infarct Remodeling After Intracoronary Progenitor Cell Treatment in Patients With Acute Myocardial Infarction (TOPCARE-AMI) | Circulation | 2003 | 541 |
7 | Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells | Nature | 2015 | 521 |
8 | Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells | Blood | 2006 | 508 |
9 | Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies | Blood | 2012 | 426 |
10 | The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19 | European Respiratory Journal | 2020 | 421 |
11 | Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3–Internal Tandem Duplication Mutation (SORMAIN) | Journal of Clinical Oncology | 2020 | 369 |
12 | An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia | Blood | 2008 | 368 |
13 | Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy | Cell | 2017 | 358 |
14 | Prognostic Value of Minimal Residual Disease Quantification Before Allogeneic Stem-Cell Transplantation in Relapsed Childhood Acute Lymphoblastic Leukemia: The ALL-REZ BFM Study Group | Journal of Clinical Oncology | 2009 | 345 |
15 | European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies | Journal of Crohn's and Colitis | 2015 | 342 |
16 | Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure | JAMA Cardiology | 2019 | 336 |
17 | Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p | Blood | 2012 | 332 |
18 | Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or allogeneic haemopoietic stem-cell transplantation | Lancet Oncology, The | 2014 | 332 |
19 | High Levels of Wilms' Tumor Gene (wt1) mRNA in Acute Myeloid Leukemias Are Associated With a Worse Long-Term Outcome | Blood | 1997 | 321 |
20 | A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis | Molecular Therapy | 2008 | 319 |
21 | Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL) | Blood | 2006 | 312 |
22 | Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 312 |
23 | Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18–20 September 2008 | Leukemia | 2010 | 307 |
24 | The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms: a report of the BFM Group Study NHL-BFM95 | Blood | 2004 | 306 |
25 | Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis | Cancer Research | 2014 | 299 |
26 | A multiprotein supercomplex controlling oncogenic signalling in lymphoma | Nature | 2018 | 295 |
27 | Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes | Molecular Cell | 2009 | 285 |
28 | Risk of recurrent venous thrombosis in children with combined prothrombotic risk factors | Blood | 2001 | 272 |
29 | Cerebral Venous Thrombosis in Children | Circulation | 2003 | 270 |
30 | Long-Term Outcome in Children With Relapsed Acute Lymphoblastic Leukemia After Time-Point and Site-of-Relapse Stratification and Intensified Short-Course Multidrug Chemotherapy: Results of Trial ALL-REZ BFM 90 | Journal of Clinical Oncology | 2010 | 269 |
31 | Next-generation sequencing and real-time quantitative PCR for minimal residual disease detection in B-cell disorders | Leukemia | 2014 | 265 |
32 | Hepatosplenic T cell lymphoma. A review on 45 cases since the first report describing the disease as a distinct lymphoma entity in 1990 | Leukemia | 2000 | 258 |
33 | Dasatinib and low-intensity chemotherapy in elderly patients with Philadelphia chromosome–positive ALL | Blood | 2016 | 258 |
34 | Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues | Molecular and Cellular Proteomics | 2012 | 249 |
35 | Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment | Blood | 2017 | 248 |
36 | Gene therapy with adeno-associated virus vector 5–human factor IX in adults with hemophilia B | Blood | 2018 | 242 |
37 | Cellular Immunotherapy of Malignancies Using the Clonal Natural Killer Cell Line NK-92 | Journal of Hematotherapy and Stem Cell Research | 2001 | 232 |
38 | Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment | OncoImmunology | 2015 | 232 |
39 | Molecular relapse in adult standard-risk ALL patients detected by prospective MRD monitoring during and after maintenance treatment: data from the GMALL 06/99 and 07/03 trials | Blood | 2007 | 227 |
40 | Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) | Blood | 2007 | 227 |
41 | Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia | Cancer Cell | 2016 | 224 |
42 | Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study | Blood | 2007 | 223 |
43 | Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial | Lancet Oncology, The | 2018 | 216 |
44 | Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase | Leukemia | 2011 | 215 |
45 | Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy | Clinical Research in Cardiology | 2011 | 213 |
46 | Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93 | Leukemia | 2004 | 206 |
47 | Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 205 |
48 | CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies | Journal of Cellular and Molecular Medicine | 2016 | 202 |
49 | Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia | Nature Medicine | 2017 | 197 |
50 | Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations | Blood | 2013 | 186 |