| # | Title | Journal | Year | Citations |
|---|
| 1 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 2 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 3 | A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis | American Journal of Human Genetics | 2004 | 1,313 |
| 4 | Functional variants of OCTN cation transporter genes are associated with Crohn disease | Nature Genetics | 2004 | 749 |
| 5 | Robust variance-components approach for assessing genetic linkage in pedigrees | American Journal of Human Genetics | 1994 | 572 |
| 6 | Common 5p15.33 and 6p21.33 variants influence lung cancer risk | Nature Genetics | 2008 | 510 |
| 7 | STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement | PLoS Medicine | 2009 | 411 |
| 8 | Gastric cancer—molecular and clinical dimensions | Nature Reviews Clinical Oncology | 2013 | 376 |
| 9 | CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade | Cancer Discovery | 2018 | 323 |
| 10 | Shortened Telomere Length Is Associated with Increased Risk of Cancer: A Meta-Analysis | PLoS ONE | 2011 | 292 |
| 11 | Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer | Gastroenterology | 2019 | 270 |
| 12 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L | Molecular Psychiatry | 2014 | 241 |
| 13 | Gene and pathway-based second-wave analysis of genome-wide association studies | European Journal of Human Genetics | 2010 | 228 |
| 14 | Impact of Enhanced Detection on the Increase in Thyroid Cancer Incidence in the United States: Review of Incidence Trends by Socioeconomic Status Within the Surveillance, Epidemiology, and End Results Registry, 1980–2008 | Thyroid | 2013 | 221 |
| 15 | Genetic variants and risk of lung cancer in never smokers: a genome-wide association study | Lancet Oncology, The | 2010 | 218 |
| 16 | PTPN22 Genetic Variation: Evidence for Multiple Variants Associated with Rheumatoid Arthritis | American Journal of Human Genetics | 2005 | 215 |
| 17 | Phytoestrogen intake and prostate cancer: A case‐control study using a new database | Nutrition and Cancer | 1999 | 211 |
| 18 | STrengthening the REporting of Genetic Association Studies (STREGA)—an extension of the STROBE statement | Genetic Epidemiology | 2009 | 211 |
| 19 | Osteoradionecrosis and Radiation Dose to the Mandible in Patients With Oropharyngeal Cancer | International Journal of Radiation Oncology Biology Physics | 2013 | 209 |
| 20 | Descriptive epidemiology and risk factors for head and neck cancer | Seminars in Oncology | 2004 | 184 |
| 21 | Effects of Nativity, Age at Migration, and Acculturation on Smoking Among Adult Houston Residents of Mexican Descent | American Journal of Public Health | 2005 | 168 |
| 22 | Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement | Human Genetics | 2009 | 167 |
| 23 | Chromosome 7p11.2 (EGFR) variation influences glioma risk | Human Molecular Genetics | 2011 | 158 |
| 24 | Assessing genetic linkage and association with robust components of variance approaches | Annals of Human Genetics | 1996 | 155 |
| 25 | A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation | PLoS Genetics | 2012 | 141 |
| 26 | Associations among physical activity, body mass index, and health‐related quality of life by race/ethnicity in a diverse sample of breast cancer survivors | Cancer | 2012 | 141 |
| 27 | ERCC1 and ERCC2 Polymorphisms Predict Clinical Outcomes of Oxaliplatin-Based Chemotherapies in Gastric and Colorectal Cancer: A Systemic Review and Meta-analysis | Clinical Cancer Research | 2011 | 138 |
| 28 | Ignoring Linkage Disequilibrium among Tightly Linked Markers Induces False-Positive Evidence of Linkage for Affected Sib Pair Analysis | American Journal of Human Genetics | 2004 | 137 |
| 29 | Peutz-Jeghers syndrome: clinicopathology and molecular alterations | Cellular and Molecular Life Sciences | 2006 | 128 |
| 30 | Development of a database for assessing dietary phytoestrogen intake | Nutrition and Cancer | 1999 | 123 |
| 31 | Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations | Journal of Autoimmunity | 2010 | 123 |
| 32 | Genetic susceptibility to lung cancer: the role of DNA damage and repair | Cancer Epidemiology Biomarkers and Prevention | 2003 | 123 |
| 33 | Emergency Medical Service (EMS) systems in developed and developing countries | Injury | 2007 | 121 |
| 34 | Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant tools | Bioinformatics | 2012 | 121 |
| 35 | High-density SNP analysis of 642 Caucasian families with rheumatoid arthritis identifies two new linkage regions on 11p12 and 2q33 | Genes and Immunity | 2006 | 119 |
| 36 | FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2 | Pharmaceuticals | 2020 | 110 |
| 37 | Diabetes with early kidney involvement may shorten life expectancy by 16 years | Kidney International | 2017 | 109 |
| 38 | International comparison of prehospital trauma care systems | Injury | 2007 | 108 |
| 39 | Cumulative Risk Assessment: An Overview of Methodological Approaches for Evaluating Combined Health Effects from Exposure to Multiple Environmental Stressors | International Journal of Environmental Research and Public Health | 2012 | 105 |
| 40 | Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway | Gastroenterology | 2018 | 105 |
| 41 | Cardiac toxicity in association with chemotherapy and radiation therapy in a large cohort of older patients with non-small-cell lung cancer | Annals of Oncology | 2010 | 101 |
| 42 | Colorectal cancer in Egyptian patients under 40 years of age | International Journal of Cancer | 1997 | 100 |
| 43 | Genome-wide gene and pathway analysis | European Journal of Human Genetics | 2010 | 99 |
| 44 | Strengthening the reporting of genetic association studies (STREGA)—an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement | Journal of Clinical Epidemiology | 2009 | 98 |
| 45 | Just-in-Time Feedback in Diet and Physical Activity Interventions: Systematic Review and Practical Design Framework | Journal of Medical Internet Research | 2018 | 97 |
| 46 | Sulfotransferase (SULT) 1A1 polymorphism as a predisposition factor for lung cancer: a case-control analysis | Lung Cancer | 2002 | 94 |
| 47 | Lung cancer risk in germline p53 mutation carriers: association between an inherited cancer predisposition, cigarette smoking, and cancer risk | Human Genetics | 2003 | 94 |
| 48 | Molecular epidemiology, cancer-related symptoms, and cytokines pathway | Lancet Oncology, The | 2008 | 92 |
| 49 | Adding Further Power to the Haseman and Elston Method for Detecting Linkage in Larger Sibships: Weighting Sums and Differences | Human Heredity | 2003 | 91 |
| 50 | Genetic Variants in Inflammation-Related Genes Are Associated with Radiation-Induced Toxicity Following Treatment for Non-Small Cell Lung Cancer | PLoS ONE | 2010 | 91 |
