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Department of Pathology and Laboratory Medicine
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top-articles
Department of Pathology and Laboratory Medicine
298
(top 1%)
papers
5.2K
(top 1%)
citations
37
(top 1%)
h
-index
59
(top 1%)
g
-index
332
all documents
6.1K
doc citations
1.7K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists
Journal of Medical Genetics
2015
187
2
ANRIL: A Regulator of VEGF in Diabetic Retinopathy
2017
143
3
lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy
Diabetologia
2019
141
4
Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2
Journal of Virology
2020
139
5
Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes
American Journal of Human Genetics
2018
135
6
An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences
Molecular Cell
2016
128
7
MALAT1: An Epigenetic Regulator of Inflammation in Diabetic Retinopathy
Scientific Reports
2018
123
8
Individuals with obesity and type 2 diabetes have additional immune dysfunction compared with obese individuals who are metabolically healthy
BMJ Open Diabetes Research and Care
2017
120
9
miR-146a mediates inflammatory changes and fibrosis in the heart in diabetes
Journal of Molecular and Cellular Cardiology
2017
118
10
Clinical Validation of Copy Number Variant Detection from Targeted Next-Generation Sequencing Panels
Journal of Molecular Diagnostics
2017
104
11
miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy
Diabetes
2016
102
12
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells
Molecular Cell
2017
99
13
Identification of Residues Controlling Restriction versus Enhancing Activities of IFITM Proteins on Entry of Human Coronaviruses
Journal of Virology
2018
97
14
Impacts and shortcomings of genetic clustering methods for infectious disease outbreaks
Virus Evolution
2016
87
15
Introduction of molecular HPV testing as the primary technology in cervical cancer screening: Acting on evidence to change the current paradigm
Preventive Medicine
2017
87
16
BAFopathies’ DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin–Siris and Nicolaides–Baraitser syndromes
Nature Communications
2018
83
17
The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance
Epigenetics
2017
79
18
Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension
Respirology
2019
76
19
LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2
Journal of Virology
2020
73
20
Kaempferol attenuates hyperglycemia-induced cardiac injuries by inhibiting inflammatory responses and oxidative stress
Endocrine
2018
72
21
Clinical utility of next‐generation sequencing in the diagnosis of hereditary haemolytic anaemias
British Journal of Haematology
2016
71
22
Clinical consequences of upfront pathology review in the randomised PORTEC-3 trial for high-risk endometrial cancer
Annals of Oncology
2018
71
23
Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome
Clinical Epigenetics
2019
71
24
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1
Genome Biology
2019
66
25
Inhibition of epidermal growth factor receptor attenuates atherosclerosis via decreasing inflammation and oxidative stress
Scientific Reports
2017
65
26
Ectomesenchymal Chondromyxoid Tumor
American Journal of Surgical Pathology
2018
60
27
The Khorana score for prediction of venous thromboembolism in cancer patients: An individual patient data meta‐analysis
Journal of Thrombosis and Haemostasis
2020
60
28
Lentivirus-mediated gene therapy for Fabry disease
Nature Communications
2021
58
29
Polycomb Repressive Complex 2 Regulates MiR-200b in Retinal Endothelial Cells: Potential Relevance in Diabetic Retinopathy
PLoS ONE
2015
58
30
The defining DNA methylation signature of Floating-Harbor Syndrome
Scientific Reports
2016
55
31
Phylogenetic Tools for Generalized HIV-1 Epidemics: Findings from the PANGEA-HIV Methods Comparison
Molecular Biology and Evolution
2017
53
32
A genome-wide DNA methylation signature for SETD1B-related syndrome
Clinical Epigenetics
2019
48
33
Bat SARS-Like WIV1 coronavirus uses the ACE2 of multiple animal species as receptor and evades IFITM3 restriction
via
TMPRSS2 activation of membrane fusion
Emerging Microbes and Infections
2020
48
34
Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis
Journal of Molecular Diagnostics
2016
47
35
miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes
PLoS ONE
2017
44
36
The Long Non-Coding RNA
HOTAIR
Is a Critical Epigenetic Mediator of Angiogenesis in Diabetic Retinopathy
2021
44
37
ANRIL regulates production of extracellular matrix proteins and vasoactive factors in diabetic complications
American Journal of Physiology - Endocrinology and Metabolism
2018
43
38
42936 pathogens from Canadian hospitals: 10 years of results (2007–16) from the CANWARD surveillance study
Journal of Antimicrobial Chemotherapy
2019
43
39
Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases
Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin
2020
42
40
Novel diagnostic DNA methylation episignatures expand and refine the epigenetic landscapes of Mendelian disorders
Human Genetics and Genomics Advances
2022
42
41
Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases
Oncotarget
2019
41
42
Frameshift mutations at the C-terminus of HIST1H1E result in a specific DNA hypomethylation signature
Clinical Epigenetics
2020
40
43
Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes in Patients Lacking Known
BRCA
Mutations
Human Mutation
2016
39
44
Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders
Journal of Molecular Diagnostics
2017
39
45
Genetic Cluster Analysis for HIV Prevention
Current HIV/AIDS Reports
2018
39
46
Circular RNA in colorectal cancer
Journal of Cellular and Molecular Medicine
2021
39
47
p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial
Modern Pathology
2022
39
48
Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer
Cancer Letters
2018
38
49
Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues
Frontiers in Oncology
2018
38
50
Kaempferol reduces K63-linked polyubiquitination to inhibit nuclear factor-κB and inflammatory responses in acute lung injury in mice
Toxicology Letters
2019
38
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