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Top Articles

#TitleJournalYearCitations
1Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrationsNature Biotechnology20101,557
2Isolated Metal Atom Geometries as a Strategy for Selective Heterogeneous HydrogenationsScience20121,222
3Detection of Perchlorate and the Soluble Chemistry of Martian Soil at the Phoenix Lander SiteScience2009913
4In vivo degradation of three-dimensional silk fibroin scaffoldsBiomaterials2008679
5Phenotypic Consequences of Promoter-Mediated Transcriptional NoiseMolecular Cell2006591
6Single-Atom Alloy CatalysisChemical Reviews2020553
7Selective hydrogenation of 1,3-butadiene on platinum–copper alloys at the single-atom limitNature Communications2015484
8Pt/Cu single-atom alloys as coke-resistant catalysts for efficient C–H activationNature Chemistry2018472
9Role of Disulfide Bonds in Acrp30/Adiponectin Structure and Signaling SpecificityJournal of Biological Chemistry2003423
10A chemical-detecting system based on a cross-reactive optical sensor arrayNature1996406
11A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide StaplingJournal of the American Chemical Society2013389
12Tackling CO Poisoning with Single-Atom Alloy CatalystsJournal of the American Chemical Society2016374
13Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineeringNature Nanotechnology2014349
14Kinetics and Mechanisms of Formation and Reactivity of Non-heme Iron Oxygen IntermediatesChemical Reviews2005344
15Randomly Ordered Addressable High-Density Optical Sensor ArraysAnalytical Chemistry1998318
16Evidence for Calcium Carbonate at the Mars Phoenix Landing SiteScience2009300
17Conjugated circuits and resonance energies of benzenoid hydrocarbonsChemical Physics Letters1976295
18Fluorinated amino acids in protein design and engineeringChemical Society Reviews2002293
19An atomic-scale view of single-site Pt catalysis for low-temperature CO oxidationNature Catalysis2018292
20Single-Atom Alloys as a Reductionist Approach to the Rational Design of Heterogeneous CatalystsAccounts of Chemical Research2019291
21Molecular Rotors and Motors: Recent Advances and Future ChallengesACS Nano2009277
22Screening unlabeled DNA targets with randomly ordered fiber-optic gene arraysNature Biotechnology2000273
23Single atom alloy surface analogs in Pd0.18Cu15 nanoparticles for selective hydrogenation reactionsPhysical Chemistry Chemical Physics2013273
24Preparation of Polymer Coated Gold Nanoparticles by Surface-Confined Living Radical Polymerization at Ambient TemperatureNano Letters2002259
25Experimental demonstration of a single-molecule electric motorNature Nanotechnology2011246
26Atmospheric origins of perchlorate on Mars and in the AtacamaJournal of Geophysical Research2010245
27MOLECULAR BIOLOGY:Bead-based Fiber-Optic ArraysScience2000244
28Methods for 2-Deoxyglycoside SynthesisChemical Reviews2018235
29Antimicrobial Activity and Protease Stability of Peptides Containing Fluorinated Amino AcidsJournal of the American Chemical Society2007234
30Nanosphere−Microsphere Assembly:  Methods for Core−Shell Materials PreparationChemistry of Materials2001232
31Production of Hollow Polymeric Microspheres by Surface-Confined Living Radical Polymerization on Silica TemplatesChemistry of Materials2000230
32High-Density Fiber-Optic DNA Random Microsphere ArrayAnalytical Chemistry2000224
33Hydrogen Dissociation and Spillover on Individual Isolated Palladium AtomsPhysical Review Letters2009216
34On-Site Analysis of Arsenic in Groundwater Using a Microfabricated Gold Ultramicroelectrode ArrayAnalytical Chemistry2000213
35Lonely Atoms with Special Gifts: Breaking Linear Scaling Relationships in Heterogeneous Catalysis with Single-Atom AlloysJournal of Physical Chemistry Letters2018206
36A Fiber-Optic Microarray Biosensor Using Aptamers as ReceptorsAnalytical Biochemistry2000204
37Aqueous Solution/Air Interfaces Probed with Sum Frequency Generation SpectroscopyJournal of Physical Chemistry B2002204
38Microfabricated Array of Iridium Microdisks as a Substrate for Direct Determination of Cu2+or Hg2+Using Square-Wave Anodic Stripping VoltammetryAnalytical Chemistry1999203
39High-Speed Fluorescence Detection of Explosives-like VaporsAnalytical Chemistry2000200
40Collagen interactions: Drug design and deliveryAdvanced Drug Delivery Reviews2016195
41A fiber-optic DNA biosensor microarray for the analysis of gene expressionNature Biotechnology1996194
42Very High Density Sensing ArraysChemical Reviews2008193
43Paradoxical Role of the Kinetic‐Energy Operator in the Formation of the Covalent BondJournal of Chemical Physics1971187
44Getting in Shape: Controlling Peptide Bioactivity and Bioavailability Using Conformational ConstraintsACS Chemical Biology2013187
45Optical Methods for Single Molecule Detection and AnalysisAnalytical Chemistry2013185
46First-principles design of a single-atom–alloy propane dehydrogenation catalystScience2021185
47Convergent, Self-Encoded Bead Sensor Arrays in the Design of an Artificial NoseAnalytical Chemistry1999179
48Digital Concentration Readout of Single Enzyme Molecules Using Femtoliter Arrays and Poisson StatisticsNano Letters2006177
49Transitory microbial habitat in the hyperarid Atacama DesertProceedings of the National Academy of Sciences of the United States of America2018172
50Programmed Self-Sorting of Coiled Coils with Leucine and Hexafluoroleucine CoresJournal of the American Chemical Society2001170