| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,676 |
| 2 | Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and ‘self-microemulsifying’ drug delivery systems | European Journal of Pharmaceutical Sciences | 2000 | 958 |
| 3 | Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution | Nature Genetics | 2010 | 853 |
| 4 | Structural insights into µ-opioid receptor activation | Nature | 2015 | 780 |
| 5 | Vascular Pericytes Express Osteogenic Potential In Vitro and In Vivo | Journal of Bone and Mineral Research | 1998 | 501 |
| 6 | Peripheral cannabinoid receptor, CB2, regulates bone mass | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 492 |
| 7 | The incidence of primary glomerulonephritis worldwide: a systematic review of the literature | Nephrology Dialysis Transplantation | 2011 | 482 |
| 8 | Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition | Endocrine Reviews | 2005 | 468 |
| 9 | Qualitative Research: Data Collection, Analysis, and Management | Canadian Journal of Hospital Pharmacy | 2015 | 458 |
| 10 | Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle | Immunology | 2004 | 446 |
| 11 | Combating Sale of Counterfeit and Falsified Medicines Online: A Losing Battle | Frontiers in Pharmacology | 2017 | 422 |
| 12 | Chemokines and T Lymphocytes | Immunity | 1998 | 403 |
| 13 | Long non-coding RNAs in the regulation of the immune response | Trends in Immunology | 2014 | 401 |
| 14 | Biofilms and antibiotic therapy: Is there a role for combating bacterial resistance by the use of novel drug delivery systems? | Advanced Drug Delivery Reviews | 2005 | 391 |
| 15 | Regulation of Embryonic Stem Cell Self-renewal by Phosphoinositide 3-Kinase-dependent Signaling | Journal of Biological Chemistry | 2004 | 373 |
| 16 | The cancer chemopreventive actions of phytochemicals derived from glucosinolates | European Journal of Nutrition | 2008 | 343 |
| 17 | Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis | Nature Genetics | 2010 | 335 |
| 18 | Endosomes: A legitimate platform for the signaling train | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 329 |
| 19 | Key issues in non-viral gene delivery1PII of original article: S0169-409X(98)00048-9. The article was originally published in Advanced Drug Delivery Reviews 34 (1998) 3–19.1 | Advanced Drug Delivery Reviews | 2001 | 328 |
| 20 | Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose | Nature | 1999 | 317 |
| 21 | Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound | Pharmaceutical Research | 1992 | 316 |
| 22 | Myositis‐specific autoantibodies: an important tool to support diagnosis of myositis | Journal of Internal Medicine | 2016 | 306 |
| 23 | Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes | Nature Communications | 2014 | 291 |
| 24 | Intestinal permeation enhancers for oral peptide delivery | Advanced Drug Delivery Reviews | 2016 | 275 |
| 25 | Chemistry of Inositol Lipid Mediated Cellular Signaling | Angewandte Chemie International Edition in English | 1995 | 274 |
| 26 | Autoantibodies in myositis | Nature Reviews Rheumatology | 2018 | 272 |
| 27 | Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform | Nature Nanotechnology | 2018 | 265 |
| 28 | Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing | Gastroenterology | 2005 | 264 |
| 29 | Presynaptic Nicotinic Modulation of Dopamine Release in the Three Ascending Pathways Studied by In Vivo Microdialysis: Comparison of Naive and Chronic Nicotine‐Treated Rats | Journal of Neurochemistry | 1997 | 255 |
| 30 | Recent Developments in Vascular Endothelial Cell Transient Receptor Potential Channels | Circulation Research | 2005 | 246 |
| 31 | Individual dopaminergic neurons show raised iron levels in Parkinson disease | Neurology | 2007 | 241 |
| 32 | Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids | Journal of Controlled Release | 1998 | 236 |
| 33 | Transdermal drug delivery: 30 + years of war and still fighting! | Journal of Controlled Release | 2014 | 234 |
| 34 | Do patients have worse outcomes in heart failure than in cancer? A primary care‐based cohort study with 10‐year follow‐up in Scotland | European Journal of Heart Failure | 2017 | 232 |
| 35 | In Vivo Methods for the Assessment of Topical Drug Bioavailability | Pharmaceutical Research | 2008 | 223 |
| 36 | Key issues in non-viral gene delivery | Advanced Drug Delivery Reviews | 1998 | 221 |
| 37 | Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential | Journal of Medicinal Chemistry | 1994 | 215 |
| 38 | Spatial separation of endothelial small‐ and intermediate‐conductance calcium‐activated potassium channels (KCa) and connexins: possible relationship to vasodilator function? | Journal of Anatomy | 2006 | 210 |
| 39 | The CXC Chemokine Stromal Cell-Derived Factor Activates a Gi-Coupled Phosphoinositide 3-Kinase in T Lymphocytes | Journal of Immunology | 1999 | 209 |
| 40 | Qualitative Research: Getting Started | Canadian Journal of Hospital Pharmacy | 2014 | 206 |
| 41 | Chemokines: understanding their role in T-lymphocyte biology | Biochemical Journal | 1998 | 204 |
| 42 | Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate | Structure | 1999 | 204 |
| 43 | Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients | Journal of Autoimmunity | 2019 | 203 |
| 44 | Modulation of Endothelial Cell K Ca 3.1 Channels During Endothelium-Derived Hyperpolarizing Factor Signaling in Mesenteric Resistance Arteries | Circulation Research | 2008 | 200 |
| 45 | Optically pure, water-stable metallo-helical ‘flexicate’ assemblies with antibiotic activity | Nature Chemistry | 2012 | 200 |
| 46 | Sperm chromatin damage associated with male smoking | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1999 | 196 |
| 47 | Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) | Blood | 2007 | 189 |
| 48 | Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test. | Proceedings of the National Academy of Sciences of the United States of America | 1989 | 186 |
| 49 | Insights into the activation mechanism of class I HDAC complexes by inositol phosphates | Nature Communications | 2016 | 185 |
| 50 | Refsum's disease: a peroxisomal disorder affecting phytanic acid alpha-oxidation | Journal of Neurochemistry | 2002 | 184 |
